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Journal / Neuroscience / Optogenetic Stimulation of the Auditory Nerve
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Neuroscience

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JoVE Journal Neuroscience
Optogenetic Stimulation of the Auditory Nerve
 

Optogenetic Stimulation of the Auditory Nerve

Article DOI: 10.3791/52069-v • 10:53 min • October 8th, 2014
October 8th, 2014 •
1,2,5, 1,3, 3, 1, 1, 3, 1,2,4
1InnerEarLab, Department of Otolaryngology, University Medical Center Goettingen, 2Bernstein Focus for Neurotechnology, University of Goettingen, 3Auditory Systems Physiology Group, Department of Otolaryngology, University Medical Center Goettingen, 4Center for Nanoscale Microscopy and Molecular Physiology of the Brain, University of Goettingen, 5Department of Chemical, Electronic, and Biomedical Engineering, University of Guanajuato

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Cochlear implants (CIs) enable hearing by direct electrical stimulation of the auditory nerve. However, poor frequency and intensity resolution limits the quality of hearing with CIs. Here we describe optogenetic stimulation of the auditory nerve in mice as an alternative strategy for auditory research and developing future CIs.

Tags

Optogenetic Stimulation Auditory Nerve Spiral Ganglion Neurons Cochlear Implants Frequency Resolution Intensity Resolution Infrared Illumination Channelrhodopsin 2 CatCh Micro-light Emitting Diodes Optogenetic Auditory Brainstem Response OABR
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