/

Immunologia e infezioni

/

一种评价金黄色葡萄球菌感染先天免疫反应的小鼠模型

JoVE Journal
Immunologia e infezioni

È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.

JoVE Journal Immunologia e infezioni

A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection

Please note that all translations are automatically generated. Click here for the English version.

一种评价金黄色葡萄球菌感染先天免疫反应的小鼠模型

DOI:

10.3791/59015-v

•

09:15 min

•

February 28, 2019

•

Leif S. Anderson, Mack B. Reynolds, Kathryn R. Rivara, Lloyd S. Miller, Scott I. Simon

¹Department of Biomedical Engineering,University of California Davis, ²Department of Dermatology,Johns Hopkins University School of Medicine

Capitoli

00:04Titolo
00:38Bacterial Preparation and Quantification
02:44Excisional Skin Wounding
03:50Staphylococcus aureus Inoculation
04:44In Vivo Bioluminescent and Fluorescence Imaging
06:02Bioluminescent and Fluorescence Image Analysis
06:45Results: LysM-EGFPMyD88-/- Mice are More Susceptible to S. aureus Infection Than LysM-EGFP Mice
08:30Conclusion

Summary

Traduzione automatica

介绍了一种实时检测小鼠皮肤损伤和金黄色葡萄球菌感染的先天免疫反应的方法。通过将 lysm-egfp 小鼠 (具有荧光中性粒细胞) 与 lysm-egfp 杂交免疫缺陷小鼠株进行比较, 提高了对感染的认识, 并提出了对抗感染的方法。

Tags

Mouse Model Staphylococcus Aureus Infection Innate Immune Response Bioluminescence Bacterial Burden Neutrophil Response Longitudinal Monitoring Excisional Skin Wounding Bacterial Inoculation Colony-forming Units

Article

Embed

AGGIUNGI ALLA PLAYLIST

Usage Statistics

Video correlati

皮下感染耐甲氧西林金黄色葡萄球菌（MRSA）的

寄生蜂简介<em>果蝇</em>和Antiparasite的免疫反应的

耐甲氧西林实验性心内膜炎模型<em>金黄色葡萄球菌</em>（MRSA）的大鼠

呼吸爆发的响应为先天免疫健康的斑马鱼中的指标量化

利用RNA干扰调查的先天免疫反应的小鼠巨噬细胞

在 MyD88的介导的细胞免疫应答西尼罗河病毒变异株感染体外分析

先天免疫反应中的斑马鱼幼体型号无创成像<em>链球菌iniae</em>感染

基因分型<em>金黄色葡萄球菌</em>由核糖体垫片的PCR（RS-PCR）

一种研究食细胞诱导免疫应答的 mellonella 口服液模型

单核细胞分离研究人类粘膜淋巴组织中先天免疫反应

Read Article