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1Department of Mechanical Engineering,Virginia Polytechnic Institute and State University, 2School of Biomedical Engineering and Sciences,Virginia Polytechnic Institute and State University, 3Department of Biology,University of Maryland, 4College of Engineering,University of Georgia, 5Department of Engineering Sciences and Mechanics,Virginia Polytechnic Institute and State University
Capitoli
- 00:05Titolo
- 00:48Preparation of Liposomes
- 02:00Manufacture of the Oil Reservoir and Preparation of Electrodes
- 04:06Setting Up the Experiment
- 06:22Formation of the Lipid Bilayer
- 07:49Results: Bilayer Formation and Activation of MscL Channels in Response to Harmonic Mechanical Stimuli
- 08:59Conclusion
Bakterielle mechanosensitive Kanäle können als mechanoelektrische Wandler in biomolekularen Geräten verwendet werden. Tropfenschnittstelle Doppelschichten (DIBs), Zell-inspirierten Bausteine für solche Geräte, stellen neue Plattformen zu integrieren und zu stimulieren mechanosensitive Kanäle. Hier zeigen wir, einen neuen Mikropipette Verfahren zur Bildung DIB, die die Untersuchung mechanosensitiver Kanäle unter mechanischer Stimulation.
