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A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy
 

A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy

Article DOI: 10.3791/53088-v • 05:17 min • October 27th, 2015
October 27th, 2015 •
*1, *2, 3
1Department of Family and Community Medicine, Thomas Jefferson University, 2Sidney Kimmel Medical College, Thomas Jefferson University, 3Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University
* These authors contributed equally

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Capillaroscopy is a non-invasive, efficient, relatively inexpensive and easy-to-learn methodology for directly visualizing capillaries in the microcirculation. However, only one publication to date describes the reliability of a complex software program available for quantitating capillaroscopy data. Here, we present a simple, reliable protocol for quantitating capillaries using a standardized algorithm.

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Keywords: Capillaroscopy Microcirculation Nailfold Computerized Method Quantitation Capillary Density Reproducible Automated Image Processing Semi-automated Counting Standardized Algorithm
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