Christopher J.H. Porter Drug Delivery, Disposition, and Dynamics, Monash Institute of Pharmaceutical Sciences Monash University (Parkville Campus) Biography Publications Institution JoVE Articles Christopher J.H. Porter has not added a biography. If you are Christopher J.H. Porter and would like to personalize this page please email our Author Liaison for assistance. Publications PEGylation Does Not Significantly Change the Initial Intravenous or Subcutaneous Pharmacokinetics or Lymphatic Exposure of Trastuzumab in Rats but Increases Plasma Clearance After Subcutaneous Administration Molecular Pharmaceutics. Mar, 2015 | Pubmed ID: 25644368 Size and Rigidity of Cylindrical Polymer Brushes Dictate Long Circulating Properties in Vivo ACS Nano. Feb, 2015 | Pubmed ID: 25634484 Optimal PEGylation Can Improve the Exposure of Interferon in the Lungs Following Pulmonary Administration Journal of Pharmaceutical Sciences. Jan, 2015 | Pubmed ID: 25631360 Methotrexate-conjugated PEGylated Dendrimers Show Differential Patterns of Deposition and Activity in Tumour-burdened Lymph Nodes After Intravenous and Subcutaneous Administration in Rats Molecular Pharmaceutics. Dec, 2014 | Pubmed ID: 25485615 Profiling the Role of Deacylation-Reacylation in the Lymphatic Transport of a Triglyceride-Mimetic Prodrug Pharmaceutical Research. Dec, 2014 | Pubmed ID: 25446770 Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase Pharmaceutical Research. Oct, 2014 | Pubmed ID: 25288015 Toward the Establishment of Standardized in Vitro Tests for Lipid-based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels The AAPS Journal. Nov, 2014 | Pubmed ID: 25274609 An in Vitro Digestion Test That Reflects Rat Intestinal Conditions to Probe the Importance of Formulation Digestion Vs First Pass Metabolism in Danazol Bioavailability from Lipid Based Formulations Molecular Pharmaceutics. Nov, 2014 | Pubmed ID: 25265395 In Vitro-in Vivo Evaluation of Lipid Based Formulations of the CETP Inhibitors CP-529,414 (torcetrapib) and CP-532,623 European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V. Nov, 2014 | Pubmed ID: 25152213 Characterization of Two Distinct Modes of Drug Binding to Human Intestinal Fatty Acid Binding Protein ACS Chemical Biology. Nov, 2014 | Pubmed ID: 25144524 'Stealth' Lipid-based Formulations: Poly(ethylene Glycol)-mediated Digestion Inhibition Improves Oral Bioavailability of a Model Poorly Water Soluble Drug Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2014 | Pubmed ID: 25058571 Digestion of Phospholipids After Secretion of Bile into the Duodenum Changes the Phase Behavior of Bile Components Molecular Pharmaceutics. Aug, 2014 | Pubmed ID: 24987935 Toward the Establishment of Standardized in Vitro Tests for Lipid-based Formulations, Part 4: Proposing a New Lipid Formulation Performance Classification System Journal of Pharmaceutical Sciences. Aug, 2014 | Pubmed ID: 24985238 The Influence of Intestinal Lymphatic Transport on the Systemic Exposure and Brain Deposition of a Novel Highly Lipophilic Compound with Structural Similarity to Cholesterol The Journal of Pharmacy and Pharmacology. Oct, 2014 | Pubmed ID: 24821499 Nano-chemotherapeutics: Maximising Lymphatic Drug Exposure to Improve the Treatment of Lymph-metastatic Cancers Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2014 | Pubmed ID: 24801249 Lipid-based Formulations Solidified Via Adsorption Onto the Mesoporous Carrier Neusilin® US2: Effect of Drug Type and Formulation Composition on in Vitro Pharmaceutical Performance Journal of Pharmaceutical Sciences. Jun, 2014 | Pubmed ID: 24740767 Pulmonary Administration of a Doxorubicin-conjugated Dendrimer Enhances Drug Exposure to Lung Metastases and Improves Cancer Therapy Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2014 | Pubmed ID: 24637466 Pulmonary and Systemic Pharmacokinetics of Inhaled and Intravenous Colistin Methanesulfonate in Cystic Fibrosis Patients: Targeting Advantage of Inhalational Administration Antimicrobial Agents and Chemotherapy. May, 2014 | Pubmed ID: 24550334 Non-linear Increases in Danazol Exposure with Dose in Older Vs. Younger Beagle Dogs: the Potential Role of Differences in Bile Salt Concentration, Thermodynamic Activity, and Formulation Digestion Pharmaceutical Research. Jun, 2014 | Pubmed ID: 24477676 Choice of Nonionic Surfactant Used to Formulate Type IIIA Self-emulsifying Drug Delivery Systems and the Physicochemical Properties of the Drug Have a Pronounced Influence on the Degree of Drug Supersaturation That Develops During in Vitro Digestion Journal of Pharmaceutical Sciences. Apr, 2014 | Pubmed ID: 24470073 Targeted Delivery of a Model Immunomodulator to the Lymphatic System: Comparison of Alkyl Ester Versus Triglyceride Mimetic Lipid Prodrug Strategies Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2014 | Pubmed ID: 24398334 Ionic Liquids Provide Unique Opportunities for Oral Drug Delivery: Structure Optimization and in Vivo Evidence of Utility Chemical Communications (Cambridge, England). Feb, 2014 | Pubmed ID: 24394756 The Lymphatic System Plays a Major Role in the Intravenous and Subcutaneous Pharmacokinetics of Trastuzumab in Rats Molecular Pharmaceutics. Feb, 2014 | Pubmed ID: 24350780 Recent Advances in Lipid-based Formulation Technology Pharmaceutical Research. Dec, 2013 | Pubmed ID: 24158727 Gastric Pre-processing is an Important Determinant of the Ability of Medium-chain Lipid Solution Formulations to Enhance Oral Bioavailability in Rats Journal of Pharmaceutical Sciences. Nov, 2013 | Pubmed ID: 23983139 PEGylated Polylysine Dendrimers Increase Lymphatic Exposure to Doxorubicin when Compared to PEGylated Liposomal and Solution Formulations of Doxorubicin Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2013 | Pubmed ID: 23954628 Population Pharmacokinetics of Colistin Methanesulfonate in Rats: Achieving Sustained Lung Concentrations of Colistin for Targeting Respiratory Infections Antimicrobial Agents and Chemotherapy. Oct, 2013 | Pubmed ID: 23917323 Lipid-based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/absorption Pathway Pharmaceutical Research. Dec, 2013 | Pubmed ID: 23824582 Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles Pharmaceutical Research. Dec, 2013 | Pubmed ID: 23793990 Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients Pharmaceutical Research. Dec, 2013 | Pubmed ID: 23771564 Pulmonary Administration of PEGylated Polylysine Dendrimers: Absorption from the Lung Versus Retention Within the Lung is Highly Size-dependent Molecular Pharmaceutics. Aug, 2013 | Pubmed ID: 23750747 A Simple Quantitative Approach for the Determination of Long and Medium Chain Lipids in Bio-relevant Matrices by High Performance Liquid Chromatography with Refractive Index Detection AAPS PharmSciTech. Sep, 2013 | Pubmed ID: 23733513 The Potential for Drug Supersaturation During Intestinal Processing of Lipid-based Formulations May Be Enhanced for Basic Drugs Molecular Pharmaceutics. Jul, 2013 | Pubmed ID: 23697606 The Impact of Lymphatic Transport on the Systemic Disposition of Lipophilic Drugs Journal of Pharmaceutical Sciences. Jul, 2013 | Pubmed ID: 23696002 In Vitro Assessment of Drug-free and Fenofibrate-containing Lipid Formulations Using Dispersion and Digestion Testing Gives Detailed Insights into the Likely Fate of Formulations in the Intestine European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jul, 2013 | Pubmed ID: 23684915 Toward the Establishment of Standardized in Vitro Tests for Lipid-based Formulations, Part 3: Understanding Supersaturation Versus Precipitation Potential During the in Vitro Digestion of Type I, II, IIIA, IIIB and IV Lipid-based Formulations Pharmaceutical Research. Dec, 2013 | Pubmed ID: 23661145 Evaluation of the Structural Determinants of Polymeric Precipitation Inhibitors Using Solvent Shift Methods and Principle Component Analysis Molecular Pharmaceutics. Aug, 2013 | Pubmed ID: 23631696 PEGylation of Interferon α2 Improves Lymphatic Exposure After Subcutaneous and Intravenous Administration and Improves Antitumour Efficacy Against Lymphatic Breast Cancer Metastases Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2013 | Pubmed ID: 23499718 Intestinal Bile Secretion Promotes Drug Absorption from Lipid Colloidal Phases Via Induction of Supersaturation Molecular Pharmaceutics. May, 2013 | Pubmed ID: 23480483 A Mouse Model to Evaluate the Impact of Species, Sex, and Lipid Load on Lymphatic Drug Transport Pharmaceutical Research. Dec, 2013 | Pubmed ID: 23430484 Strategies to Address Low Drug Solubility in Discovery and Development Pharmacological Reviews. Jan, 2013 | Pubmed ID: 23383426 Silica-lipid Hybrid (SLH) Formulations Enhance the Oral Bioavailability and Efficacy of Celecoxib: An in Vivo Evaluation Journal of Controlled Release : Official Journal of the Controlled Release Society. Apr, 2013 | Pubmed ID: 23353808 The Effect of Administered Dose of Lipid-based Formulations on the in Vitro and in Vivo Performance of Cinnarizine As a Model Poorly Water-soluble Drug Journal of Pharmaceutical Sciences. Feb, 2013 | Pubmed ID: 23242691 In Vitro Digestion Testing of Lipid-based Delivery Systems: Calcium Ions Combine with Fatty Acids Liberated from Triglyceride Rich Lipid Solutions to Form Soaps and Reduce the Solubilization Capacity of Colloidal Digestion Products International Journal of Pharmaceutics. Jan, 2013 | Pubmed ID: 23178598 Toward the Establishment of Standardized in Vitro Tests for Lipid-based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations During in Vitro Digestion Molecular Pharmaceutics. Nov, 2012 | Pubmed ID: 23030411 Incomplete Desorption of Liquid Excipients Reduces the in Vitro and in Vivo Performance of Self-emulsifying Drug Delivery Systems Solidified by Adsorption Onto an Inorganic Mesoporous Carrier Molecular Pharmaceutics. Sep, 2012 | Pubmed ID: 22870936 Lipid Digestion As a Trigger for Supersaturation: Evaluation of the Impact of Supersaturation Stabilization on the in Vitro and in Vivo Performance of Self-emulsifying Drug Delivery Systems Molecular Pharmaceutics. Jul, 2012 | Pubmed ID: 22656917 Toward the Establishment of Standardized in Vitro Tests for Lipid-based Formulations, Part 1: Method Parameterization and Comparison of in Vitro Digestion Profiles Across a Range of Representative Formulations Journal of Pharmaceutical Sciences. Sep, 2012 | Pubmed ID: 22644939 Intravenous Dosing Conditions May Affect Systemic Clearance for Highly Lipophilic Drugs: Implications for Lymphatic Transport and Absolute Bioavailability Studies Journal of Pharmaceutical Sciences. Sep, 2012 | Pubmed ID: 22623170 化疗药物的树状 Nanocarriers 协会: 评估的共价键共轭非共价封装相比的优点。 Molecular Pharmaceutics. Jan, 2012 | Pubmed ID: 22250750 阿霉素共轭乙二醇树状显示但低毒性的乙二醇脂质体和解决方案制剂在小鼠和大鼠肿瘤模型相比类似抗肿瘤活性。 Molecular Pharmaceutics. Jan, 2012 | Pubmed ID: 22233281 阿霉素药代动力学、 抗肿瘤活性和毒性变化比较介导乙二醇树状物和乙二醇脂质体给药系统。 Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2012 | Pubmed ID: 21704192 修正"有针对性的药物传递到淋巴细胞: 路由到特定于站点的免疫调节?"。 Molecular Pharmaceutics. Dec, 2011 | Pubmed ID: 21995681 树状物药代动力学: 化合物对大小、 结构和表面特性的影响。 Nanomedicine (London, England). Aug, 2011 | Pubmed ID: 21955077 乙二醇纳米材料的胶体结构的差异决定加速的血液清关的可能性。 Journal of Pharmaceutical Sciences. Nov, 2011 | Pubmed ID: 21721002 针对使用树突状聚合物 (树形) 的淋巴管。 Advanced Drug Delivery Reviews. Sep, 2011 | Pubmed ID: 21683746 急性甘油三酯升高促进肠淋巴脂质和毒品运输: 脂质和药物吸收积极的反馈机制。 Molecular Pharmaceutics. Aug, 2011 | Pubmed ID: 21604764 脂肪酸结合蛋白: 在肠上皮中的游离药物运输的潜在伴侣吗? Pharmaceutical Research. Sep, 2011 | Pubmed ID: 21523511 纳米液体结晶颗粒口服后为不善水溶性药物提供长工期缓释作用。 Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2011 | Pubmed ID: 21497623 特性和肿瘤靶向的乙二醇聚赖氨酸树枝状轴承阿霉素通过 Ph 值不耐热链接器。 Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2011 | Pubmed ID: 21315119 Preparation, Crystallization and Preliminary X-ray Diffraction Analysis of Two Intestinal Fatty-acid Binding Proteins in the Presence of 11-(dansylamino)undecanoic Acid Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Feb, 2011 | Pubmed ID: 21301109 封顶甲氨蝶呤 α-羧基增强了系统性风险,并保留的药物共轭乙二醇聚赖氨酸树枝状细胞毒性。 Molecular Pharmaceutics. Apr, 2011 | Pubmed ID: 21171585 使用聚合物沉淀抑制剂提高差水溶性药物的吸收: 实用程序的机械基础。 Journal of Drug Targeting. Dec, 2010 | Pubmed ID: 20973755 有针对性的药物传递给淋巴细胞: 路由到特定于站点的免疫调节作用吗? Molecular Pharmaceutics. Dec, 2010 | Pubmed ID: 20958081 Phytantriol 和甘油单油酸酯立方液体结晶阶段作为缓释口服给药系统很差水溶性药物二。在体内评价。 The Journal of Pharmacy and Pharmacology. Jul, 2010 | Pubmed ID: 20636873 Phytantriol 和甘油单油酸酯立方液体结晶阶段作为缓释口服给药系统生理相关介质中水不溶性药物 I.相行为。 The Journal of Pharmacy and Pharmacology. Jul, 2010 | Pubmed ID: 20636872 淋巴访问的两个胆固醇酯转运蛋白抑制剂 (CP524,515 和 CP532,623) 的机制和评价其对淋巴脂蛋白谱的影响。 Pharmaceutical Research. Sep, 2010 | Pubmed ID: 20635194 小肠淋巴管吸收的两个高度亲脂性胆固醇酯转运蛋白抑制剂 (CP524,515 和 CP532,623) 的作用。 Pharmaceutical Research. May, 2010 | Pubmed ID: 20221896 后口服亩高度敏感到 Coadministered 脂质的大众 Methylnortestosterone 睾酮 (MU) 的淋巴运输和 Methylnortestosterone 生物利用度。 The Journal of Pharmacology and Experimental Therapeutics. Nov, 2009 | Pubmed ID: 19696095 探测贝特绑定大鼠肝脂肪酸结合蛋白的特异性。 Journal of Medicinal Chemistry. Sep, 2009 | Pubmed ID: 19663428 口服生物利用度评估和肠淋巴和运输的组织结构图 45697 Org 46035,类似物高度亲脂性新型免疫调节剂两种。 Current Drug Delivery. Aug, 2009 | Pubmed ID: 19534711 乙二醇的药代动力学及肿瘤的处置,甲氨蝶呤共轭树枝状聚-l-赖氨酸。 Molecular Pharmaceutics. Jul-Aug, 2009 | Pubmed ID: 19453158 肠淋巴运输增强了通过避免首次通过代谢的新型大麻受体激动剂对餐后口服生物利用度。 Pharmaceutical Research. Jun, 2009 | Pubmed ID: 19280324 亲脂性药物绑定到大鼠小肠脂肪酸结合蛋白的表征。 Molecular and Cellular Biochemistry. Jun, 2009 | Pubmed ID: 19160019 搅拌的水层和受体的相对作用评价接收器中限制体外肠道通透性的不同亲脂性药物化合物。 The Journal of Pharmacy and Pharmacology. Oct, 2008 | Pubmed ID: 18812024 大鼠肝脂肪酸结合蛋白药物结合特异性的表征。 Journal of Medicinal Chemistry. Jul, 2008 | Pubmed ID: 18533710 分子量和聚乙二醇的影响链系统性的药代动力学研究的乙二醇聚 L-赖氨酸树枝状的长度。 Molecular Pharmaceutics. May-Jun, 2008 | Pubmed ID: 18393438 基于脂质的增强交付制度难溶性药物。 Advanced Drug Delivery Reviews. Mar, 2008 | Pubmed ID: 18160174 加强肠道的药物 Solubilisation 使用基于脂质的运载系统。 Advanced Drug Delivery Reviews. Mar, 2008 | Pubmed ID: 18155801 基于脂质的运载工具和肠淋巴药物运输: 机械的更新。 Advanced Drug Delivery Reviews. Mar, 2008 | Pubmed ID: 18155316 口服基于脂质的运载系统的制订: 材料、 方法和战略。 Advanced Drug Delivery Reviews. Mar, 2008 | Pubmed ID: 18068260 表面活性剂丹那唑对狗的油脂乳化配方口服后生物利用度消化的影响的评价。 Journal of Pharmaceutical Sciences. Feb, 2008 | Pubmed ID: 18064698 血浆蛋白作为溶解剂在体外渗透性实验中的使用: 使用相互渗透的方法未绑定的药物浓度的校正。 Journal of Pharmaceutical Sciences. Jan, 2008 | Pubmed ID: 17585392 聚-L-赖氨酸树枝状与阴离子 Arylsulfonate 或琥珀酸团体静脉药代动力学和处置的表面衍生的影响。 Molecular Pharmaceutics. Nov-Dec, 2007 | Pubmed ID: 17953445 淋巴吸收的皮下管理蛋白质: 不同注射部位吸收 Darbepoetin 阿尔法使用羊模型的影响。 Drug Metabolism and Disposition: the Biological Fate of Chemicals. Dec, 2007 | Pubmed ID: 17875672 低剂量脂配方: 对胃排空和胆汁分泌的影响。 Pharmaceutical Research. Nov, 2007 | Pubmed ID: 17657595 一个基于脂质的液体的结晶矩阵提供持续释放和增强对大鼠模型水不溶性药物口服生物利用度。 International Journal of Pharmaceutics. Aug, 2007 | Pubmed ID: 17467935 审查的作用小肠脂肪酸结合蛋白在药物吸收并行人工膜渗透法检测中。 Chemistry & Biology. Apr, 2007 | Pubmed ID: 17462580 与血脂的乳化脂质基础配方丹那唑提高表面活性剂 (Cremophor EL) 的比例含量减少了在小猎兔犬口服生物利用度。 Pharmaceutical Research. Apr, 2007 | Pubmed ID: 17372700 血脂及脂质基础配方: 优化的亲脂性药物的口服给药。 Nature Reviews. Drug Discovery. Mar, 2007 | Pubmed ID: 17330072 Cremophor EL 和吐 80 对大鼠空肠跨地高辛通透性的影响: 划定的热力学和转运蛋白相关事件使用相互渗透的方法。 Journal of Pharmaceutical Sciences. Feb, 2007 | Pubmed ID: 17051595 阳离子多聚-L-赖氨酸树枝状: 药代动力学、 体内分布和代谢和 Bioresorption 对大鼠静脉给药后的证据。 Molecular Pharmaceutics. Sep-Oct, 2006 | Pubmed ID: 17009860 Darbepoetin 阿尔法 · 罗密欧的吸收发生主要通过皮下注射后到羊的淋巴管。 Pharmaceutical Research. Sep, 2006 | Pubmed ID: 16951999 差水溶性化合物溶条件下渗透率评估: 相互渗透的办法。 Journal of Pharmaceutical Sciences. Oct, 2006 | Pubmed ID: 16883557 在基于血脂的药物制剂对大鼠的肠道输液期间发生急性和重合增加 FABP 表达及淋巴脂质和毒品运输。 Pharmaceutical Research. Aug, 2006 | Pubmed ID: 16858652 考试范围的 Pluronic 表面活性剂对它产生抗药性的脂类制剂体外 Solubilisation 行为和口腔生物的影响。 The Journal of Pharmacy and Pharmacology. Jun, 2006 | Pubmed ID: 16734982 在大鼠基于肠上皮的代谢与淋巴药物运输之间的相互作用的一种考试。 Drug Metabolism and Disposition: the Biological Fate of Chemicals. May, 2006 | Pubmed ID: 16467133 淋巴脂质前体池是肠淋巴药物运输的一个关键决定因素。 The Journal of Pharmacology and Experimental Therapeutics. Feb, 2006 | Pubmed ID: 16249368 滴滴涕的组织吸收的乳糜微粒代谢无关。 Archives of Toxicology. Apr, 2006 | Pubmed ID: 16180009 Subcutaneous Drug Delivery and the Role of the Lymphatics Drug Discovery Today. Technologies. 2005 | Pubmed ID: 24981760 胆增加禁食大鼠小肠淋巴药物运输。 Pharmaceutical Research. Nov, 2005 | Pubmed ID: 16132351 从大肠杆菌大鼠肝型脂肪酸结合蛋白的分离纯化方法的改进。 Protein Expression and Purification. Nov, 2005 | Pubmed ID: 15914028 亲脂性药物与小肠脂肪酸结合蛋白的相互作用。 The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15722357 对低水溶性药物的吸收共同制定血脂的中间消化阶段的影响。 Journal of Pharmaceutical Sciences. Mar, 2005 | Pubmed ID: 15619248 淋巴吸收是 Epoetin 阿尔法 · 罗密欧的系统可用性的主要捐助者对羊后皮下注射。 The Journal of Pharmacology and Experimental Therapeutics. Apr, 2005 | Pubmed ID: 15579493 新型立方的阶段中链脂来源为交付差水溶性药物。 Journal of Controlled Release : Official Journal of the Controlled Release Society. Sep, 2004 | Pubmed ID: 15380632 作为中链脂微乳配方脂酶消化易感性后管理减少了达那唑的口服生物利用度。 Pharmaceutical Research. Aug, 2004 | Pubmed ID: 15359575 利用体外脂质消化数据解释体内的甘油三酯基于口头脂质制剂溶性药物性能: 卤泛群与研究。 Journal of Pharmaceutical Sciences. May, 2004 | Pubmed ID: 15067688 药物溶解悬浮制剂的甘油三酯血脂低水溶性药物的体外消化期间的行为。 Pharmaceutical Research. Feb, 2004 | Pubmed ID: 15032306 期间体外消化的简单的甘油三酯脂溶液配方的药物增溶行为。 Pharmaceutical Research. Feb, 2004 | Pubmed ID: 15032305 与血浆脂蛋白关系的一系列的脂肪族酯的卤泛群模式对理化性质的影响。 Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2004 | Pubmed ID: 14980776 卤泛群对约束条件的改变脂蛋白的影响评价致 QTc 间隔延长麻醉的家兔模型中。 The Journal of Pharmacy and Pharmacology. Jan, 2004 | Pubmed ID: 14980003 重组人白血病抑制因子在羊中的药代动力学。 The Journal of Pharmacology and Experimental Therapeutics. Jun, 2004 | Pubmed ID: 14872093 后管理基于脂质的运载系统的探测在胃肠道的药物增溶模式: 阶段图办法。 Journal of Pharmaceutical Sciences. Feb, 2004 | Pubmed ID: 14705191 在口服给药的剂量单位基于脂质的配方的禁食狗后发生肠淋巴运输的卤泛群。 Pharmaceutical Research. Sep, 2003 | Pubmed ID: 14567642 考试的口服吸收和淋巴管运输的卤泛群犬三空心后自微乳给药系统 (自微乳化) 包含在管理结构甘油三酯。 European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Sep, 2003 | Pubmed ID: 13678797 药代动力学模型来描述 R-metHu-瘦素皮下注射到羊的淋巴管吸收。 Pharmaceutical Research. Aug, 2003 | Pubmed ID: 12948012 考试的体外肠道通透性数据室建模中的应用: 评估组织吸收、 P-糖蛋白和 CYP3A 的影响。 Drug Metabolism and Disposition: the Biological Fate of Chemicals. Sep, 2003 | Pubmed ID: 12920171 Lymphatically 运输的睾酮睾酮的全身暴露意识到淋巴导管空心犬两个安特尔配方口服后作出贡献。 The Journal of Pharmacology and Experimental Therapeutics. Sep, 2003 | Pubmed ID: 12807999 使用分区方法的聚合物探针热力学溶性药物增溶在模型脂质消化产品的活动。 Journal of Pharmaceutical Sciences. Jun, 2003 | Pubmed ID: 12761815 立体淋巴管吸收不会有助于对映体的卤泛群在体内的药代动力学吗? Biopharmaceutics & Drug Disposition. May, 2003 | Pubmed ID: 12698498 吸收、 外排和维拉帕米在 Autoperfused 大鼠空肠代谢动力学评价。 The Journal of Pharmacology and Experimental Therapeutics. Apr, 2003 | Pubmed ID: 12649363 Desbutylhalofantrine: Qt 间期延长和其他心血管的影响后评价体内静脉给药。 Journal of Cardiovascular Pharmacology. Mar, 2003 | Pubmed ID: 12605019 分离和表征的胶体阶段制作关于共同制订脂肪的消化和明显的选定差水溶性药物溶解度对其影响的评估。 Journal of Pharmaceutical Sciences. Mar, 2003 | Pubmed ID: 12587125 聚乙二醇 400、 Pluronic P85 和维他命 E D-α-生育酚聚乙二醇 1000年丁二酸对 P-糖蛋白外排和离体的大鼠小肠基于肠上皮的代谢的影响的一种体外检查。 AAPS PharmSci. 2002 | Pubmed ID: 12646011 结构化的卤泛群口服给药的甘油三酯车辆: 清醒大鼠小肠淋巴运输和生物利用度的考试。 Pharmaceutical Research. Sep, 2002 | Pubmed ID: 12403073 理化基础广泛肠淋巴运输的不善脂质可溶性抗疟药、 盐酸卤泛群,给狗餐后口服。 Journal of Pharmaceutical Sciences. Mar, 2002 | Pubmed ID: 11920750 长期和中期链甘油酯的体外消化配置文件和它们的脂肪产品的相行为的评价。 The Journal of Pharmacy and Pharmacology. Jan, 2002 | Pubmed ID: 11833493 在肠系膜淋巴管空心大鼠模型:应用肠淋巴药物运输的评估 Natalie L. Trevaskis1, Luojuan Hu1, Suzanne M. Caliph1, Sifei Han1, Christopher J.H. Porter1 1Drug Delivery, Disposition, and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus) 면역학 및 감염병학
在肠系膜淋巴管空心大鼠模型:应用肠淋巴药物运输的评估 Natalie L. Trevaskis1, Luojuan Hu1, Suzanne M. Caliph1, Sifei Han1, Christopher J.H. Porter1 1Drug Delivery, Disposition, and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus) 면역학 및 감염병학