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Journal / Biochemistry / 使用荧光寿命成像在老化C.Elegans中淀粉样蛋白结构的表征…
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Biochemistry

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JoVE Journal Biochemistry
使用荧光寿命成像在老化C.Elegans中淀粉样蛋白结构的表征
 
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使用荧光寿命成像在老化C.Elegans中淀粉样蛋白结构的表征

Article DOI: 10.3791/61004-v • 09:31 min • March 27th, 2020
March 27th, 2020 •
*1,2, *1, *1, 3, 1,4
1Leibniz Research Institute for Molecular Pharmacology im Forschungsverbund Berlin, 2NeuroCure Cluster of Excellence, Charité - Universitätsmedizin Berlin, 3Molecular Neuroscience Group, Department of Chemical Engineering and Biotechnology, University of Cambridge, 4Cell Biology, University of Bremen
* These authors contributed equally

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荧光寿命成像监测器，定量和区分蛋白质在生活、衰老和压力的C.elegans疾病模型中的聚集趋势。

Tags

生物化学， 第 157 期，C. elegans，聚合、 老化、 蛋白酶体网络、 siRNA 击倒、 荧光寿命成像显微镜 （FLIM）、 时间相关的单光子计数 （TCSPC）、 寿命 （tau）
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