Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Behavior / Systematic Assessment of Well-Being in Mice for…
JoVE Journal
Behavior

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto. Accedi o inizia la tua prova gratuita.

JoVE Journal Behavior
Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia
 

Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia

Article DOI: 10.3791/57046-v • 06:50 min • March 20th, 2018
March 20th, 2018 •
1,2, 2,3, 2, 4, 2, 1
1Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, 2Institute of Pharmacology and Toxicology, Department of Veterinary Medicine, Freie Universität Berlin, 3German Federal Institute for Risk Assessment (BfR), 4Unit of Physiology, Pathophysiology and Experimental Endocrinology, Department of Biomedical Sciences, University of Veterinary Medicine

Capitoli

Riepilogo
Automatic Translation

We developed a protocol to assess well-being in mice during procedures using general anesthesia. A series of behavioral parameters indicating levels of well-being as well as glucocorticoid metabolites were analyzed. The protocol can serve as a general aid to estimate the degree of severity in a scientific, animal-centered manner.

Tags

Keywords: Mouse Welfare Well-being Assessment General Anesthesia EU Directive 2010/63 Mouse Grimace Scale Burrowing Behavior Home Cage Activity Food Intake Nest Building Fecal Corticosterone Metabolites
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter