Alexis Rohou Department of Structural Biology Genentech Biography Publications Institution JoVE Articles Alexis Rohou has not added a biography. If you are Alexis Rohou and would like to personalize this page please email our Author Liaison for assistance. Publications Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action Via Cryogenic Electron Microscopy Journal of Medicinal Chemistry. 04, 2021 | Pubmed ID: 33749283 Discovery of a Dual Pathway Aggregation Mechanism for a Therapeutic Constrained Peptide Journal of Pharmaceutical Sciences. 06, 2021 | Pubmed ID: 33652014 Structures of HCMV Trimer Reveal the Basis for Receptor Recognition and Cell Entry Cell. Mar, 2021 | Pubmed ID: 33626330 A TRPA1 Inhibitor Suppresses Neurogenic Inflammation and Airway Contraction for Asthma Treatment The Journal of Experimental Medicine. Apr, 2021 | Pubmed ID: 33620419 Improving Cryo-EM Structure Validation Nature Methods. 02, 2021 | Pubmed ID: 33542515 A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel Neuron. 01, 2021 | Pubmed ID: 33152265 Structure of CD20 in Complex with the Therapeutic Monoclonal Antibody Rituximab Science (New York, N.Y.). 03, 2020 | Pubmed ID: 32079680 Structures of Autoinhibited and Polymerized Forms of CARD9 Reveal Mechanisms of CARD9 and CARD11 Activation Nature Communications. Jul, 2019 | Pubmed ID: 31296852 Structural Basis of α-scorpion Toxin Action on Na Channels Science (New York, N.Y.). 03, 2019 | Pubmed ID: 30733386 Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin Cell. 02, 2019 | Pubmed ID: 30661758 Picomolar Zinc Binding Modulates Formation of Bcl10-nucleating Assemblies of the Caspase Recruitment Domain (CARD) of CARD9 The Journal of Biological Chemistry. 10, 2018 | Pubmed ID: 30206119 gP2S, et informationsstyringssystem til CryoEM-eksperimenter Dorota Wypych1, Daniel Kierecki1, Filip M. Golebiowski1, Alexis Rohou2 1Roche Polska Sp. z o.o., 2Department of Structural Biology, Genentech JoVE 62377 생화학
gP2S, et informationsstyringssystem til CryoEM-eksperimenter Dorota Wypych1, Daniel Kierecki1, Filip M. Golebiowski1, Alexis Rohou2 1Roche Polska Sp. z o.o., 2Department of Structural Biology, Genentech JoVE 62377 생화학