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多发性硬化症的小鼠模型EAE视神经炎及脑部炎症的生物发光和近红外成像
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Medicina
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JoVE Journal Medicina
Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice
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多发性硬化症的小鼠模型EAE视神经炎及脑部炎症的生物发光和近红外成像

DOI:
10.3791/55321-v

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08:05 min

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March 01, 2017

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,
1Institute of Clinical Pharmacology,University Hospital Frankfurt

Capitoli

  • 00:05Titolo
  • 00:54Immunization
  • 01:50EAE Course and Time of Imaging
  • 02:35Bioluminescent and Near-infrared Imaging of Optic Neuritis and Brain Inflammation
  • 03:41Image Analyses
  • 06:17Results: Time Course of Bioluminescence of Optic Neuritis and Assessment of Treatment Efficacy
  • 07:10Conclusion

Summary

Traduzione automatica

Traduzione automatica

我们表明用于体内实时生物发光和近红外中在SJL / J小鼠多发性硬化的实验性自身免疫性脑脊髓炎（EAE）模型视神经炎和脑炎的成像技术。

Tags

Keywords: BioluminescenceNear-infrared ImagingOptic NeuritisBrain InflammationEAE ModelMultiple SclerosisMiceNeuroimmunologyTherapyPTXPLP/CFACFAClinical SymptomsIn Vivo ImagingIsoflurane Anesthesia

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