Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Diffuse Optical Spectroscopy for the Quantitative …
JoVE Journal
Medicine

This Contenuto is Open Access.

JoVE Journal Medicine
Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
 

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Article DOI: 10.3791/53573-v • 06:21 min • May 27th, 2016
May 27th, 2016 •
1,2, 3, 1, 2, 4, 3, 1,3
1Department of Radiation Oncology, University of Toronto, 2Department of Physics, Ryerson University, 3Department of Medical Biophysics, University of Toronto, 4Ontario Cancer Institute / Campbell Family Institute for Cancer Research

Capitoli

Riepilogo
Automatic Translation

We present a diffuse optical spectroscopic (DOS) approach that provides quantitative optical biomarkers of skin response to radiation. We describe DOS instrumentation design, optical parameters extraction algorithms and the animal handling procedures required to yield representative data from a pre-clinical mouse model of radiation induced erythema.

Tags

Keywords: Diffuse Optical Spectroscopy Acute Ionizing Radiation Skin Toxicity Mouse Model Biomarker Radiation Therapy Radiation Skin Toxicity Reflectance Anesthesia Mouse Irradiation
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter