Rivista
/
/
Gecombineerd gebruik van staart ader metastase assays en real-time in vivo beeldvorming om borstkanker te kwantificeren gemetastaseerde kolonisatie en last in de longen
JoVE Journal
Ricerca sul cancro
È necessario avere un abbonamento a JoVE per visualizzare questo.  Accedi o inizia la tua prova gratuita.
JoVE Journal Ricerca sul cancro
Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
DOI:

10:32 min

December 19, 2019

, ,

Capitoli

  • 00:04Titolo
  • 00:32Generation of Cancer Cells Stably Expressing Luciferase and a Fluorescent Protein
  • 01:59Tail Vein Injection of Labeled Cancer Cells
  • 04:17Monitoring the Metastatic Burden by Bioluminescence with an in vivo Live Animal Imaging Device
  • 06:18Quantification of the Number and Size of Metastases and Analysis of the Imaging Data
  • 08:01Results: YAP and TAZ are Required for Metastatic Colonization and Subsequent Growth of Breast Cancer Cells in Syngeneic Mice
  • 09:36Conclusion

Summary

Traduzione automatica

De beschreven aanpak combineert experimentele staart ader metastase assays met in vivo levende dierlijke beeldvorming zodat real-time monitoring van borstkanker metastase vorming en groei in aanvulling op de kwantificering van metastasen aantal en grootte in de longen.

Video correlati

Read Article