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Journal / Bioengineering / 符合GMP的基因修饰T细胞生成程序
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Bioengineering
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JoVE Journal Bioengineering
符合GMP的基因修饰T细胞生成程序
 
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符合GMP的基因修饰T细胞生成程序

Article DOI: 10.3791/65097-v • 06:47 min • October 6th, 2023
October 6th, 2023 •
1, 1, 1, 1, 1, 1, 2, 1
1Institute of Cell Therapy, Bone Marrow Transplantation Lab, Department of Medicine, University of Patras, 2Protatonce Ltd, Demokritos Science Park

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该协议概述了用目标基因转导原代人T细胞的过程，确保与良好生产规范（GMP）标准兼容。

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符合GMP标准的程序，基因修饰T细胞，过继细胞疗法，转基因细胞，CAR-T细胞，血液系统恶性肿瘤，内部制造，质量控制评估，国家和国际监管机构，大规模病毒载体，T细胞转导过程，慢病毒转导，原代人T细胞，荧光标记物，目的基因
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