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对大脑中动脉闭塞再灌注损伤诱发中风小鼠的手术方法
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JoVE Journal Medicina
Surgical Approach for Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke in Mice
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对大脑中动脉闭塞再灌注损伤诱发中风小鼠的手术方法

DOI:
10.3791/54302-v

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10:30 min

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October 20, 2016

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1Department of Molecular & Cellular Physiology, Health Sciences Center Shreveport,Louisiana State University

Capitoli

  • 00:05Titolo
  • 00:52Occlusion of the MCA
  • 03:24Reperfusion
  • 04:29Post-operative Neurological Scores and Measurement of Brain Infarct Volume
  • 07:59Results: Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke
  • 09:32Conclusion

Summary

Traduzione automatica

Traduzione automatica

为了了解中风的病理生理学，它使用可靠的模型是很重要的。本文将描述在小鼠中的最常用的中风模型中的一个，称为大脑中动脉闭塞（MCAO）模型（也称为腔内灯丝或缝合模型）再灌注。

Tags

Middle Cerebral Artery OcclusionIschemic StrokeLonga MethodMouse ModelAnesthesiaBody TemperatureCarotid Artery DissectionMonofilament InsertionReperfusionInfarct VolumeLeukocyte-endothelial Cell Interactions

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