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自由运动大鼠脑电图记录过程中兴奋氨基酸的微透析
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Neuroscienze
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JoVE Journal Neuroscienze
Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
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自由运动大鼠脑电图记录过程中兴奋氨基酸的微透析

DOI:
10.3791/58455-v

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08:47 min

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November 08, 2018

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, , , , , ,
1Department of Medical Sciences, Section of Pharmacology, Neuroscience Center,University of Ferrara and National Institute of Neuroscience

Capitoli

  • 00:04Titolo
  • 00:42Epileptic Behavior Monitoring
  • 01:52Microdialysis Preparation
  • 03:54Microdialysis: Collection of Samples
  • 06:46Results: Extracellular Concentrations of Glutamate are Higher in Chronic Epileptic Rats
  • 07:34Conclusion

Summary

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Traduzione automatica

在这里, 我们描述了一种方法, 在体内微透析分析天冬氨酸和谷氨酸释放在腹侧海马的癫痫和非癫痫大鼠, 结合脑电图记录。天冬氨酸和谷氨酸的细胞外浓度可能与疾病的不同阶段有关。

Tags

Keywords: MicrodialysisExcitatory Amino AcidsEEGFreely Moving RatsNeurotransmitter ReleaseNeurological DiseasesFaraday CageEEG AmplifierEEG SoftwareEEG SignalTethered EEG Recording SystemAmplification FactorRinger’s SolutionFEP TubingGuide CannulaPlexiglass Cylinder

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