Branden S. Moriarity Department of Pediatrics University of Minnesota Biography Publications Institution JoVE Articles Branden S. Moriarity has not added a biography. If you are Branden S. Moriarity and would like to personalize this page please email our Author Liaison for assistance. Publications C-to-U RNA Editing: From Computational Detection to Experimental Validation Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 32729074 The S-phase-induced LncRNA Promotes Cell Proliferation by Controlling YAP1/Hippo Signaling Pathway ELife. 10, 2020 | Pubmed ID: 33108271 Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-induced PI3K-AKT Signaling for the Treatment of Metastatic Osteosarcoma Molecular Cancer Therapeutics. Sep, 2020 | Pubmed ID: 32999043 Efficient Targeted Integration Directed by Short Homology in Zebrafish and Mammalian Cells ELife. May, 2020 | Pubmed ID: 32412410 PLX3397 Treatment Inhibits Constitutive CSF1R-induced Oncogenic ERK Signaling, Reduces Tumor Growth, and Metastatic Burden in Osteosarcoma Bone. Jul, 2020 | Pubmed ID: 32251854 CRISPR/Cas9-Mediated Genome Engineering of Primary Human B Cells Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 32006415 A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy Molecular Therapy : the Journal of the American Society of Gene Therapy. 01, 2020 | Pubmed ID: 31704085 SEMA4C is a Novel Target to Limit Osteosarcoma Growth, Progression, and Metastasis Oncogene. Jan, 2020 | Pubmed ID: 31582836 Author Correction: Highly Efficient Multiplex Human T Cell Engineering Without Double-strand Breaks Using Cas9 Base Editors Nature Communications. Dec, 2019 | Pubmed ID: 31811147 Highly Efficient Multiplex Human T Cell Engineering Without Double-strand Breaks Using Cas9 Base Editors Nature Communications. 11, 2019 | Pubmed ID: 31745080 Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis Cell Stem Cell. 09, 2019 | Pubmed ID: 31204176 HBx-K130M/V131I Promotes Liver Cancer in Transgenic Mice Via AKT/FOXO1 Signaling Pathway and Arachidonic Acid Metabolism Molecular Cancer Research : MCR. 07, 2019 | Pubmed ID: 30975706 Identification of Candidate Neoantigens Produced by Fusion Transcripts in Human Osteosarcomas Scientific Reports. 01, 2019 | Pubmed ID: 30674975 Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors Cancer Research. 03, 2019 | Pubmed ID: 30674530 Cancer Gene Discovery Utilizing Sleeping Beauty Transposon Mutagenesis Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30542999 Screen Identifies and Other Genetic Drivers in Human B-cell Lymphoma Molecular Cancer Research : MCR. 02, 2019 | Pubmed ID: 30355676 EditR: A Method to Quantify Base Editing from Sanger Sequencing The CRISPR Journal. 06, 2018 | Pubmed ID: 31021262 Highly Multiplexed Genome Engineering Using CRISPR/Cas9 GRNA Arrays PloS One. 2018 | Pubmed ID: 30222773 The Molecular Imaging of Natural Killer Cells Molecular Imaging. Jan-Dec, 2018 | Pubmed ID: 30203710 Engineering of Primary Human B Cells with CRISPR/Cas9 Targeted Nuclease Scientific Reports. 08, 2018 | Pubmed ID: 30108345 Human IPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity Cell Stem Cell. Aug, 2018 | Pubmed ID: 30082067 CRISPR/Cas9 Library Screening for Drug Target Discovery Journal of Human Genetics. Feb, 2018 | Pubmed ID: 29158600 Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma Cancer Research. 01, 2018 | Pubmed ID: 29066513 Rapid Generation of Col7a1 Mouse Model of Recessive Dystrophic Epidermolysis Bullosa and Partial Rescue Via Immunosuppressive Dermal Mesenchymal Stem Cells Laboratory Investigation; a Journal of Technical Methods and Pathology. 10, 2017 | Pubmed ID: 28892093 Prosurvival Long Noncoding RNA Regulates a Subset of P53 Targets in Human Colorectal Cancer Cells by Binding to Matrin 3 ELife. 06, 2017 | Pubmed ID: 28580901 Relative Importance of β- and γ-actin in Primary Mouse Embryonic Fibroblasts Molecular Biology of the Cell. Mar, 2017 | Pubmed ID: 28077619 A Novel Role for SALL4 During Scar-free Wound Healing in Axolotl NPJ Regenerative Medicine. 2016 | Pubmed ID: 28955504 Slit-Robo GTPase-Activating Protein 2 As a Metastasis Suppressor in Osteosarcoma Scientific Reports. 12, 2016 | Pubmed ID: 27966608 Using Genome-wide CRISPR Library Screening with Library Resistant DCK to Find New Sources of Ara-C Drug Resistance in AML Scientific Reports. 11, 2016 | Pubmed ID: 27808171 RALB Provides Critical Survival Signals Downstream of Ras in Acute Myeloid Leukemia Oncotarget. 10, 2016 | Pubmed ID: 27556501 MTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation Via PRAS40 to Prevent Accumulation of Protein Stress Molecular Cell. Feb, 2016 | Pubmed ID: 26876939 RNA Sequencing of Sleeping Beauty Transposon-induced Tumors Detects Transposon-RNA Fusions in Forward Genetic Cancer Screens Genome Research. Jan, 2016 | Pubmed ID: 26553456 Coping with Cancer Genes Altered by Copy Number Oncotarget. Nov, 2015 | Pubmed ID: 26577648 Transposon Mouse Models to Elucidate the Genetic Mechanisms of Hepatitis B Viral Induced Hepatocellular Carcinoma World Journal of Gastroenterology. Nov, 2015 | Pubmed ID: 26576100 A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma Cancer Discovery. Sep, 2015 | Pubmed ID: 26084801 Sleeping Beauty Transposon Insertional Mutagenesis Based Mouse Models for Cancer Gene Discovery Current Opinion in Genetics & Development. Feb, 2015 | Pubmed ID: 26051241 A Sleeping Beauty Forward Genetic Screen Identifies New Genes and Pathways Driving Osteosarcoma Development and Metastasis Nature Genetics. Jun, 2015 | Pubmed ID: 25961939 Using RNA-seq and Targeted Nucleases to Identify Mechanisms of Drug Resistance in Acute Myeloid Leukemia Scientific Reports. Aug, 2014 | Pubmed ID: 25116387 PVT1 Dependence in Cancer with MYC Copy-number Increase Nature. Aug, 2014 | Pubmed ID: 25043044 HomeRun Vector Assembly System: a Flexible and Standardized Cloning System for Assembly of Multi-modular DNA Constructs PloS One. 2014 | Pubmed ID: 24959875 Trp53 Haploinsufficiency Modifies EGFR-driven Peripheral Nerve Sheath Tumorigenesis The American Journal of Pathology. Jul, 2014 | Pubmed ID: 24832557 Simple and Efficient Methods for Enrichment and Isolation of Endonuclease Modified Cells PloS One. 2014 | Pubmed ID: 24798371 Forward Genetic Screen for Malignant Peripheral Nerve Sheath Tumor Formation Identifies New Genes and Pathways Driving Tumorigenesis Nature Genetics. Jul, 2013 | Pubmed ID: 23685747 Canonical Wnt/β-catenin Signaling Drives Human Schwann Cell Transformation, Progression, and Tumor Maintenance Cancer Discovery. Jun, 2013 | Pubmed ID: 23535903 Modular Assembly of Transposon Integratable Multigene Vectors Using RecWay Assembly Nucleic Acids Research. Apr, 2013 | Pubmed ID: 23444141 Sex Bias Occurrence of Hepatocellular Carcinoma in Poly7 Molecular Subclass is Associated with EGFR Hepatology (Baltimore, Md.). Jan, 2013 | Pubmed ID: 22899566 Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST Sarcoma. 2012 | Pubmed ID: 23319880 Efficient Non-viral Integration and Stable Gene Expression in Multipotent Adult Progenitor Cells Stem Cells International. 2011 | Pubmed ID: 21977042 CRISPR/Cas9を用いた初等ヒトB細胞のゲノム工学 Kanut Laoharawee1,2,3, Matthew J. Johnson1,2,3, Walker S. Lahr1,2,3, Joseph J. Peterson1,2,3, Beau R. Webber1,2,3, Branden S. Moriarity1,2,3 1Department of Pediatrics, University of Minnesota, 2Center for Genomic Engineering, University of Minnesota, 3Masonic Cancer Center, University of Minnesota JoVE 61855 생물학
CRISPR/Cas9を用いた初等ヒトB細胞のゲノム工学 Kanut Laoharawee1,2,3, Matthew J. Johnson1,2,3, Walker S. Lahr1,2,3, Joseph J. Peterson1,2,3, Beau R. Webber1,2,3, Branden S. Moriarity1,2,3 1Department of Pediatrics, University of Minnesota, 2Center for Genomic Engineering, University of Minnesota, 3Masonic Cancer Center, University of Minnesota JoVE 61855 생물학