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Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
 

Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury

Article DOI: 10.3791/58641-v • 09:58 min • November 9th, 2018
November 9th, 2018 •
1,2, 2, 2, 2, 3, 2, 2, 2, 1, 1,2, 1, 4, 1
1Division of Neurosurgery, Rehabilitation Center for Traumatic Apallics Chiba, National Agency for Automotive Safety and Victims' Aid, 2Division of PET imaging, Rehabilitation Center for Traumatic Apallics Chiba, National Agency for Automotive Safety and Victims' Aid, 3Tokyo Nuclear Services Co. Ltd., 4Department of Neurological Surgery, Graduate School of Medicine, Chiba University

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[18F]-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography is useful for studying glucose metabolism related to brain function. Here, we present a protocol for an [18F]FDG tracer set-up and semiquantitative assessment of the region-of-interest analysis for targeted brain areas associated with clinical manifestations in patients with severe traumatic brain injury.

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Keywords: [18F]FDG Tracer Semi-quantitative Assessment Severe Brain Injury Unresponsive Wakefulness Syndrome Minimal Conscious State Cerebral Traumatic Brain Injury Automated FDG Synthesis Oxygen-16 Oxygen-18 Cyclotron Irradiation Mannose Triflate Acetonitrile Fluorine-18
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