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Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
 

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Article DOI: 10.3791/52598-v • 06:39 min • April 13th, 2015
April 13th, 2015 •
*1,2, *1, 1, 1, 1, 1
1Cardiac Muscle Research Laboratory, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 2Division of Cardiovascular Medicine, Chi-Mei Medical Center, Tainan
* These authors contributed equally

Capitoli

Riepilogo
Automatic Translation

Coronary flow reserve (CFR) is useful for assessment of myocardial oxygen demand and evaluation of cardiovascular risk. This study establishes a step-by-step transthoracic Doppler echocardiographic (TTDE) method for longitudinal monitoring of the changes in CFR, as measured from coronary artery in mice, under the experimental pressure overload of aortic banding.

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Keywords: Transthoracic Doppler Echocardiography Coronary Artery Flow Coronary Flow Reserve Pressure Overload Model Mice Septal Coronary Artery Aortic Banding Coronary Flow Velocity Systolic To Diastolic Peak Velocity Ratio Non-invasive Assessment Histopathology
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