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Journal / Medicine / Orthotopic Hind Limb Transplantation in the Mouse
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JoVE Journal Medicine
Orthotopic Hind Limb Transplantation in the Mouse
 

Orthotopic Hind Limb Transplantation in the Mouse

Article DOI: 10.3791/53483-v • 07:15 min • February 12th, 2016
February 12th, 2016 •
*1, *1, *2, 3, 4, 1, 1, 1, 1
1Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA) Laboratory, Johns Hopkins University School of Medicine, 2Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, 3Center for Vascularized Composite Allotransplantation, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital and School of Medicine, 4Department of General, Visceral and Transplant Surgery, Charite Berlin
* These authors contributed equally

Capitoli

Riepilogo
Automatic Translation

This novel model for orthotopic hind limb transplantation in the mouse, applying a non-suture cuff technique for super-microvascular anastomosis, provides a powerful tool for in vivo mechanistic immunological research related to vascularized composite allotransplantation (VCA).

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Keywords: Orthotopic Hind Limb Transplantation Murine Model Non-suture Cuff Technique Super-microvascular Anastomosis Vascularized Composite Allografts Donor Limb Harvest Femoral Artery Femoral Vein Femoral Nerve Polyimide Cuffs Recipient Hind Limb Removal
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