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Immunology and Infection

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JoVE Journal Immunology and Infection
In vivo augmentatie van gut-homing regulatoire T Cell inductie
 
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In vivo augmentatie van gut-homing regulatoire T Cell inductie

Article DOI: 10.3791/60585-v • 08:02 min • January 22nd, 2020
January 22nd, 2020 •
1,2, 1, 1, 1,3,4, 1,3
1Division of Regenerative Medicine, Department of Medicine, Loma Linda University, 2Zhengzhou University, 3Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, 4Jinan Infectious Disease Hospital, Shandong University

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Hier presenteren we een protocol voor in vivo vergroting van gut-homing regulatoire T Cell inductie. In dit protocol zijn dendritische cellen ontworpen om lokaal hoge concentraties van de actieve vitamine D (1,25-dihydroxyvitamin D of 1,25 [OH]2d) en de actieve vitamine A (retinoïnezuur of RA) de Novo te produceren.

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Immunologie en infectie uitgave 155 gut-homing regulatoire T-cellen 25-hydroxyvitamin D 1α-hydroxylase cytochroom P450 familie 27 subfamilie B lid 1 1 25-dihydroxyvitamin D foxp3 dendritische cellen retinaldehyde dehydrogenase 2 c-c Chemokine receptor Type 9
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