Alexis Rohou Department of Structural Biology Genentech Biography Publications Institution JoVE Articles Alexis Rohou has not added a biography. If you are Alexis Rohou and would like to personalize this page please email our Author Liaison for assistance. Publications Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action Via Cryogenic Electron Microscopy Journal of Medicinal Chemistry. 04, 2021 | Pubmed ID: 33749283 Discovery of a Dual Pathway Aggregation Mechanism for a Therapeutic Constrained Peptide Journal of Pharmaceutical Sciences. 06, 2021 | Pubmed ID: 33652014 Structures of HCMV Trimer Reveal the Basis for Receptor Recognition and Cell Entry Cell. Mar, 2021 | Pubmed ID: 33626330 A TRPA1 Inhibitor Suppresses Neurogenic Inflammation and Airway Contraction for Asthma Treatment The Journal of Experimental Medicine. Apr, 2021 | Pubmed ID: 33620419 Improving Cryo-EM Structure Validation Nature Methods. 02, 2021 | Pubmed ID: 33542515 A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel Neuron. 01, 2021 | Pubmed ID: 33152265 Structure of CD20 in Complex with the Therapeutic Monoclonal Antibody Rituximab Science (New York, N.Y.). 03, 2020 | Pubmed ID: 32079680 Structures of Autoinhibited and Polymerized Forms of CARD9 Reveal Mechanisms of CARD9 and CARD11 Activation Nature Communications. Jul, 2019 | Pubmed ID: 31296852 Structural Basis of α-scorpion Toxin Action on Na Channels Science (New York, N.Y.). 03, 2019 | Pubmed ID: 30733386 Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin Cell. 02, 2019 | Pubmed ID: 30661758 Picomolar Zinc Binding Modulates Formation of Bcl10-nucleating Assemblies of the Caspase Recruitment Domain (CARD) of CARD9 The Journal of Biological Chemistry. 10, 2018 | Pubmed ID: 30206119 gP2S, un sistema di gestione delle informazioni per gli esperimenti CryoEM Dorota Wypych1, Daniel Kierecki1, Filip M. Golebiowski1, Alexis Rohou2 1Roche Polska Sp. z o.o., 2Department of Structural Biology, Genentech JoVE 62377 생화학
gP2S, un sistema di gestione delle informazioni per gli esperimenti CryoEM Dorota Wypych1, Daniel Kierecki1, Filip M. Golebiowski1, Alexis Rohou2 1Roche Polska Sp. z o.o., 2Department of Structural Biology, Genentech JoVE 62377 생화학