Alexander Hergovich UCL Cancer Institute Biography Publications Institution JoVE Articles Alexander Hergovich has not added a biography. If you are Alexander Hergovich and would like to personalize this page please email our Author Liaison for assistance. Publications YAP-Hippo Signalling Downstream of Leukemia Inhibitory Factor Receptor: Implications for Breast Cancer Breast Cancer Research : BCR. Dec, 2012 | Pubmed ID: 23216692 Hippo Signalling in the G2/M Cell Cycle Phase: Lessons Learned from the Yeast MEN and SIN Pathways Seminars in Cell & Developmental Biology. Sep, 2012 | Pubmed ID: 22525225 Mammalian Hippo Signalling: a Kinase Network Regulated by Protein-protein Interactions Biochemical Society Transactions. Feb, 2012 | Pubmed ID: 22260677 MICAL-1 is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis Molecular and Cellular Biology. Sep, 2011 | Pubmed ID: 21730291 Downstream of Human NDR Kinases: Impacting on C-myc and P21 Protein Stability to Control Cell Cycle Progression Cell Cycle (Georgetown, Tex.). Jun, 2011 | Pubmed ID: 21593588 MOB Control: Reviewing a Conserved Family of Kinase Regulators Cellular Signalling. Sep, 2011 | Pubmed ID: 21539912 Human NDR Kinases Control G(1)/S Cell Cycle Transition by Directly Regulating P21 Stability Molecular and Cellular Biology. Apr, 2011 | Pubmed ID: 21262772 Differential NDR/LATS Interactions with the Human MOB Family Reveal a Negative Role for Human MOB2 in the Regulation of Human NDR Kinases Molecular and Cellular Biology. Sep, 2010 | Pubmed ID: 20624913 Ablation of the Kinase NDR1 Predisposes Mice to the Development of T Cell Lymphoma Science Signaling. 2010 | Pubmed ID: 20551432 TAZ-mediated Crosstalk Between Wnt and Hippo Signaling Developmental Cell. Apr, 2010 | Pubmed ID: 20412766 The MST1 and HMOB1 Tumor Suppressors Control Human Centrosome Duplication by Regulating NDR Kinase Phosphorylation Current Biology : CB. Nov, 2009 | Pubmed ID: 19836237 VHL Loss Causes Spindle Misorientation and Chromosome Instability Nature Cell Biology. Aug, 2009 | Pubmed ID: 19620968 Mammalian NDR/LATS Protein Kinases in Hippo Tumor Suppressor Signaling BioFactors (Oxford, England). Jul-Aug, 2009 | Pubmed ID: 19484742 Regulation of Renal Epithelial Tight Junctions by the Von Hippel-Lindau Tumor Suppressor Gene Involves Occludin and Claudin 1 and is Independent of E-cadherin Molecular Biology of the Cell. Feb, 2009 | Pubmed ID: 19073886 NDR Kinase is Activated by RASSF1A/MST1 in Response to Fas Receptor Stimulation and Promotes Apoptosis Current Biology : CB. Dec, 2008 | Pubmed ID: 19062280 Nuclear Dbf2-related Protein Kinases (NDRs) in Isolated Cardiac Myocytes and the Myocardium: Activation by Cellular Stresses and by Phosphoprotein Serine-/threonine-phosphatase Inhibitors Cellular Signalling. Aug, 2008 | Pubmed ID: 18555663 Mammalian NDR Protein Kinases: from Regulation to a Role in Centrosome Duplication Biochimica Et Biophysica Acta. Jan, 2008 | Pubmed ID: 17881309 Centrosome-associated NDR Kinase Regulates Centrosome Duplication Molecular Cell. Feb, 2007 | Pubmed ID: 17317633 Priming-dependent Phosphorylation and Regulation of the Tumor Suppressor PVHL by Glycogen Synthase Kinase 3 Molecular and Cellular Biology. Aug, 2006 | Pubmed ID: 16847331 The Human Tumour Suppressor LATS1 is Activated by Human MOB1 at the Membrane Biochemical and Biophysical Research Communications. Jun, 2006 | Pubmed ID: 16674920 NDR Kinases Regulate Essential Cell Processes from Yeast to Humans Nature Reviews. Molecular Cell Biology. Apr, 2006 | Pubmed ID: 16607288 Regulation of NDR Protein Kinase by Hydrophobic Motif Phosphorylation Mediated by the Mammalian Ste20-like Kinase MST3 Molecular and Cellular Biology. Dec, 2005 | Pubmed ID: 16314523 Human NDR Kinases Are Rapidly Activated by MOB Proteins Through Recruitment to the Plasma Membrane and Phosphorylation Molecular and Cellular Biology. Sep, 2005 | Pubmed ID: 16135814 Regulation of NDR2 Protein Kinase by Multi-site Phosphorylation and the S100B Calcium-binding Protein The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 15037617 Relevance of Nuclear and Cytoplasmic Von Hippel Lindau Protein Expression for Renal Carcinoma Progression The American Journal of Pathology. Sep, 2003 | Pubmed ID: 12937142 Regulation of Microtubule Stability by the Von Hippel-Lindau Tumour Suppressor Protein PVHL Nature Cell Biology. Jan, 2003 | Pubmed ID: 12510195 Generering af stabile humane cellelinjer med tetracyklin-inducerbare (Tet-on) shRNA eller cDNA Expression Marta Gomez-Martinez1, Debora Schmitz2, Alexander Hergovich1 1UCL Cancer Institute, 2Friedrich Miescher Institute for Biomedical Research JoVE 50171 생물학
Generering af stabile humane cellelinjer med tetracyklin-inducerbare (Tet-on) shRNA eller cDNA Expression Marta Gomez-Martinez1, Debora Schmitz2, Alexander Hergovich1 1UCL Cancer Institute, 2Friedrich Miescher Institute for Biomedical Research JoVE 50171 생물학