Charles D. Stiles Department of Cancer Biology Dana-Farber Cancer Institute Biography Publications Institution JoVE Articles Charles D. Stiles has not added a biography. If you are Charles D. Stiles and would like to personalize this page please email our Author Liaison for assistance. Publications Of Brains and Blood: Developmental Origins of Glioma Diversity? Cancer Cell. Oct, 2015 | Pubmed ID: 26461085 An Amino Terminal Phosphorylation Motif Regulates Intranuclear Compartmentalization of Olig2 in Neural Progenitor Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2014 | Pubmed ID: 24948806 Olig1 Function is Required to Repress Dlx1/2 and Interneuron Production in Mammalian Brain Neuron. Feb, 2014 | Pubmed ID: 24507192 New Progenitors NESTIN(g) in the EGL Nature Neuroscience. Dec, 2013 | Pubmed ID: 24270268 Molecular Imaging of Drug Transit Through the Blood-brain Barrier with MALDI Mass Spectrometry Imaging Scientific Reports. 2013 | Pubmed ID: 24091529 Genomic Analysis of Diffuse Pediatric Low-grade Gliomas Identifies Recurrent Oncogenic Truncating Rearrangements in the Transcription Factor MYBL1 Proceedings of the National Academy of Sciences of the United States of America. May, 2013 | Pubmed ID: 23633565 Separated at Birth? The Functional and Molecular Divergence of OLIG1 and OLIG2 Nature Reviews. Neuroscience. Dec, 2012 | Pubmed ID: 23165259 Asleep at the Switch: MEK Kinases Control Transit to Gliogenesis in Developing Cortex Neuron. Sep, 2012 | Pubmed ID: 22998861 Prospective, High-throughput Molecular Profiling of Human Gliomas Journal of Neuro-oncology. Jul, 2012 | Pubmed ID: 22821383 Identification of Molecular Compartments and Genetic Circuitry in the Developing Mammalian Kidney Development (Cambridge, England). May, 2012 | Pubmed ID: 22510988 Detection of KIAA1549-BRAF Fusion Transcripts in Formalin-fixed Paraffin-embedded Pediatric Low-grade Gliomas The Journal of Molecular Diagnostics : JMD. Nov, 2011 | Pubmed ID: 21884820 Report from the Fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop Neuro-oncology. Jul, 2011 | Pubmed ID: 21727208 The Central Nervous System-restricted Transcription Factor Olig2 Opposes P53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma Cancer Cell. Mar, 2011 | Pubmed ID: 21397859 Phosphorylation State of Olig2 Regulates Proliferation of Neural Progenitors Neuron. Mar, 2011 | Pubmed ID: 21382551 Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples PloS One. 2009 | Pubmed ID: 19924296 A Genome-wide Screen for Spatially Restricted Expression Patterns Identifies Transcription Factors That Regulate Glial Development The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2009 | Pubmed ID: 19741146 Phase II Study of Imatinib Mesylate for Recurrent Meningiomas (North American Brain Tumor Consortium Study 01-08) Neuro-oncology. Dec, 2009 | Pubmed ID: 19293394 Glioma Stem Cells: a Midterm Exam Neuron. Jun, 2008 | Pubmed ID: 18579075 Molecular Pathogenesis of Adult Brain Tumors and the Role of Stem Cells Neurologic Clinics. Nov, 2007 | Pubmed ID: 17964020 "Smad"eningly Erratic: Target Gene Methylation Determines Whether TGFbeta Promotes or Suppresses Malignant Glioma Developmental Cell. Mar, 2007 | Pubmed ID: 17336898 Olig2-regulated Lineage-restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma Neuron. Feb, 2007 | Pubmed ID: 17296553 The Bad Seed: PDGF Receptors Link Adult Neural Progenitors to Glioma Stem Cells Neuron. Jul, 2006 | Pubmed ID: 16846849 Development of NG2 Neural Progenitor Cells Requires Olig Gene Function Proceedings of the National Academy of Sciences of the United States of America. May, 2006 | Pubmed ID: 16682644 Evidence for Motoneuron Lineage-specific Regulation of Olig2 in the Vertebrate Neural Tube Developmental Biology. Apr, 2006 | Pubmed ID: 16469306 Targeted Molecular Therapy of Malignant Gliomas Current Oncology Reports. Jan, 2006 | Pubmed ID: 16464405 Novel Pheochromocytoma Susceptibility Loci Identified by Integrative Genomics Cancer Research. Nov, 2005 | Pubmed ID: 16266984 A HIF1alpha Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas PLoS Genetics. Jul, 2005 | Pubmed ID: 16103922 A Genome-wide in Situ Hybridization Map of RNA-binding Proteins Reveals Anatomically Restricted Expression in the Developing Mouse Brain BMC Developmental Biology. 2005 | Pubmed ID: 16033648 Targeted Molecular Therapy of Malignant Gliomas Current Neurology and Neuroscience Reports. May, 2005 | Pubmed ID: 15865884 Distinct Temporal Genetic Signatures of Neurogenic and Gliogenic Cues in Cortical Stem Cell Cultures Journal of Neurobiology. Jan, 2005 | Pubmed ID: 15389679 Mouse Brain Organization Revealed Through Direct Genome-scale TF Expression Analysis Science (New York, N.Y.). Dec, 2004 | Pubmed ID: 15618518 BHLH Transcription Factor Olig1 is Required to Repair Demyelinated Lesions in the CNS Science (New York, N.Y.). Dec, 2004 | Pubmed ID: 15604411 The Oligodendroglial Lineage Marker OLIG2 is Universally Expressed in Diffuse Gliomas Journal of Neuropathology and Experimental Neurology. May, 2004 | Pubmed ID: 15198128 Expression of the Guanine Nucleotide Exchange Factor, Mr-gef, is Regulated During the Differentiation of Specific Subsets of Telencephalic Neurons Brain Research. Developmental Brain Research. Dec, 2003 | Pubmed ID: 14643017 Lost in Space: Misregulated Positional Cues Create Tripotent Neural Progenitors in Cell Culture Neuron. Oct, 2003 | Pubmed ID: 14642266 Cross-repressive Interaction of the Olig2 and Nkx2.2 Transcription Factors in Developing Neural Tube Associated with Formation of a Specific Physical Complex The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003 | Pubmed ID: 14573534 Basic Helix-loop-helix Factors in Cortical Development Neuron. Jul, 2003 | Pubmed ID: 12848929 High-resolution Imaging Demonstrates Dynein-based Vesicular Transport of Activated Trk Receptors Journal of Neurobiology. Jun, 2002 | Pubmed ID: 12150505 Molecular Mechanisms Controlling Cortical Gliogenesis Current Opinion in Neurobiology. Jun, 2002 | Pubmed ID: 12049929 Common Developmental Requirement for Olig Function Indicates a Motor Neuron/oligodendrocyte Connection Cell. Apr, 2002 | Pubmed ID: 11955448 A Brain Tumor/Organotypic Slice Co-culture System for Studying Tumor Microenvironment and Targeted Drug Therapies Emily J. Chadwick1, David P. Yang1, Mariella G. Filbin2, Emanuele Mazzola3, Yu Sun1, Oded Behar1,4, Maria F. Pazyra-Murphy1, Liliana Goumnerova5, Keith L. Ligon6, Charles D. Stiles1, Rosalind A. Segal1 1Department of Cancer Biology, Dana-Farber Cancer Institute, 2Department of Pediatrics, Children's Hospital, 3Department of Biostatistics & Computational Biology, Dana-Farber Cancer Institute, 4Department of Developmental Biology and Cancer Research, Hebrew University of Jerusalem, 5Department of Neurosurgery, Children's Hospital, 6Center for Molecular Oncologic Pathology, Department of Medical Oncology, Dana-Farber Cancer Institute JoVE 53304 의학
A Brain Tumor/Organotypic Slice Co-culture System for Studying Tumor Microenvironment and Targeted Drug Therapies Emily J. Chadwick1, David P. Yang1, Mariella G. Filbin2, Emanuele Mazzola3, Yu Sun1, Oded Behar1,4, Maria F. Pazyra-Murphy1, Liliana Goumnerova5, Keith L. Ligon6, Charles D. Stiles1, Rosalind A. Segal1 1Department of Cancer Biology, Dana-Farber Cancer Institute, 2Department of Pediatrics, Children's Hospital, 3Department of Biostatistics & Computational Biology, Dana-Farber Cancer Institute, 4Department of Developmental Biology and Cancer Research, Hebrew University of Jerusalem, 5Department of Neurosurgery, Children's Hospital, 6Center for Molecular Oncologic Pathology, Department of Medical Oncology, Dana-Farber Cancer Institute JoVE 53304 의학