Alyssa H. Hasty Department of Molecular Physiology and Biophysics Vanderbilt University School of Medicine Biography Publications Institution JoVE Articles Alyssa H. Hasty has not added a biography. If you are Alyssa H. Hasty and would like to personalize this page please email our Author Liaison for assistance. Publications Endoplasmic Reticulum Stress and Hypertension - a New Paradigm? The Journal of Clinical Investigation. Nov, 2012 | Pubmed ID: 23064369 Toll-like Receptor 4 Deficiency Promotes the Alternative Activation of Adipose Tissue Macrophages Diabetes. Nov, 2012 | Pubmed ID: 22751700 Stearic Acid Accumulation in Macrophages Induces Toll-like Receptor 4/2-independent Inflammation Leading to Endoplasmic Reticulum Stress-mediated Apoptosis Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2012 | Pubmed ID: 22556332 Impact of Macrophage Inflammatory Protein-1α Deficiency on Atherosclerotic Lesion Formation, Hepatic Steatosis, and Adipose Tissue Expansion PloS One. 2012 | Pubmed ID: 22359597 Haematopoietic Leptin Receptor Deficiency Does Not Affect Macrophage Accumulation in Adipose Tissue or Systemic Insulin Sensitivity The Journal of Endocrinology. Mar, 2012 | Pubmed ID: 22194312 Aberrant Accumulation of Undifferentiated Myeloid Cells in the Adipose Tissue of CCR2-deficient Mice Delays Improvements in Insulin Sensitivity Diabetes. Nov, 2011 | Pubmed ID: 21926275 The Role of Adipose Tissue in Mediating the Beneficial Effects of Dietary Fish Oil The Journal of Nutritional Biochemistry. Feb, 2011 | Pubmed ID: 21145721 Absence of Macrophage Inflammatory Protein-1{alpha} Does Not Impact Macrophage Accumulation in Adipose Tissue of Diet-induced Obese Mice American Journal of Physiology. Endocrinology and Metabolism. Sep, 2010 | Pubmed ID: 20551286 Adipose Tissue Recruitment of Leukocytes Current Opinion in Lipidology. Jun, 2010 | Pubmed ID: 20410821 Mouse Models of the Metabolic Syndrome Disease Models & Mechanisms. Mar-Apr, 2010 | Pubmed ID: 20212084 Nitro-fatty Acids Reduce Atherosclerosis in Apolipoprotein E-deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2010 | Pubmed ID: 20167658 The Role of Chemokines in Recruitment of Immune Cells to the Artery Wall and Adipose Tissue Vascular Pharmacology. Jan-Feb, 2010 | Pubmed ID: 20026286 Dietary Fish Oil Exerts Hypolipidemic Effects in Lean and Insulin Sensitizing Effects in Obese LDLR-/- Mice The Journal of Nutrition. Dec, 2009 | Pubmed ID: 19864403 Defective Phagocytosis of Apoptotic Cells by Macrophages in Atherosclerotic Lesions of Ob/ob Mice and Reversal by a Fish Oil Diet Circulation Research. Nov, 2009 | Pubmed ID: 19834009 Inhibition of Long-chain Acyl Coenzyme A Synthetases During Fatty Acid Loading Induces Lipotoxicity in Macrophages Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2009 | Pubmed ID: 19679826 Loss of Ovarian Function in the VCD Mouse-model of Menopause Leads to Insulin Resistance and a Rapid Progression into the Metabolic Syndrome American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2009 | Pubmed ID: 19439618 Impact of Increased Adipose Tissue Mass on Inflammation, Insulin Resistance, and Dyslipidemia Current Diabetes Reports. Feb, 2009 | Pubmed ID: 19192421 Lipid and Phospholipid Profiling of Biological Samples Using MALDI Fourier Transform Mass Spectrometry Lipids. Apr, 2009 | Pubmed ID: 19005715 Macrophage Infiltration into Adipose Tissue: Initiation, Propagation and Remodeling Future Lipidology. 2008 | Pubmed ID: 18978945 Palmitate Impairs and Eicosapentaenoate Restores Insulin Secretion Through Regulation of SREBP-1c in Pancreatic Islets Diabetes. Sep, 2008 | Pubmed ID: 18458149 Cyclin-dependent Kinase Inhibitor, P21WAF1/CIP1, is Involved in Adipocyte Differentiation and Hypertrophy, Linking to Obesity, and Insulin Resistance The Journal of Biological Chemistry. Jul, 2008 | Pubmed ID: 18445590 Central Nervous System Neuropeptide Y Signaling Modulates VLDL Triglyceride Secretion Diabetes. Jun, 2008 | Pubmed ID: 18332095 Atherosclerotic Lesion Formation and Triglyceride Storage in Obese Apolipoprotein AI-deficient Mice The Journal of Nutritional Biochemistry. Oct, 2008 | Pubmed ID: 18280133 The Role of Macrophage Leptin Receptor in Aortic Root Lesion Formation American Journal of Physiology. Endocrinology and Metabolism. Mar, 2008 | Pubmed ID: 18182468 Macrophage-derived Apolipoprotein E Ameliorates Dyslipidemia and Atherosclerosis in Obese Apolipoprotein E-deficient Mice American Journal of Physiology. Endocrinology and Metabolism. Feb, 2008 | Pubmed ID: 18029445 Crucial Role of a Long-chain Fatty Acid Elongase, Elovl6, in Obesity-induced Insulin Resistance Nature Medicine. Oct, 2007 | Pubmed ID: 17906635 Carbenoxolone Treatment Attenuates Symptoms of Metabolic Syndrome and Atherogenesis in Obese, Hyperlipidemic Mice American Journal of Physiology. Endocrinology and Metabolism. Dec, 2007 | Pubmed ID: 17878220 Leptin Requires Canonical Migratory Signaling Pathways for Induction of Monocyte and Macrophage Chemotaxis American Journal of Physiology. Cell Physiology. Nov, 2007 | Pubmed ID: 17728393 Fish Oil Increases Cholesterol Storage in White Adipose Tissue with Concomitant Decreases in Inflammation, Hepatic Steatosis, and Atherosclerosis in Mice The Journal of Nutrition. Jul, 2007 | Pubmed ID: 17585030 Direct Effect of Cholesterol on Insulin Secretion: a Novel Mechanism for Pancreatic Beta-cell Dysfunction Diabetes. Sep, 2007 | Pubmed ID: 17575085 Obesity Potentiates Development of Fatty Liver and Insulin Resistance, but Not Atherosclerosis, in High-fat Diet-fed Agouti LDLR-deficient Mice American Journal of Physiology. Endocrinology and Metabolism. Aug, 2007 | Pubmed ID: 17566116 Obesity Causes Very Low Density Lipoprotein Clearance Defects in Low-density Lipoprotein Receptor-deficient Mice The Journal of Nutritional Biochemistry. Nov, 2007 | Pubmed ID: 17418556 Diet-induced Increases in Adiposity, but Not Plasma Lipids, Promote Macrophage Infiltration into White Adipose Tissue Diabetes. Mar, 2007 | Pubmed ID: 17327423 Effects of Vitamin E on Oxidative Stress and Atherosclerosis in an Obese Hyperlipidemic Mouse Model The Journal of Nutritional Biochemistry. Feb, 2007 | Pubmed ID: 16781857 Deletion of the Gene Encoding the Ubiquitously Expressed Glucose-6-phosphatase Catalytic Subunit-related Protein (UGRP)/glucose-6-phosphatase Catalytic Subunit-beta Results in Lowered Plasma Cholesterol and Elevated Glucagon The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 17023421 Granuphilin is Activated by SREBP-1c and Involved in Impaired Insulin Secretion in Diabetic Mice Cell Metabolism. Aug, 2006 | Pubmed ID: 16890542 The Role of Lipolysis in Mediating the Proinflammatory Effects of Very Low Density Lipoproteins in Mouse Peritoneal Macrophages Journal of Lipid Research. Jul, 2006 | Pubmed ID: 16639077 Quantitation and Cellular Localization of 11beta-HSD1 Expression in Murine Thymus The Journal of Steroid Biochemistry and Molecular Biology. May, 2006 | Pubmed ID: 16621520 Intracellular Trafficking of Recycling Apolipoprotein E in Chinese Hamster Ovary Cells Journal of Lipid Research. Jun, 2006 | Pubmed ID: 16534141 TFE3 Transcriptionally Activates Hepatic IRS-2, Participates in Insulin Signaling and Ameliorates Diabetes Nature Medicine. Jan, 2006 | Pubmed ID: 16327801 Plasminogen Activator Inhibitor-1 Modulates Adipocyte Differentiation American Journal of Physiology. Endocrinology and Metabolism. Jan, 2006 | Pubmed ID: 16144810 Plasma Insulin Levels Predict Atherosclerotic Lesion Burden in Obese Hyperlipidemic Mice Atherosclerosis. May, 2006 | Pubmed ID: 16102772 Physiological Relevance of Apolipoprotein E Recycling: Studies in Primary Mouse Hepatocytes Metabolism: Clinical and Experimental. Oct, 2005 | Pubmed ID: 16154429 Persistence of High Density Lipoprotein Particles in Obese Mice Lacking Apolipoprotein A-I Journal of Lipid Research. Sep, 2005 | Pubmed ID: 15995171 Recombinant Leptin Promotes Atherosclerosis and Thrombosis in Apolipoprotein E-deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2005 | Pubmed ID: 15947243 Reduced ABCA1-mediated Cholesterol Efflux and Accelerated Atherosclerosis in Apolipoprotein E-deficient Mice Lacking Macrophage-derived ACAT1 Circulation. May, 2005 | Pubmed ID: 15851589 The Recycling of Apolipoprotein E in Macrophages: Influence of HDL and Apolipoprotein A-I Journal of Lipid Research. Jul, 2005 | Pubmed ID: 15805547 Macrophage Apolipoprotein A-I Expression Protects Against Atherosclerosis in ApoE-deficient Mice and Up-regulates ABC Transporters Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2003 | Pubmed ID: 14529830 Cross-talk Between Peroxisome Proliferator-activated Receptor (PPAR) Alpha and Liver X Receptor (LXR) in Nutritional Regulation of Fatty Acid Metabolism. I. PPARs Suppress Sterol Regulatory Element Binding Protein-1c Promoter Through Inhibition of LXR Signaling Molecular Endocrinology (Baltimore, Md.). Jul, 2003 | Pubmed ID: 12730331 Hepatocyte-derived ApoE is More Effective Than Non-hepatocyte-derived ApoE in Remnant Lipoprotein Clearance The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12551940 The Recycling of Apolipoprotein E in Primary Cultures of Mouse Hepatocytes. Evidence for a Physiologic Connection to High Density Lipoprotein Metabolism The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12524433 Physiological Expression of Macrophage ApoE in the Artery Wall Reduces Atherosclerosis in Severely Hyperlipidemic Mice Journal of Lipid Research. Oct, 2002 | Pubmed ID: 12364544 Transcriptional Activities of Nuclear SREBP-1a, -1c, and -2 to Different Target Promoters of Lipogenic and Cholesterogenic Genes Journal of Lipid Research. Aug, 2002 | Pubmed ID: 12177166 Cloning and Characterization of a Mammalian Fatty Acyl-CoA Elongase As a Lipogenic Enzyme Regulated by SREBPs Journal of Lipid Research. Jun, 2002 | Pubmed ID: 12032166 Absence of Sterol Regulatory Element-binding Protein-1 (SREBP-1) Ameliorates Fatty Livers but Not Obesity or Insulin Resistance in Lep(ob)/Lep(ob) Mice The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11923308 Dual Regulation of Mouse Delta(5)- and Delta(6)-desaturase Gene Expression by SREBP-1 and PPARalpha Journal of Lipid Research. Jan, 2002 | Pubmed ID: 11792729 Изоляция жировой ткани иммунных клеток Jeb S. Orr1, Arion J. Kennedy1, Alyssa H. Hasty1 1Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine JoVE 50707 면역학 및 감염병학
Изоляция жировой ткани иммунных клеток Jeb S. Orr1, Arion J. Kennedy1, Alyssa H. Hasty1 1Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine JoVE 50707 면역학 및 감염병학