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Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke
 

Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke

Article DOI: 10.3791/53089-v • 09:45 min • March 22nd, 2016
March 22nd, 2016 •
1, 1, 1, 1, 1
1Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, Western University

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To investigate the co-morbid Alzheimer's disease (AD) and stroke condition in a novel model, three behavior tasks are described that assess both motor control and cognitive behaviors. These tasks include the beam-walk task, cylinder task and Morris water maze.

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Keywords: Motor Function Spatial Learning Reference Memory Alzheimer's Disease Stroke Comorbid Model Behavioral Assessment Motor Deficit Cognitive Decline Dementia Preventative Compounds Cylinder Apparatus Video Tracking Four-limb Contacts
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