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Neuroscience

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JoVE Journal Neuroscience
Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro
 

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro

Article DOI: 10.3791/60044-v • 06:22 min • August 28th, 2019
August 28th, 2019 •
1,2, 3, 4, 1,2
1Discipline of Physiology, Sydney Medical School, University of Sydney, 2Bosch Institute, Sydney Medical School, University of Sydney, 3The MARCS Institute, Western Sydney University, 4Department of Pharmacology, Physiology & Neuroscience, Rutgers Biomedical and Health Sciences

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Galvanic vestibular stimulation in humans exhibits improvements in vestibular function. However, it is unknown how these effects occur. Here, we describe how to apply sinusoidal and stochastic electrical noise and evaluate appropriate stimulus amplitudes in individual medial vestibular nucleus neurons in the C57BL/6 mouse.

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Stochastic Noise Application Assessment Medial Vestibular Nucleus Neuron Sensitivity In Vitro Electrical Noise Individual Neurons Tissue Slices Neuronal Responses Stimulus Parameters Functional Neuronal Types Therapeutics Balance Dysfunction Brainstem Extraction Equilibry S-ACSF CARPOGEN Minus 80 Degrees Celsius Ice Slurry Sagittal Skin Incision Skull C-57 Black Six Mouse Sagittal Suture Pierson Von Jours Parietal And Exoccipital Bones Ice Cold S-ACSF Isolated Brain Stem
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