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Developmental Biology
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JoVE Journal Developmental Biology
Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
 

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Article DOI: 10.3791/60600-v • 08:42 min • February 8th, 2020
February 8th, 2020 •
*1,2, *1, 1, 1, 1, 3,4, 1,2, 1,2
1The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for NeuroInformation, University of Electronic Science and Technology of China, 2Sichuan Institute for Brain Science and Brain-inspired Intelligence, 3Department of Electronic Engineering, City University of Hong Kong, 4Centre for Biosystems, Neuroscience, and Nanotechnology, City University of Hong Kong
* These authors contributed equally

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Here, we present detailed protocols for monocular visual deprivation and ocular dominance plasticity analysis, which are important methods for studying the neural mechanisms of visual plasticity during the critical period and the effects of specific genes on visual development.

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Keywords: Monocular Visual Deprivation Ocular Dominance Plasticity Primary Visual Cortex Mouse Binocular Segment Contralateral Eye Ipsilateral Eye Critical Period V1 Neurons Electrophysiological Recording Anesthesia Stereotaxic Frame Craniotomy
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