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NFKB Aktivite ve Meme Kanseri Kök Hücreler önler Sentezi ve bir Aspirin-fumarat ön-ilacının Karakterizasyonu
JoVE Journal
Ricerca sul cancro
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JoVE Journal Ricerca sul cancro
Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
DOI:

13:38 min

January 18, 2017

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Capitoli

  • 00:05Titolo
  • 01:13Synthesis of Aspirin-fumarate Prodrug, GTCpFE
  • 06:10Inhibiting the NFκB Activity with GTCpFE in Breast Cancer Cells
  • 07:22Inhibiting Breast Cancer Stem Cells with GTCpFE In Vitro
  • 10:11Results: GTCpFE Inhibits the NFκB Pathway, Mammosphere Formation, and the CD44+CD24 Immunophenotype in Breast Cancer Cells
  • 11:49Conclusion

Summary

Traduzione automatica

This procedure will demonstrate how we synthesized and characterized the anti-NFκB and anti-cancer stem cell activity of an aspirin-fumarate prodrug.

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