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1Department of Mechanical Engineering,Virginia Polytechnic Institute and State University, 2School of Biomedical Engineering and Sciences,Virginia Polytechnic Institute and State University, 3Department of Biology,University of Maryland, 4College of Engineering,University of Georgia, 5Department of Engineering Sciences and Mechanics,Virginia Polytechnic Institute and State University
Capitoli
- 00:05Titolo
- 00:48Preparation of Liposomes
- 02:00Manufacture of the Oil Reservoir and Preparation of Electrodes
- 04:06Setting Up the Experiment
- 06:22Formation of the Lipid Bilayer
- 07:49Results: Bilayer Formation and Activation of MscL Channels in Response to Harmonic Mechanical Stimuli
- 08:59Conclusion
Canales mechanosensitive bacterianas se pueden utilizar como transductores mechanoelectrical en dispositivos biomoleculares. Bicapas Gotita de interfaz (DIB), bloques de construcción de células de inspiración a este tipo de dispositivos, representan nuevas plataformas para incorporar y estimular canales mechanosensitive. Aquí, demostramos un nuevo método basado en la micropipeta de formar DIB, lo que permite el estudio de los canales mechanosensitive bajo estimulación mecánica.
