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JoVE Journal
Immunology and Infection

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Zebrafish as a Model to Assess the Teratogenic Potential of Nitrite
 

Zebrafish as a Model to Assess the Teratogenic Potential of Nitrite

Article DOI: 10.3791/53615-v 07:29 min February 16th, 2016
February 16th, 2016

Capitoli

Riepilogo

Exposure to teratogens may cause birth defects. Zebrafish are useful for determining the teratogenic potential of chemicals. We demonstrate the utility of zebrafish by exposing embryos to various levels of nitrite and also at different times of exposure. We show that nitrite can be toxic and cause severe developmental defects.

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Keywords: Zebrafish Developmental Toxicology Teratogenic Effects Nitrite Embryonic Development External Development Wild-type Strains Mating Fertilization Ethanol Sodium Nitrite
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