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Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
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Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump

Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump

DOI:
10.3791/55086-v

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06:08 min

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March 11, 2017

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, , , ,
1College of Pharmacy,Yonsei University, 2College of Medicine,Yonsei University, 3Yonsei Institute of Pharmaceutical Sciences, 4Polyscientech Co. Ltd

Capitoli

  • 00:05Titolo
  • 00:56Preparation of Tubes and Drug Injections
  • 01:41Kinetic Sorption Study Using an Infusion Pump
  • 02:45Analysis of Drug Using High-performance Liquid Chromatography
  • 03:32Results: Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes
  • 04:33Conclusion

Summary

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We report a method for drug sorption evaluation using a pump and model drugs (diazepam and tacrolimus). After drug analysis using high-performance liquid chromatography, drug concentrations and sorption levels in the tubes of administration sets are calculated.

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Drug SorptionPVCNon-PVCAdministration SetsInfusion PumpTubeDrug SolutionHPLCUV DetectionCalibration CurveSample Collection

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