Christian Vanhove Department of Electronics and Information Systems / Institute Biomedical Engineering and Technology Ghent University Biography Publications Institution JoVE Articles Christian Vanhove Christian Vanhove graduated as a Biomedical Engineer from Brussels University in 1990. From 1991-2011, he worked as medical physicist expert in nuclear medicine with research focussing on all aspects of medical image processing and analysis. He obtained a PhD in Medical Sciences in 2004 at Brussels University. In 2005, he was one of the initiators of the laboratory animal imaging facility of Brussels University, where he worked as a postdoctoral researcher. During this period his research was focused on imaging quantification in laboratory animal imaging. Since 2011, he joined the Institute of Biomedical Engineering and Technology of the Faculty of Engineering and Architecture of Ghent University, where he is director of the laboratory animal imaging facility. Christian Vanhove is associate professor and lecturer in biomedical engineering. Publications Non-viral Delivery of Chemically Modified MRNA to the Retina: Subretinal Versus Intravitreal Administration Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2019 | Pubmed ID: 31265881 PET Quantification of [18F]MPPF in the Canine Brain Using Blood Input and Reference Tissue Modelling PloS One. Month, 2019 | Pubmed ID: 31185062 Technical Feasibility of [F]FET and [F]FAZA PET Guided Radiotherapy in a F98 Glioblastoma Rat Model Radiation Oncology (London, England). May, 2019 | Pubmed ID: 31146757 In Vivo Measurement of Hepatic Drug Transporter Inhibition with Radiolabeled Bile Acids Methods in Molecular Biology (Clifton, N.J.). Month, 2019 | Pubmed ID: 31016649 A 3D CFD Model of the Interstitial Fluid Pressure and Drug Distribution in Heterogeneous Tumor Nodules During Intraperitoneal Chemotherapy Drug Delivery. Dec, 2019 | Pubmed ID: 30929523 Near-infrared Fluorescence Guided Esophageal Reconstructive Surgery: A Systematic Review World Journal of Gastrointestinal Oncology. Mar, 2019 | Pubmed ID: 30918597 New Fluoroethyl Phenylalanine Analogues As Potential LAT1-targeting PET Tracers for Glioblastoma Scientific Reports. Feb, 2019 | Pubmed ID: 30814660 The Path Toward PET-Guided Radiation Therapy for Glioblastoma in Laboratory Animals: A Mini Review Frontiers in Medicine. Month, 2019 | Pubmed ID: 30761302 Dynamic Changes in Hippocampal Diffusion and Kurtosis Metrics Following Experimental MTBI Correlate with Glial Reactivity NeuroImage. Clinical. Month, 2019 | Pubmed ID: 30658945 Plant-PET to Investigate Phloem Vulnerability to Drought in Populus Tremula Under Changing Climate Regimes Tree Physiology. 02, 2019 | Pubmed ID: 30597097 Validation of Hepatobiliary Transport PET Imaging in Liver Function Assessment: Evaluation of 3β-[F]FCA in Mouse Models of Liver Disease Nuclear Medicine and Biology. Jan - Feb, 2019 | Pubmed ID: 30595544 Magnetic Resonance Imaging-guided Radiation Therapy Using Animal Models of Glioblastoma The British Journal of Radiology. Mar, 2019 | Pubmed ID: 30563357 Angiopoietin-2 Promotes Pathological Angiogenesis and Is a Therapeutic Target in Murine Nonalcoholic Fatty Liver Disease Hepatology (Baltimore, Md.). Mar, 2019 | Pubmed ID: 30259536 Species-dependent Extracranial Manifestations of a Brain Seeking Breast Cancer Cell Line PloS One. Month, 2018 | Pubmed ID: 30532191 Performance Evaluation of the LightPath Imaging System for Intra-operative Cerenkov Luminescence Imaging Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB). Aug, 2018 | Pubmed ID: 30139600 Regional Alterations of Cerebral [F]FDG Metabolism in the Chronic Unpredictable Mild Stress- and the Repeated Corticosterone Depression Model in Rats Journal of Neural Transmission (Vienna, Austria : 1996). Sep, 2018 | Pubmed ID: 29955973 Evaluating Hepatobiliary Transport with F-Labeled Bile Acids: The Effect of Radiolabel Position and Bile Acid Structure on Radiosynthesis and and Performance Contrast Media & Molecular Imaging. Month, 2018 | Pubmed ID: 29853807 Hypoxia Imaging with F-FAZA PET/CT Predicts Radiotherapy Response in Esophageal Adenocarcinoma Xenografts Radiation Oncology (London, England). Mar, 2018 | Pubmed ID: 29514673 Heterocellular 3D Scaffolds As Biomimetic to Recapitulate the Tumor Microenvironment of Peritoneal Metastases In vitro and In vivo Biomaterials. 03, 2018 | Pubmed ID: 29306747 ESTRO ACROP: Technology for Precision Small Animal Radiotherapy Research: Optimal Use and Challenges Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Mar, 2018 | Pubmed ID: 29269093 Adipose-Derived Mesenchymal Stromal Cells Improve the Healing of Colonic Anastomoses Following High Dose of Irradiation Through Anti-Inflammatory and Angiogenic Processes Cell Transplantation. 12, 2017 | Pubmed ID: 29390877 Radiotherapy-activated Cancer-associated Fibroblasts Promote Tumor Progression Through Paracrine IGF-1R Activation Cancer Research. Dec, 2017 | Pubmed ID: 29217764 TNFR1 Inhibition with a Nanobody Protects Against EAE Development in Mice Scientific Reports. Oct, 2017 | Pubmed ID: 29057962 Co-delivery of Nucleoside-modified MRNA and TLR Agonists for Cancer Immunotherapy: Restoring the Immunogenicity of Immunosilent MRNA Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2017 | Pubmed ID: 28987878 Toward Smart Design of Retinal Drug Carriers: a Novel Bovine Retinal Explant Model to Study the Barrier Role of the Vitreoretinal Interface Drug Delivery. Nov, 2017 | Pubmed ID: 28925755 Improved Xenograft Efficiency of Esophageal Adenocarcinoma Cell Lines Through in Vivo Selection Oncology Reports. Jul, 2017 | Pubmed ID: 28504813 In Vivo DCE-MRI for the Discrimination Between Glioblastoma and Radiation Necrosis in Rats Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Dec, 2017 | Pubmed ID: 28303489 Synthesis, in Vitro and in Vivo Evaluation of 3β-[18F]fluorocholic Acid for the Detection of Drug-induced Cholestasis in Mice PloS One. Month, 2017 | Pubmed ID: 28273180 Mathematical Modeling of Intraperitoneal Drug Delivery: Simulation of Drug Distribution in a Single Tumor Nodule Drug Delivery. Nov, 2017 | Pubmed ID: 28181817 The VEGFR Inhibitor Cediranib Improves the Efficacy of Fractionated Radiotherapy in a Colorectal Cancer Xenograft Model European Surgical Research. Europaische Chirurgische Forschung. Recherches Chirurgicales Europeennes. Month, 2017 | Pubmed ID: 28002822 18F-FCho PET and MRI for the Prediction of Response in Glioblastoma Patients According to the RANO Criteria Nuclear Medicine Communications. Mar, 2017 | Pubmed ID: 27984537 Haematopoietic Prolyl Hydroxylase-1 Deficiency Promotes M2 Macrophage Polarization and is Both Necessary and Sufficient to Protect Against Experimental Colitis The Journal of Pathology. Mar, 2017 | Pubmed ID: 27981571 Functional Circuit Mapping of Striatal Output Nuclei Using Simultaneous Deep Brain Stimulation and FMRI NeuroImage. Feb, 2017 | Pubmed ID: 27825979 Kinetic Modeling and Graphical Analysis of 18F-Fluoromethylcholine (FCho), 18F-Fluoroethyltyrosine (FET) and 18F-Fluorodeoxyglucose (FDG) PET for the Fiscrimination Between High-Grade Glioma and Radiation Necrosis in Rats PloS One. Month, 2016 | Pubmed ID: 27559736 Synthesis, in Vitro and in Vivo Small-animal SPECT Evaluation of Novel Technetium Labeled Bile Acid Analogues to Study (altered) Hepatic Transporter Function Nuclear Medicine and Biology. Oct, 2016 | Pubmed ID: 27513813 Repetitive Transcranial Magnetic Stimulation for the Treatment of Refractory Epilepsy Expert Review of Neurotherapeutics. Sep, 2016 | Pubmed ID: 27254399 Sortase A-mediated Site-specific Labeling of Camelid Single-domain Antibody-fragments: a Versatile Strategy for Multiple Molecular Imaging Modalities Contrast Media & Molecular Imaging. Sep, 2016 | Pubmed ID: 27147480 Quantitative and Functional Requirements for Bioluminescent Cancer Models In Vivo (Athens, Greece). Jan-Feb, 2016 | Pubmed ID: 26709122 Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2016 | Pubmed ID: 26449837 Vulnerable Plaque Detection and Quantification with Gold Particle-Enhanced Computed Tomography in Atherosclerotic Mouse Models Molecular Imaging. May, 2015 | Pubmed ID: 28654406 MRI-Only Based Radiotherapy Treatment Planning for the Rat Brain on a Small Animal Radiation Research Platform (SARRP) PloS One. Month, 2015 | Pubmed ID: 26633302 Accurate Molecular Imaging of Small Animals Taking into Account Animal Models, Handling, Anaesthesia, Quality Control and Imaging System Performance EJNMMI Physics. Dec, 2015 | Pubmed ID: 26560138 Collimator Design for a Multipinhole Brain SPECT Insert for MRI Medical Physics. Nov, 2015 | Pubmed ID: 26520758 Radiation-induced Lung Damage Promotes Breast Cancer Lung-metastasis Through CXCR4 Signaling Oncotarget. Sep, 2015 | Pubmed ID: 26396176 Pretreatment with VEGF(R)-inhibitors Reduces Interstitial Fluid Pressure, Increases Intraperitoneal Chemotherapy Drug Penetration, and Impedes Tumor Growth in a Mouse Colorectal Carcinomatosis Model Oncotarget. Oct, 2015 | Pubmed ID: 26375674 Review of SPECT Collimator Selection, Optimization, and Fabrication for Clinical and Preclinical Imaging Medical Physics. Aug, 2015 | Pubmed ID: 26233207 Functional MRI During Hippocampal Deep Brain Stimulation in the Healthy Rat Brain PloS One. Month, 2015 | Pubmed ID: 26193653 Tumor-environment Biomimetics Delay Peritoneal Metastasis Formation by Deceiving and Redirecting Disseminated Cancer Cells Biomaterials. Jun, 2015 | Pubmed ID: 25907048 Hippocampal Deep Brain Stimulation Reduces Glucose Utilization in the Healthy Rat Brain Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Jun, 2015 | Pubmed ID: 25361593 (18)F-fluoromethylcholine (FCho), (18)F-fluoroethyltyrosine (FET), and (18)F-fluorodeoxyglucose (FDG) for the Discrimination Between High-grade Glioma and Radiation Necrosis in Rats: a PET Study Nuclear Medicine and Biology. Jan, 2015 | Pubmed ID: 25218024 Fate of Xylem-transported 11C- and 13C-labeled CO2 in Leaves of Poplar Physiologia Plantarum. Apr, 2015 | Pubmed ID: 25142926 Use of a Ray-Based Reconstruction Algorithm to Accurately Quantify Preclinical MicroSPECT Images Molecular Imaging. Jun, 2014 | Pubmed ID: 28650292 Cancer-associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling Cancer Research. Dec, 2014 | Pubmed ID: 25252914 MRI-guided 3D Conformal Arc Micro-irradiation of a F98 Glioblastoma Rat Model Using the Small Animal Radiation Research Platform (SARRP) Journal of Neuro-oncology. Nov, 2014 | Pubmed ID: 25069566 Role of Metallothioneins As Danger Signals in the Pathogenesis of Colitis The Journal of Pathology. May, 2014 | Pubmed ID: 24452846 Temperature Dependence of APD-based PET Scanners Medical Physics. Sep, 2013 | Pubmed ID: 24007182 In Vivo Visualization and Quantification of (Disturbed) Oatp-mediated Hepatic Uptake and Mrp2-mediated Biliary Excretion of 99mTc-mebrofenin in Mice Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Apr, 2013 | Pubmed ID: 23440558 In vivo Disassembly of IV Administered SiRNA Matrix Nanoparticles at the Renal Filtration Barrier Biomaterials. Mar, 2013 | Pubmed ID: 23261216 Magnetic Resonace-based Attenuation Correction for Micro-single-photon Emission Computed Tomography Molecular Imaging. Apr, 2012 | Pubmed ID: 22469243 Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform Sam Donche1, Jeroen Verhoeven1, Benedicte Descamps2, Charlotte Bouckaert3, Robrecht Raedt3, Christian Vanhove2, Ingeborg Goethals1 1Department of Diagnostic Sciences, Ghent University, 2Department of Electronics and Information Systems, Ghent University, 3Department of Head and Skin, Ghent University JoVE 62560 암 연구학 Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury Kim Braeckman1, Benedicte Descamps1, Christian Vanhove1 1Infinity lab, Medical Imaging and Signal Processing Group, Ghent University JoVE 60012 신경과학 PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator Julie Bolcaen1, Benedicte Descamps2, Tom Boterberg3, Christian Vanhove2, Ingeborg Goethals1 1Department of Nuclear Medicine, Ghent University Hospital, 2IBiTech-MEDISIP, Department of Electronics and Information Systems, Ghent University, 3Department of Radiation Oncology, Ghent University Hospital JoVE 56601 암 연구학
Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform Sam Donche1, Jeroen Verhoeven1, Benedicte Descamps2, Charlotte Bouckaert3, Robrecht Raedt3, Christian Vanhove2, Ingeborg Goethals1 1Department of Diagnostic Sciences, Ghent University, 2Department of Electronics and Information Systems, Ghent University, 3Department of Head and Skin, Ghent University JoVE 62560 암 연구학
Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury Kim Braeckman1, Benedicte Descamps1, Christian Vanhove1 1Infinity lab, Medical Imaging and Signal Processing Group, Ghent University JoVE 60012 신경과학
PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator Julie Bolcaen1, Benedicte Descamps2, Tom Boterberg3, Christian Vanhove2, Ingeborg Goethals1 1Department of Nuclear Medicine, Ghent University Hospital, 2IBiTech-MEDISIP, Department of Electronics and Information Systems, Ghent University, 3Department of Radiation Oncology, Ghent University Hospital JoVE 56601 암 연구학