Andrew Wolfe Department of Pediatrics Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Andrew Wolfe has not added a biography. If you are Andrew Wolfe and would like to personalize this page please email our Author Liaison for assistance. Publications Multiplex Quantification Identifies Novel Exercise-regulated Myokines/Cytokines in Plasma and in Glycolytic and Oxidative Skeletal Muscle Molecular & Cellular Proteomics : MCP. Aug, 2018 | Pubmed ID: 29735541 Hepatic Estrogen Receptor α is Critical for Regulation of Gluconeogenesis and Lipid Metabolism in Males Scientific Reports. May, 2017 | Pubmed ID: 28490809 Aging and Estradiol Effects on Gene Expression in the Medial Preoptic Area, Bed Nucleus of the Stria Terminalis, and Posterodorsal Medial Amygdala of Male Rats Molecular and Cellular Endocrinology. 02, 2017 | Pubmed ID: 28007657 Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction Via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms Endocrinology. 03, 2017 | Pubmed ID: 27967242 Adverse Reproductive and Developmental Health Outcomes Following Prenatal Exposure to a Hydraulic Fracturing Chemical Mixture in Female C57Bl/6 Mice Endocrinology. 09, 2016 | Pubmed ID: 27560547 Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice PloS One. 2016 | Pubmed ID: 27441639 The Methylcytosine Dioxygenase Ten-Eleven Translocase-2 (tet2) Enables Elevated GnRH Gene Expression and Maintenance of Male Reproductive Function Endocrinology. 09, 2016 | Pubmed ID: 27384303 Estradiol Restrains Prepubertal Gonadotropin Secretion in Female Mice Via Activation of ERα in Kisspeptin Neurons Endocrinology. Apr, 2016 | Pubmed ID: 26824364 Maternal Vitamin D Deficiency Programs Reproductive Dysfunction in Female Mice Offspring Through Adverse Effects on the Neuroendocrine Axis Endocrinology. Apr, 2016 | Pubmed ID: 26741195 Testing the Critical Window Hypothesis of Timing and Duration of Estradiol Treatment on Hypothalamic Gene Networks in Reproductively Mature and Aging Female Rats Endocrinology. Aug, 2015 | Pubmed ID: 26018250 Substance P Regulates Puberty Onset and Fertility in the Female Mouse Endocrinology. Jun, 2015 | Pubmed ID: 25856429 Developmental and Endocrine Regulation of Kisspeptin Expression in Mouse Leydig Cells Endocrinology. Apr, 2015 | Pubmed ID: 25635620 Positive, but Not Negative Feedback Actions of Estradiol in Adult Female Mice Require Estrogen Receptor α in Kisspeptin Neurons Endocrinology. Mar, 2015 | Pubmed ID: 25545386 Dynamic and Extensive Metabolic State-dependent Regulation of Cytokine Expression and Circulating Levels American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2014 | Pubmed ID: 25320344 The Regulation of Reproductive Neuroendocrine Function by Insulin and Insulin-like Growth Factor-1 (IGF-1) Frontiers in Neuroendocrinology. Oct, 2014 | Pubmed ID: 24929098 Hypothalamic Molecular Changes Underlying Natural Reproductive Senescence in the Female Rat Endocrinology. Sep, 2014 | Pubmed ID: 24914937 Glucagon Regulates Hepatic Kisspeptin to Impair Insulin Secretion Cell Metabolism. Apr, 2014 | Pubmed ID: 24703698 Disrupted Kisspeptin Signaling in GnRH Neurons Leads to Hypogonadotrophic Hypogonadism Molecular Endocrinology (Baltimore, Md.). Feb, 2014 | Pubmed ID: 24422632 Obesity-induced Infertility and Hyperandrogenism Are Corrected by Deletion of the Insulin Receptor in the Ovarian Theca Cell Diabetes. Apr, 2014 | Pubmed ID: 24379345 Gene Therapy to Prolong Reproductive Life Endocrinology. Jun, 2013 | Pubmed ID: 23687112 A Low-copy-number Plasmid for Retrieval of Toxic Genes from BACs and Generation of Conditional Targeting Constructs Molecular Biotechnology. Jun, 2013 | Pubmed ID: 22945876 Estrogenic Regulation of the GnRH Neuron Frontiers in Endocrinology. 2012 | Pubmed ID: 22654870 CREB Binding Protein (CBP) Activation is Required for Luteinizing Hormone Beta Expression and Normal Fertility in Mice Molecular and Cellular Biology. Jul, 2012 | Pubmed ID: 22508984 Estrogen Receptor-β in the Gonadotropin-releasing Hormone Neuron Seminars in Reproductive Medicine. Jan, 2012 | Pubmed ID: 22271291 Signaling of Cytokines is Important in Regulation of GnRH Neurons Molecular Neurobiology. Feb, 2012 | Pubmed ID: 22161498 Reproductive Tissues Maintain Insulin Sensitivity in Diet-induced Obesity Diabetes. Jan, 2012 | Pubmed ID: 22076926 Loss of Epithelial Oestrogen Receptor α Inhibits Oestrogen-stimulated Prostate Proliferation and Squamous Metaplasia Via in Vivo Tissue Selective Knockout Models The Journal of Pathology. Jan, 2012 | Pubmed ID: 22069040 Deletion of Otx2 in GnRH Neurons Results in a Mouse Model of Hypogonadotropic Hypogonadism Molecular Endocrinology (Baltimore, Md.). May, 2011 | Pubmed ID: 21436260 The Gonadotropin-releasing Hormone Cell-specific Element is Required for Normal Puberty and Estrous Cyclicity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2011 | Pubmed ID: 21368045 Jak2 is Necessary for Neuroendocrine Control of Female Reproduction The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2011 | Pubmed ID: 21209203 Rescue of Obesity-induced Infertility in Female Mice Due to a Pituitary-specific Knockout of the Insulin Receptor Cell Metabolism. Sep, 2010 | Pubmed ID: 20816095 Kisspeptin Increases GnRH MRNA Expression and Secretion in GnRH Secreting Neuronal Cell Lines Molecular and Cellular Endocrinology. Nov, 2009 | Pubmed ID: 19576263 Impaired Estrogen Feedback and Infertility in Female Mice with Pituitary-specific Deletion of Estrogen Receptor Alpha (ESR1) Biology of Reproduction. Sep, 2009 | Pubmed ID: 19439729 Estrogen Regulation of Gene Expression in GnRH Neurons Molecular and Cellular Endocrinology. May, 2009 | Pubmed ID: 19428988 Generation and Characterization of a Complete Null Estrogen Receptor Alpha Mouse Using Cre/LoxP Technology Molecular and Cellular Biochemistry. Jan, 2009 | Pubmed ID: 18953638 Development of an Immortalised, Post-pubertal Gonadotrophin-releasing Hormone Neuronal Cell Line Journal of Neuroendocrinology. Sep, 2008 | Pubmed ID: 18624926 Temporal and Spatial Regulation of CRE Recombinase Expression in Gonadotrophin-releasing Hormone Neurones in the Mouse Journal of Neuroendocrinology. Jul, 2008 | Pubmed ID: 18445125 A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome Ping Xue1, Zhiqiang Wang1, Xiaomin Fu1,2, Junjiang Wang1,3, Gopika Punchhi1, Andrew Wolfe1,4, Sheng Wu1,4,5 1Department of Pediatrics, Johns Hopkins University School of Medicine, 2Department of Health, Beijing Military General Hospital, 3Southern Medical University, 4Department of Molecular and Cellular Physiology, Johns Hopkins University School of Medicine, 5Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine JoVE 58379 발생학
A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome Ping Xue1, Zhiqiang Wang1, Xiaomin Fu1,2, Junjiang Wang1,3, Gopika Punchhi1, Andrew Wolfe1,4, Sheng Wu1,4,5 1Department of Pediatrics, Johns Hopkins University School of Medicine, 2Department of Health, Beijing Military General Hospital, 3Southern Medical University, 4Department of Molecular and Cellular Physiology, Johns Hopkins University School of Medicine, 5Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine JoVE 58379 발생학