Caius G. Radu Department of Medical and Molecular Pharmacology David Geffen School of Medicine at UCLA Biography Publications Institution JoVE Articles Caius G. Radu has not added a biography. If you are Caius G. Radu and would like to personalize this page please email our Author Liaison for assistance. Publications Nucleoside Salvage Pathway Kinases Regulate Hematopoiesis by Linking Nucleotide Metabolism with Replication Stress The Journal of Experimental Medicine. Nov, 2012 | Pubmed ID: 23148236 In Vivo Imaging of Therapy-induced Anti-cancer Immune Responses in Humans Cellular and Molecular Life Sciences : CMLS. Oct, 2012 | Pubmed ID: 23052208 Positron Emission Tomography Reporter Genes and Reporter Probes: Gene and Cell Therapy Applications Theranostics. 2012 | Pubmed ID: 22509201 Stratification of Nucleoside Analog Chemotherapy Using 1-(2'-deoxy-2'-18F-fluoro-β-D-arabinofuranosyl)cytosine and 1-(2'-deoxy-2'-18F-fluoro-β-L-arabinofuranosyl)-5-methylcytosine PET Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2012 | Pubmed ID: 22302964 Structure-guided Engineering of Human Thymidine Kinase 2 As a Positron Emission Tomography Reporter Gene for Enhanced Phosphorylation of Non-natural Thymidine Analog Reporter Probe The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22074768 Antitumor Activity from Antigen-specific CD8 T Cells Generated in Vivo from Genetically Engineered Human Hematopoietic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22123951 A Clinical Microchip for Evaluation of Single Immune Cells Reveals High Functional Heterogeneity in Phenotypically Similar T Cells Nature Medicine. Jun, 2011 | Pubmed ID: 21602800 Clustered Arg-Gly-Asp Peptides Enhances Tumor Targeting of Nonviral Vectors ChemMedChem. Apr, 2011 | Pubmed ID: 21442757 Human Biodistribution and Radiation Dosimetry of Novel PET Probes Targeting the Deoxyribonucleoside Salvage Pathway European Journal of Nuclear Medicine and Molecular Imaging. Apr, 2011 | Pubmed ID: 21127859 Kinetic Phases of Distribution and Tumor Targeting by T Cell Receptor Engineered Lymphocytes Inducing Robust Antitumor Responses Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20624956 Novel PET Probes Specific for Deoxycytidine Kinase Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2010 | Pubmed ID: 20554721 Imaging Adoptive Cell Transfer Based Cancer Immunotherapy Current Pharmaceutical Biotechnology. Sep, 2010 | Pubmed ID: 20497110 PET Probes for Distinct Metabolic Pathways Have Different Cell Specificities During Immune Responses in Mice The Journal of Clinical Investigation. Jun, 2010 | Pubmed ID: 20484820 Targeting Leukemia Stem Cells Nature Biotechnology. Mar, 2010 | Pubmed ID: 20212485 Requirement for Deoxycytidine Kinase in T and B Lymphocyte Development Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20080663 AMPK: A Metabolic Checkpoint That Regulates the Growth of EGFR Activated Glioblastomas Cell Cycle (Georgetown, Tex.). Jan, 2010 | Pubmed ID: 20023392 Visualizing Cancer and Immune Cell Function with Metabolic Positron Emission Tomography Current Opinion in Genetics & Development. Feb, 2010 | Pubmed ID: 19931447 Eosinophil Viability is Increased by Acidic PH in a CAMP- and GPR65-dependent Manner Blood. Sep, 2009 | Pubmed ID: 19641187 The AMPK Agonist AICAR Inhibits the Growth of EGFRvIII-expressing Glioblastomas by Inhibiting Lipogenesis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19625624 Modular Nucleic Acid Assembled P/MHC Microarrays for Multiplexed Sorting of Antigen-specific T Cells Journal of the American Chemical Society. Jul, 2009 | Pubmed ID: 19552409 A Supramolecular Approach for Preparation of Size-controlled Nanoparticles Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19425037 Noninvasive Prediction of Tumor Responses to Gemcitabine Using Positron Emission Tomography Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19196993 Integrated Microfluidic Devices for Combinatorial Cell-based Assays Biomedical Microdevices. Jun, 2009 | Pubmed ID: 19130244 Quantitative PET Reporter Gene Imaging of CD8+ T Cells Specific for a Melanoma-expressed Self-antigen International Immunology. Feb, 2009 | Pubmed ID: 19106231 Molecular Imaging of Lymphoid Organs and Immune Activation by Positron Emission Tomography with a New [18F]-labeled 2'-deoxycytidine Analog Nature Medicine. Jul, 2008 | Pubmed ID: 18542051 PET Imaging of Cancer Immunotherapy Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2008 | Pubmed ID: 18511842 Non-invasive Imaging of Adaptive Immunity Using Positron Emission Tomography Immunological Reviews. Feb, 2008 | Pubmed ID: 18275485 Anti-tumor Activity and Trafficking of Self, Tumor-specific T Cells Against Tumors Located in the Brain Cancer Immunology, Immunotherapy : CII. Sep, 2008 | Pubmed ID: 18253732 Migration to Apoptotic "find-me" Signals is Mediated Via the Phagocyte Receptor G2A The Journal of Biological Chemistry. Feb, 2008 | Pubmed ID: 18089568 Sustained Suppression of Bcr-Abl-driven Lymphoid Leukemia by MicroRNA Mimics Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18079287 Requirements for T Lymphocyte Migration in Explanted Lymph Nodes Journal of Immunology (Baltimore, Md. : 1950). Jun, 2007 | Pubmed ID: 17548612 Positron Emission Tomography with Computed Tomography Imaging of Neuroinflammation in Experimental Autoimmune Encephalomyelitis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17261805 DNA-encoded Antibody Libraries: a Unified Platform for Multiplexed Cell Sorting and Detection of Genes and Proteins Journal of the American Chemical Society. Feb, 2007 | Pubmed ID: 17260987 Vascular Abnormalities in Mice Deficient for the G Protein-coupled Receptor GPR4 That Functions As a PH Sensor Molecular and Cellular Biology. Feb, 2007 | Pubmed ID: 17145776 Normal Immune Development and Glucocorticoid-induced Thymocyte Apoptosis in Mice Deficient for the T-cell Death-associated Gene 8 Receptor Molecular and Cellular Biology. Jan, 2006 | Pubmed ID: 16382156 Visualization of a Primary Anti-tumor Immune Response by Positron Emission Tomography Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16293690 Lysophosphatidylcholine-induced Surface Redistribution Regulates Signaling of the Murine G Protein-coupled Receptor G2A Molecular Biology of the Cell. May, 2005 | Pubmed ID: 15728718 Differential Proton Sensitivity of Related G Protein-coupled Receptors T Cell Death-associated Gene 8 and G2A Expressed in Immune Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15665078 Gi-independent Macrophage Chemotaxis to Lysophosphatidylcholine Via the Immunoregulatory GPCR G2A Blood. Feb, 2005 | Pubmed ID: 15383458 T Cell Chemotaxis to Lysophosphatidylcholine Through the G2A Receptor Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004 | Pubmed ID: 14681556 Using the BLT Humanized Mouse as a Stem Cell based Gene Therapy Tumor Model Dimitrios N. Vatakis1,2,3, Gregory C. Bristol1,2, Sohn G. Kim1,2, Bernard Levin1,2, Wei Liu4, Caius G. Radu4, Scott G. Kitchen1,2,3, Jerome A. Zack1,2,5 1Department of Medicine, Division of Hematology-Oncology, David Geffen School of Medicine at UCLA, 2UCLA AIDS Institute, 3Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, 4Department of Medical and Molecular Pharmacology, David Geffen School of Medicine at UCLA, 5Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at UCLA JoVE 4181 면역학 및 감염병학
Using the BLT Humanized Mouse as a Stem Cell based Gene Therapy Tumor Model Dimitrios N. Vatakis1,2,3, Gregory C. Bristol1,2, Sohn G. Kim1,2, Bernard Levin1,2, Wei Liu4, Caius G. Radu4, Scott G. Kitchen1,2,3, Jerome A. Zack1,2,5 1Department of Medicine, Division of Hematology-Oncology, David Geffen School of Medicine at UCLA, 2UCLA AIDS Institute, 3Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, 4Department of Medical and Molecular Pharmacology, David Geffen School of Medicine at UCLA, 5Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at UCLA JoVE 4181 면역학 및 감염병학