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急性心肌梗死的猪模型主要成果评估

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Medicina

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JoVE Journal Medicina

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

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急性心肌梗死的猪模型主要成果评估

DOI:

10.3791/54021-v

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14:19 min

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October 14, 2016

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Guilielmus H.J.M. Ellenbroek, Gerardus P.J. van Hout², Leo Timmers², Pieter A. Doevendans⁴, Gerard Pasterkamp³, Imo E. Hoefer³

¹Department of Experimental Cardiology,University Medical Center Utrecht, ²Department of Cardiology,University Medical Center Utrecht, ³Department of Clinical Chemistry and Hematology,University Medical Center Utrecht, ⁴Interuniversity Cardiology Institutes of the Netherlands (ICIN)

Capitoli

00:05Titolo
00:57Three Dimensional Transesophageal Echocardiography (3D-TEE)
03:14Admittance-based Pressure-volume (P-V) Loop Acquisition
07:44Area At Risk (AAR) and Infarct Size (IS) Quantification
11:44Results: 3D TEE and PV Loop Analysis Two Weeks Post-infarction
13:18Conclusion

Summary

Traduzione automatica

可靠和准确的结果评价是临床前的疗法转化为临床治疗的关键。目前的论文描述了如何评估猪急性心肌梗死模型的心脏功能和损坏3临床相关的主要成果参数。

Tags

Keywords: Acute Myocardial Infarction Pig Model Primary Outcome Assessment Ischemia Reperfusion Injury Cardiac Remodeling 3D Transesophageal Echocardiography Pressure-volume Loop Measurements Infarct Size Area At Risk Staining

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