Chi-Huey Wong Genomics Research Center Academia Sinica Biography Publications Institution JoVE Articles Chi-Huey Wong has not added a biography. If you are Chi-Huey Wong and would like to personalize this page please email our Author Liaison for assistance. Publications 4(1H)-quinolone Derivatives Overcome Acquired Resistance to Anti-microtubule Agents by Targeting the Colchicine Site of β-tubulin European Journal of Medicinal Chemistry. Aug, 2019 | Pubmed ID: 31419740 Structure-guided Development of Purine Amide, Hydroxamate, and Amidoxime for the Inhibition of Non-small Cell Lung Cancer European Journal of Medicinal Chemistry. Jul, 2019 | Pubmed ID: 31376567 Targeting the Bacterial Transglycosylase: Antibiotic Development from a Structural Perspective ACS Infectious Diseases. Jul, 2019 | Pubmed ID: 31283163 An Efficient Modular One-Pot Synthesis of Heparin-Based Anticoagulant Idraparinux Journal of the American Chemical Society. Jul, 2019 | Pubmed ID: 31244187 Synthesis of Sialidase-Resistant Oligosaccharide and Antibody Glycoform Containing α2,6-Linked 3F-Neu5Ac Journal of the American Chemical Society. Apr, 2019 | Pubmed ID: 30969765 Signaling Pathway of Globo-series Glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in Breast Cancer Proceedings of the National Academy of Sciences of the United States of America. 02, 2019 | Pubmed ID: 30808745 Egg-based Influenza Split Virus Vaccine with Monoglycosylation Induces Cross-strain Protection Against Influenza Virus Infections Proceedings of the National Academy of Sciences of the United States of America. Feb, 2019 | Pubmed ID: 30782805 Oligosaccharide Synthesis and Translational Innovation Journal of the American Chemical Society. Mar, 2019 | Pubmed ID: 30716271 Development of a Universal Influenza Vaccine Using Hemagglutinin Stem Protein Produced from Pichia Pastoris Virology. 01, 2019 | Pubmed ID: 30388628 Synthesis of Modular Building Blocks Using Glycosyl Phosphate Donors for the Construction of Asymmetric N-Glycans Tetrahedron. Oct, 2018 | Pubmed ID: 30983640 Hierarchical and Programmable One-pot Synthesis of Oligosaccharides Nature Communications. 12, 2018 | Pubmed ID: 30523255 Programmable One-pot Synthesis of Heparin Pentasaccharides Enabling Access to Regiodefined Sulfate Derivatives Chemical Science. Aug, 2018 | Pubmed ID: 30310602 -GlcNAcylation Regulates the Stability and Enzymatic Activity of the Histone Methyltransferase EZH2 Proceedings of the National Academy of Sciences of the United States of America. 07, 2018 | Pubmed ID: 29941599 Towards New Antibiotics Targeting Bacterial Transglycosylase: Synthesis of a Lipid II Analog As Stable Transition-state Mimic Inhibitor Bioorganic & Medicinal Chemistry Letters. 09, 2018 | Pubmed ID: 29602680 Unprecedented Role of Hybrid N-Glycans As Ligands for HIV-1 Broadly Neutralizing Antibodies Journal of the American Chemical Society. 04, 2018 | Pubmed ID: 29578688 A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope Immunity. 03, 2018 | Pubmed ID: 29548671 Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase Journal of the American Chemical Society. 02, 2018 | Pubmed ID: 29411975 Free-electron-laser Coherent Diffraction Images of Individual Drug-carrying Liposome Particles in Solution Nanoscale. Jan, 2018 | Pubmed ID: 29362758 Glycoengineering of Antibody (Herceptin) Through Yeast Expression and in Vitro Enzymatic Glycosylation Proceedings of the National Academy of Sciences of the United States of America. Jan, 2018 | Pubmed ID: 29311294 The 2-anilino-4-amino-5-aroylthiazole-type Compound AS7128 Inhibits Lung Cancer Growth Through Decreased IASPP and P53 Interaction Cancer Science. Dec, 2017 | Pubmed ID: 29285847 An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3 Cell Chemical Biology. Dec, 2017 | Pubmed ID: 29033318 Glycans Function As Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development Immunity. Sep, 2017 | Pubmed ID: 28916265 Undecaprenyl Phosphate Phosphatase Activity of Undecaprenol Kinase Regulates the Lipid Pool in Gram-Positive Bacteria Biochemistry. 10, 2017 | Pubmed ID: 28872301 Residues Comprising the Enhanced Aromatic Sequon Influence Protein N-Glycosylation Efficiency Journal of the American Chemical Society. Sep, 2017 | Pubmed ID: 28820257 Substrate Preference and Interplay of Fucosyltransferase 8 and N-Acetylglucosaminyltransferases Journal of the American Chemical Society. Jul, 2017 | Pubmed ID: 28678517 Autoreactivity to Sulfatide by Human Invariant NKT Cells Journal of Immunology (Baltimore, Md. : 1950). 07, 2017 | Pubmed ID: 28526683 Crystal Structure of a Homogeneous IgG-Fc Glycoform with the N-Glycan Designed to Maximize the Antibody Dependent Cellular Cytotoxicity ACS Chemical Biology. May, 2017 | Pubmed ID: 28318221 An Effective Bacterial Fucosidase for Glycoprotein Remodeling ACS Chemical Biology. 01, 2017 | Pubmed ID: 28103685 A Cell-permeable and Triazole-forming Fluorescent Probe for Glycoconjugate Imaging in Live Cells Chemical Communications (Cambridge, England). Jan, 2017 | Pubmed ID: 28084480 Influenza A Surface Glycosylation and Vaccine Design Proceedings of the National Academy of Sciences of the United States of America. Jan, 2017 | Pubmed ID: 28028222 Preparation of Aluminum Oxide-Coated Glass Slides for Glycan Microarrays ACS Omega. Nov, 2016 | Pubmed ID: 30023491 Dengue Virus Infection Is Through a Cooperative Interaction Between a Mannose Receptor and CLEC5A on Macrophage As a Multivalent Hetero-Complex PloS One. 2016 | Pubmed ID: 27832191 Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human INKT Cell Activation ACS Chemical Biology. 12, 2016 | Pubmed ID: 27782396 Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death Through Interaction with Katanin Journal of Medicinal Chemistry. Sep, 2016 | Pubmed ID: 27536893 High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery Cell Chemical Biology. Jul, 2016 | Pubmed ID: 27447047 A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans Immunity. 07, 2016 | Pubmed ID: 27438765 The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate Journal of the American Chemical Society. Jun, 2016 | Pubmed ID: 27249581 Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch Immunity. 05, 2016 | Pubmed ID: 27192579 Exploring Human Glycosylation for Better Therapies Molecular Aspects of Medicine. 10, 2016 | Pubmed ID: 27178988 Peramivir Phosphonate Derivatives As Influenza Neuraminidase Inhibitors Journal of Medicinal Chemistry. 06, 2016 | Pubmed ID: 27167096 Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis Annual Review of Biochemistry. Jun, 2016 | Pubmed ID: 27145845 Glycolipid GD3 and GD3 Synthase Are Key Drivers for Glioblastoma Stem Cells and Tumorigenicity Proceedings of the National Academy of Sciences of the United States of America. May, 2016 | Pubmed ID: 27143722 Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G Cell. May, 2016 | Pubmed ID: 27114034 Modular Synthesis of N-glycans and Arrays for the Hetero-ligand Binding Analysis of HIV Antibodies Nature Chemistry. Apr, 2016 | Pubmed ID: 27001729 Stage-specific Embryonic Antigen-3 (SSEA-3) and β3GalT5 Are Cancer Specific and Significant Markers for Breast Cancer Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Jan, 2016 | Pubmed ID: 26677875 Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design Immunity. Nov, 2015 | Pubmed ID: 26588781 Latifolicinin A from a Fermented Soymilk Product and the Structure-Activity Relationship of Synthetic Analogues As Inhibitors of Breast Cancer Cell Growth Journal of Agricultural and Food Chemistry. Nov, 2015 | Pubmed ID: 26499209 Glycoprotein B7-H3 Overexpression and Aberrant Glycosylation in Oral Cancer and Immune Response Proceedings of the National Academy of Sciences of the United States of America. Oct, 2015 | Pubmed ID: 26438868 Colocalization of a CD1d-Binding Glycolipid with a Radiation-Attenuated Sporozoite Vaccine in Lymph Node-Resident Dendritic Cells for a Robust Adjuvant Effect Journal of Immunology (Baltimore, Md. : 1950). Sep, 2015 | Pubmed ID: 26254338 A Common Glycan Structure on Immunoglobulin G for Enhancement of Effector Functions Proceedings of the National Academy of Sciences of the United States of America. Aug, 2015 | Pubmed ID: 26253764 Chemistry in Taiwan and Academia Sinica Angewandte Chemie (International Ed. in English). Nov, 2015 | Pubmed ID: 26174003 Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity The Journal of Biological Chemistry. Aug, 2015 | Pubmed ID: 26170455 Effect of Sialylation on EGFR Phosphorylation and Resistance to Tyrosine Kinase Inhibition Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015 | Pubmed ID: 25971727 Glycopeptide Mimetics Recapitulate High-mannose-type Oligosaccharide Binding and Function Angewandte Chemie (International Ed. in English). May, 2015 | Pubmed ID: 25776945 Development of Globo-H Cancer Vaccine Accounts of Chemical Research. Mar, 2015 | Pubmed ID: 25665650 Oseltamivir Hydroxamate and Acyl Sulfonamide Derivatives As Influenza Neuraminidase Inhibitors Bioorganic & Medicinal Chemistry. Dec, 2014 | Pubmed ID: 25456388 Immunogenicity Study of Globo H Analogues with Modification at the Reducing or Nonreducing End of the Tumor Antigen Journal of the American Chemical Society. Dec, 2014 | Pubmed ID: 25371992 Sequence-constructive SELEX: a New Strategy for Screening DNA Aptamer Binding to Globo H Biochemical and Biophysical Research Communications. Sep, 2014 | Pubmed ID: 25159850 Enzymatic Synthesis of Lipid II and Analogues Angewandte Chemie (International Ed. in English). Jul, 2014 | Pubmed ID: 24990652 An Azido-BODIPY Probe for Glycosylation: Initiation of Strong Fluorescence Upon Triazole Formation Journal of the American Chemical Society. Jul, 2014 | Pubmed ID: 24955871 Tamiphosphor Monoesters As Effective Anti-influenza Agents European Journal of Medicinal Chemistry. Jun, 2014 | Pubmed ID: 24836064 Potent Adjuvant Effects of Novel NKT Stimulatory Glycolipids on Hemagglutinin Based DNA Vaccine for H5N1 Influenza Virus Antiviral Research. Jul, 2014 | Pubmed ID: 24786174 Development of Bacterial Transglycosylase Inhibitors As New Antibiotics: Moenomycin A Treatment for Drug-resistant Helicobacter Pylori Bioorganic & Medicinal Chemistry Letters. Jun, 2014 | Pubmed ID: 24775303 Broadly Neutralizing HIV Antibodies Define a Glycan-dependent Epitope on the Prefusion Conformation of Gp41 on Cleaved Envelope Trimers Immunity. May, 2014 | Pubmed ID: 24768347 The Multifaceted Effects of Polysaccharides Isolated from Dendrobium Huoshanense on Immune Functions with the Induction of Interleukin-1 Receptor Antagonist (IL-1ra) in Monocytes PloS One. 2014 | Pubmed ID: 24705413 Characterization of the Sialic Acid Binding Activity of Influenza A Viruses Using Soluble Variants of the H7 and H9 Hemagglutinins PloS One. 2014 | Pubmed ID: 24586849 Stage-specific Embryonic Antigen-4 As a Potential Therapeutic Target in Glioblastoma Multiforme and Other Cancers Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24550271 Chemical Constituents of Plectranthus Amboinicus and the Synthetic Analogs Possessing Anti-inflammatory Activity Bioorganic & Medicinal Chemistry. Mar, 2014 | Pubmed ID: 24491635 O-GlcNAcylation Regulates EZH2 Protein Stability and Function Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24474760 Vaccination of Monoglycosylated Hemagglutinin Induces Cross-strain Protection Against Influenza Virus Infections Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24469815 The Surface Carbohydrates of the Echinococcus Granulosus Larva Interact Selectively with the Rodent Kupffer Cell Receptor Molecular and Biochemical Parasitology. Nov-Dec, 2013 | Pubmed ID: 24361107 Lipoamide Channel-binding Sulfonamides Selectively Inhibit Mycobacterial Lipoamide Dehydrogenase Biochemistry. Dec, 2013 | Pubmed ID: 24251446 New Continuous Fluorometric Assay for Bacterial Transglycosylase Using Förster Resonance Energy Transfer Journal of the American Chemical Society. Nov, 2013 | Pubmed ID: 24131464 Effective Sugar Nucleotide Regeneration for the Large-scale Enzymatic Synthesis of Globo H and SSEA4 Journal of the American Chemical Society. Oct, 2013 | Pubmed ID: 24044869 Efficient Convergent Synthesis of Bi-, Tri-, and Tetra-antennary Complex Type N-glycans and Their HIV-1 Antigenicity Journal of the American Chemical Society. Oct, 2013 | Pubmed ID: 24032650 Immunization of Fucose-containing Polysaccharides from Reishi Mushroom Induces Antibodies to Tumor-associated Globo H-series Epitopes Proceedings of the National Academy of Sciences of the United States of America. Aug, 2013 | Pubmed ID: 23908400 Synthesis of Neisseria Meningitidis Serogroup W135 Capsular Oligosaccharides for Immunogenicity Comparison and Vaccine Development Angewandte Chemie (International Ed. in English). Aug, 2013 | Pubmed ID: 23843313 Synthesis and Vaccine Evaluation of the Tumor-associated Carbohydrate Antigen RM2 from Prostate Cancer Journal of the American Chemical Society. Jul, 2013 | Pubmed ID: 23819648 Different Immunity Elicited by Recombinant H5N1 Hemagglutinin Proteins Containing Pauci-mannose, High-mannose, or Complex Type N-glycans PloS One. 2013 | Pubmed ID: 23799128 B-cell Maturation Antigen is Modified by a Single N-glycan Chain That Modulates Ligand Binding and Surface Retention Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23776238 CLEC4F is an Inducible C-type Lectin in F4/80-positive Cells and is Involved in Alpha-galactosylceramide Presentation in Liver PloS One. 2013 | Pubmed ID: 23762286 Synthesis and Bioactivity of β-(1→4)-linked Oligomannoses and Partially Acetylated Derivatives The Journal of Organic Chemistry. Jul, 2013 | Pubmed ID: 23745711 The Immunologically Active Oligosaccharides Isolated from Wheatgrass Modulate Monocytes Via Toll-like Receptor-2 Signaling The Journal of Biological Chemistry. Jun, 2013 | Pubmed ID: 23629653 Cell-permeable Probe for Identification and Imaging of Sialidases Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23359711 Carbohydrate-based Vaccines with a Glycolipid Adjuvant for Breast Cancer Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23355685 Fucosyltransferase 8 As a Functional Regulator of Nonsmall Cell Lung Cancer Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013 | Pubmed ID: 23267084 Rapid Preparation of Mycobacterium N-glycolyl Lipid I and Lipid II Derivatives: a Biocatalytic Approach Chemistry (Weinheim an Der Bergstrasse, Germany). Jan, 2013 | Pubmed ID: 23229320 Chemical Probes for Drug-resistance Assessment by Binding Competition (RABC): Oseltamivir Susceptibility Evaluation Angewandte Chemie (International Ed. in English). Jan, 2013 | Pubmed ID: 23150231 6-alkynyl Fucose is a Bioorthogonal Analog for O-fucosylation of Epidermal Growth Factor-like Repeats and Thrombospondin Type-1 Repeats by Protein O-fucosyltransferases 1 and 2 Glycobiology. Feb, 2013 | Pubmed ID: 23045360 Development of Oseltamivir Phosphonate Congeners As Anti-influenza Agents Journal of Medicinal Chemistry. Oct, 2012 | Pubmed ID: 23009169 Effect of the Peptide Moiety of Lipid II on Bacterial Transglycosylase Angewandte Chemie (International Ed. in English). Oct, 2012 | Pubmed ID: 22952114 α-Glycosylation by D-glucosamine-derived Donors: Synthesis of Heparosan and Heparin Analogues That Interact with Mycobacterial Heparin-binding Hemagglutinin Journal of the American Chemical Society. May, 2012 | Pubmed ID: 22587381 Crystal Structure of Staphylococcus Aureus Transglycosylase in Complex with a Lipid II Analog and Elucidation of Peptidoglycan Synthesis Mechanism Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22493270 Acyl and Silyl Group Effects in Reactivity-based One-pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc4 and IV(2)Fuc-Lc4 Journal of the American Chemical Society. Mar, 2012 | Pubmed ID: 22390569 Engineering Transaldolase in Pichia Stipitis to Improve Bioethanol Production ACS Chemical Biology. Mar, 2012 | Pubmed ID: 22148723 Infection of Differentiated Porcine Airway Epithelial Cells by Influenza Virus: Differential Susceptibility to Infection by Porcine and Avian Viruses PloS One. 2011 | Pubmed ID: 22174804 Toward Automated Oligosaccharide Synthesis Angewandte Chemie (International Ed. in English). Dec, 2011 | Pubmed ID: 22127846 Avidity of CD1d-ligand-receptor Ternary Complex Contributes to T-helper 1 (Th1) Polarization and Anticancer Efficacy Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21987790 Efficient and Stereoselective Synthesis of α(2→9) Oligosialic Acids: from Monomers to Dodecamers Angewandte Chemie (International Ed. in English). Sep, 2011 | Pubmed ID: 21948436 A Practical Synthesis of Zanamivir Phosphonate Congeners with Potent Anti-influenza Activity Journal of the American Chemical Society. Nov, 2011 | Pubmed ID: 21942552 E339...R416 Salt Bridge of Nucleoprotein As a Feasible Target for Influenza Virus Inhibitors Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21930946 Total Synthesis of Polyprenyl N-glycolyl Lipid II As a Mycobacterial Transglycosylase Substrate Organic Letters. Oct, 2011 | Pubmed ID: 21913698 Hemagglutinin-neuraminidase Balance Confers Respiratory-droplet Transmissibility of the Pandemic H1N1 Influenza Virus in Ferrets Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21825167 Sialylation and Fucosylation of Epidermal Growth Factor Receptor Suppress Its Dimerization and Activation in Lung Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21709263 Vaccine Design of Hemagglutinin Glycoprotein Against Influenza Trends in Biotechnology. Sep, 2011 | Pubmed ID: 21640418 Chemistry and Glycobiology Chemical Communications (Cambridge, England). Jun, 2011 | Pubmed ID: 21503322 Broadly Neutralizing DNA Vaccine with Specific Mutation Alters the Antigenicity and Sugar-binding Activities of Influenza Hemagglutinin Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21321237 Effects of Neighboring Glycans on Antibody-carbohydrate Interaction Angewandte Chemie (International Ed. in English). Feb, 2011 | Pubmed ID: 21308915 Programmable One-pot Glycosylation Topics in Current Chemistry. 2011 | Pubmed ID: 21290217 Modulation of Substrate Specificities of D-sialic Acid Aldolase Through Single Mutations of Val-251 The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21270125 Ganoderma Lucidum Polysaccharides Induce Macrophage-Like Differentiation in Human Leukemia THP-1 Cells Via Caspase and P53 Activation Evidence-based Complementary and Alternative Medicine : ECAM. 2011 | Pubmed ID: 19696196 Combinatorial Alanine Substitution Enables Rapid Optimization of Cytochrome P450BM3 for Selective Hydroxylation of Large Substrates Chembiochem : a European Journal of Chemical Biology. Dec, 2010 | Pubmed ID: 21108271 High-throughput Identification of Antibacterials Against Methicillin-resistant Staphylococcus Aureus (MRSA) and the Transglycosylase Bioorganic & Medicinal Chemistry. Dec, 2010 | Pubmed ID: 21075637 Effect of Reishi Polysaccharides on Human Stem/progenitor Cells Bioorganic & Medicinal Chemistry. Dec, 2010 | Pubmed ID: 21055951 High-throughput Identification of Compounds Targeting Influenza RNA-dependent RNA Polymerase Activity Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 20974907 Differential Receptor Binding Affinities of Influenza Hemagglutinins on Glycan Arrays Journal of the American Chemical Society. Oct, 2010 | Pubmed ID: 20882975 Glycan Array on Aluminum Oxide-coated Glass Slides Through Phosphonate Chemistry Journal of the American Chemical Society. Sep, 2010 | Pubmed ID: 20822102 Regioselective Synthesis of Di-C-glycosylflavones Possessing Anti-inflammation Activities Organic & Biomolecular Chemistry. Oct, 2010 | Pubmed ID: 20725659 In Vivo Protection Provided by a Synthetic New Alpha-galactosyl Ceramide Analog Against Bacterial and Viral Infections in Murine Models Antimicrobial Agents and Chemotherapy. Oct, 2010 | Pubmed ID: 20660669 Combinatorial Approach Toward Synthesis of Small Molecule Libraries As Bacterial Transglycosylase Inhibitors Organic & Biomolecular Chemistry. Jun, 2010 | Pubmed ID: 20485795 Development of Trifunctional Probes for Glycoproteomic Analysis Chemical Communications (Cambridge, England). Aug, 2010 | Pubmed ID: 20467665 Highly Alpha-selective Sialyl Phosphate Donors for Efficient Preparation of Natural Sialosides Chemistry (Weinheim an Der Bergstrasse, Germany). Feb, 2010 | Pubmed ID: 20066711 6,8-Di-C-glycosyl Flavonoids from Dendrobium Huoshanense Journal of Natural Products. Feb, 2010 | Pubmed ID: 20055483 Profiling Carbohydrate-receptor Interaction with Recombinant Innate Immunity Receptor-Fc Fusion Proteins The Journal of Biological Chemistry. Dec, 2009 | Pubmed ID: 19837675 The Lifespan-promoting Effect of Acetic Acid and Reishi Polysaccharide Bioorganic & Medicinal Chemistry. Nov, 2009 | Pubmed ID: 19837596 Glycans on Influenza Hemagglutinin Affect Receptor Binding and Immune Response Proceedings of the National Academy of Sciences of the United States of America. Oct, 2009 | Pubmed ID: 19822741 Chemoenzymatic Elaboration of Monosaccharides Using Engineered Cytochrome P450BM3 Demethylases Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19805336 Iron Oxide/gold Core/shell Nanoparticles for Ultrasensitive Detection of Carbohydrate-protein Interactions Analytical Chemistry. Sep, 2009 | Pubmed ID: 19689135 New Development of Glycan Arrays Organic & Biomolecular Chemistry. Jun, 2009 | Pubmed ID: 19462030 Crystal Structure of the Membrane-bound Bifunctional Transglycosylase PBP1b from Escherichia Coli Proceedings of the National Academy of Sciences of the United States of America. Jun, 2009 | Pubmed ID: 19458048 HA-pseudotyped Retroviral Vectors for Influenza Antagonist Screening Journal of Biomolecular Screening. Mar, 2009 | Pubmed ID: 19211776 The Core Trisaccharide of an N-linked Glycoprotein Intrinsically Accelerates Folding and Enhances Stability Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19204290 A Consensus-hemagglutinin-based DNA Vaccine That Protects Mice Against Divergent H5N1 Influenza Viruses Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008 | Pubmed ID: 18765801 Quantitative Microarray Analysis of Intact Glycolipid-CD1d Interaction and Correlation with Cell-based Cytokine Production Journal of the American Chemical Society. Sep, 2008 | Pubmed ID: 18712867 Lectin-like Domain of Thrombomodulin Binds to Its Specific Ligand Lewis Y Antigen and Neutralizes Lipopolysaccharide-induced Inflammatory Response Blood. Nov, 2008 | Pubmed ID: 18711002 Sugar-assisted Glycopeptide Ligation with Complex Oligosaccharides: Scope and Limitations Journal of the American Chemical Society. Sep, 2008 | Pubmed ID: 18698778 Glycan Microarray of Globo H and Related Structures for Quantitative Analysis of Breast Cancer Proceedings of the National Academy of Sciences of the United States of America. Aug, 2008 | Pubmed ID: 18689688 Expression of Globo H and SSEA3 in Breast Cancer Stem Cells and the Involvement of Fucosyl Transferases 1 and 2 in Globo H Synthesis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2008 | Pubmed ID: 18685093 Glycan Arrays on Aluminum-coated Glass Slides Chemistry, an Asian Journal. Sep, 2008 | Pubmed ID: 18683161 A Concise and Flexible Synthesis of the Potent Anti-influenza Agents Tamiflu and Tamiphosphor Angewandte Chemie (International Ed. in English). 2008 | Pubmed ID: 18613158 Structure and Bioactivity of the Polysaccharides in Medicinal Plant Dendrobium Huoshanense Bioorganic & Medicinal Chemistry. Jun, 2008 | Pubmed ID: 18467102 In Vitro Evaluation of Neuraminidase Inhibitors Using the Neuraminidase-dependent Release Assay of Hemagglutinin-pseudotyped Viruses Antiviral Research. Sep, 2008 | Pubmed ID: 18453004 Design, Synthesis, and Evaluation of Trifluoromethyl Ketones As Inhibitors of SARS-CoV 3CL Protease Bioorganic & Medicinal Chemistry. Apr, 2008 | Pubmed ID: 18329272 Targeting the Carbohydrates on HIV-1: Interaction of Oligomannose Dendrons with Human Monoclonal Antibody 2G12 and DC-SIGN Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18310320 Domain Requirement of Moenomycin Binding to Bifunctional Transglycosylases and Development of High-throughput Discovery of Antibiotics Proceedings of the National Academy of Sciences of the United States of America. Jan, 2008 | Pubmed ID: 18182485 Glycolipids As Immunostimulating Agents Bioorganic & Medicinal Chemistry. Feb, 2008 | Pubmed ID: 18006319 Ganoderma Lucidum Polysaccharides in Human Monocytic Leukemia Cells: from Gene Expression to Network Construction BMC Genomics. Nov, 2007 | Pubmed ID: 17996095 Synthesis of Tamiflu and Its Phosphonate Congeners Possessing Potent Anti-influenza Activity Journal of the American Chemical Society. Oct, 2007 | Pubmed ID: 17850083 Structure-based Design and Synthesis of Highly Potent SARS-CoV 3CL Protease Inhibitors Chembiochem : a European Journal of Chemical Biology. Sep, 2007 | Pubmed ID: 17722121 Potent Immune-modulating and Anticancer Effects of NKT Cell Stimulatory Glycolipids Proceedings of the National Academy of Sciences of the United States of America. Jun, 2007 | Pubmed ID: 17566107 Sugar-assisted Ligation in Glycoprotein Synthesis Journal of the American Chemical Society. Jun, 2007 | Pubmed ID: 17523644 Tailored Glycoproteomics and Glycan Site Mapping Using Saccharide-selective Bioorthogonal Probes Journal of the American Chemical Society. Jun, 2007 | Pubmed ID: 17506567 Alkynyl Sugar Analogs for the Labeling and Visualization of Glycoconjugates in Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17296930 Glycoproteomic Probes for Fluorescent Imaging of Fucosylated Glycans in Vivo Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16895981 Screening for HIV Protease Inhibitors by Protection Against Activity-mediated Cytotoxicity in Escherichia Coli Journal of Virological Methods. Oct, 2006 | Pubmed ID: 16849028 Reishi Polysaccharides Induce Immunoglobulin Production Through the TLR4/TLR2-mediated Induction of Transcription Factor Blimp-1 The Journal of Biological Chemistry. Aug, 2006 | Pubmed ID: 16798741 Multi-enzyme One-pot Strategy for the Synthesis of Sialyl Lewis X-containing PSGL-1 Glycopeptide Carbohydrate Research. Sep, 2006 | Pubmed ID: 16762328 Stable Benzotriazole Esters As Mechanism-based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease Chemistry & Biology. Mar, 2006 | Pubmed ID: 16638531 The Antioxidant Protein Alkylhydroperoxide Reductase of Helicobacter Pylori Switches from a Peroxide Reductase to a Molecular Chaperone Function Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16481626 Novel Five-membered Iminocyclitol Derivatives As Selective and Potent Glycosidase Inhibitors: New Structures for Antivirals and Osteoarthritis Chembiochem : a European Journal of Chemical Biology. Jan, 2006 | Pubmed ID: 16397876 Protein Microarray Using Alpha-amino Acids As Metal Tags on Chips Bioorganic & Medicinal Chemistry Letters. Mar, 2005 | Pubmed ID: 15713398 Plasma Proteome of Severe Acute Respiratory Syndrome Analyzed by Two-dimensional Gel Electrophoresis and Mass Spectrometry Proceedings of the National Academy of Sciences of the United States of America. Dec, 2004 | Pubmed ID: 15572443 Polysaccharides of Ganoderma Lucidum Alter Cell Immunophenotypic Expression and Enhance CD56+ NK-cell Cytotoxicity in Cord Blood Bioorganic & Medicinal Chemistry. Nov, 2004 | Pubmed ID: 15465338 Studies on the Immuno-modulating and Anti-tumor Activities of Ganoderma Lucidum (Reishi) Polysaccharides Bioorganic & Medicinal Chemistry. Nov, 2004 | Pubmed ID: 15465337 Discovery of Picomolar Slow Tight-binding Inhibitors of Alpha-fucosidase Chemistry & Biology. Sep, 2004 | Pubmed ID: 15380190 Small Molecules Targeting Severe Acute Respiratory Syndrome Human Coronavirus Proceedings of the National Academy of Sciences of the United States of America. Jul, 2004 | Pubmed ID: 15226499 Regioselective Glycosylation of Neamine Core: a Facile Entry to Kanamycin B Related Analogues Organic Letters. Feb, 2004 | Pubmed ID: 14961629 Rapid Diversity-oriented Synthesis in Microtiter Plates for in Situ Screening: Discovery of Potent and Selective Alpha-fucosidase Inhibitors Angewandte Chemie (International Ed. in English). Oct, 2003 | Pubmed ID: 14533157 Studies on the Immuno-modulating and Antitumor Activities of Ganoderma Lucidum (Reishi) Polysaccharides: Functional and Proteomic Analyses of a Fucose-containing Glycoprotein Fraction Responsible for the Activities Bioorganic & Medicinal Chemistry. Apr, 2002 | Pubmed ID: 11836115 The Thioglycoside and Glycosyl Phosphite of 5-Azido Sialic Acid: Excellent Donors for the α-Glycosylation of Primary Hydroxy Groups Angewandte Chemie (International Ed. in English). Aug, 2001 | Pubmed ID: 29711986 The Thioglycoside and Glycosyl Phosphite of 5-Azido Sialic Acid: Excellent Donors for the Alpha-Glycosylation of Primary Hydroxy Groups This Research Was Supported by Academia Sinica (Taipei) and the NIH (USA) Angewandte Chemie (International Ed. in English). Aug, 2001 | Pubmed ID: 11500903 Hierarkisk og programmerbar en-pot oligosaccharid syntese Cheng-Wei Cheng1, Yixuan Zhou1, Wen-Harn Pan2, Supriya Dey3, Chung-Yi Wu1, Wen-Lian Hsu4, Chi-Huey Wong1,3 1Genomics Research Center, Academia Sinica, 2Institute of Biomedical Sciences, Academia Sinica, 3Department of Chemistry, Scripps Research Institute, 4Institute of Information Science, Academia Sinica JoVE 59987 화학 Kemo-enzymatisk syntese af N- glycans for arrayet udvikling og HIV antistof profilering Sachin S. Shivatare1, Vidya S. Shivatare1, Chung-Yi Wu1, Chi-Huey Wong1 1Genomics Research Center, Academia Sinica JoVE 55855 화학
Hierarkisk og programmerbar en-pot oligosaccharid syntese Cheng-Wei Cheng1, Yixuan Zhou1, Wen-Harn Pan2, Supriya Dey3, Chung-Yi Wu1, Wen-Lian Hsu4, Chi-Huey Wong1,3 1Genomics Research Center, Academia Sinica, 2Institute of Biomedical Sciences, Academia Sinica, 3Department of Chemistry, Scripps Research Institute, 4Institute of Information Science, Academia Sinica JoVE 59987 화학
Kemo-enzymatisk syntese af N- glycans for arrayet udvikling og HIV antistof profilering Sachin S. Shivatare1, Vidya S. Shivatare1, Chung-Yi Wu1, Chi-Huey Wong1 1Genomics Research Center, Academia Sinica JoVE 55855 화학