Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / System for Efficacy and Cytotoxicity Screening of …
JoVE Journal
Immunology and Infection

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto. Accedi o inizia la tua prova gratuita.

JoVE Journal Immunology and Infection
System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
 

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Article DOI: 10.3791/55273-v • 09:57 min • April 5th, 2017
April 5th, 2017 •
1, 1
1Department of Medicine, University of British Columbia

Capitoli

Riepilogo
Automatic Translation

We have developed a modular high-throughput screening system for discovering novel compounds against Mycobacterium tuberculosis, targeting intracellular and in-broth growing bacteria as well as cytotoxicity against the mammalian host cell.

Tags

Keywords: Mycobacterium Tuberculosis Intracellular Infection Macrophages Luciferase Assay Cytotoxicity MIC Drug Development THP1 Cells Opsonization MOI Differentiation 96-well Plate Compound Screening
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter