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Behavior

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JoVE Journal Behavior
A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits
 

A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits

Article DOI: 10.3791/52973-v • 08:10 min • November 24th, 2015
November 24th, 2015 •
1,2, 1,2,3
1College of Agriculture, Ibaraki University, 2Cooperation between Agriculture and Medical Science, Ibaraki University, 3United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology

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Here, methods for developing a mouse model of subchronic and mild social defeat stress are described and used to investigate the pathogenic features of depression including hyperphagia- and polydipsia-like symptoms following increased body weight.

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Mouse Model Subchronic And Mild Social Defeat Stress Stress-induced Behavioral Deficits Stress-induced Physiological Deficits Animal Models Of Depression Chronic Social Defeat Stress SCSDS Paradigm Physical Contact Duration Body Weight Gain Food Intake Water Intake Social Behaviors Atypical Depression Pathogenic Mechanisms Stress-induced Weight Gain Polydipsia-like Symptoms Hyperphagia-like Symptoms
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