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基于微创技术的小鼠挫伤脊髓损伤模型的建立
JoVE Journal
Neuroscienze
This content is Free Access.
JoVE Journal Neuroscienze
Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique
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基于微创技术的小鼠挫伤脊髓损伤模型的建立

DOI:
10.3791/64538-v

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07:17 min

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September 07, 2022

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, , , , ,
1Department of Orthopaedics,Qilu Hospital of Shandong University, 2Department of Orthopaedics,Tianjin Medical University General Hospital

Capitoli

  • 00:05Introduction
  • 01:06Mechanism of the Spinal Cord Injury Coaxial Platform and Mechanical Tests
  • 02:02Locating and Laminectomy of the 9th Thoracic Vertebra (T9)
  • 04:11T9 Contusion Injury
  • 05:23Results: Sagittal Sections on the 1st and 56th Days After Injury to the Spinal Cord of Mice
  • 06:38Conclusion

Summary

Traduzione automatica

Traduzione automatica

微创技术和简单的实验室设备通过减少对实验动物的手术损伤并允许解剖形态维持来提高脊髓损伤模型的可重复性。该方法是值得的，因为可靠的结果和可重复的程序有助于研究疾病修复的机制。

Tags

Keywords: Mouse Contusion Spinal Cord InjuryMinimally Invasive TechniqueAnatomical StructureWeight DropSpinal Cord LocatingLaminectomyParaspinal Muscle DissectionMicroenvironment Analysis

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