Christopher L. Mendias Department of Orthopaedic Surgery University of Michigan Medical School Biography Publications Institution JoVE Articles Christopher L. Mendias has not added a biography. If you are Christopher L. Mendias and would like to personalize this page please email our Author Liaison for assistance. Publications Ex Situ Limb Perfusion System to Extend Vascularized Composite Tissue Allograft Survival in Swine Transplantation. Apr, 2015 | Pubmed ID: 25929606 Haploinsufficiency of Myostatin Protects Against Aging-related Declines in Muscle Function and Enhances the Longevity of Mice Aging Cell. Mar, 2015 | Pubmed ID: 25808276 P38 MAPK Signaling in Postnatal Tendon Growth and Remodeling PloS One. 2015 | Pubmed ID: 25768932 Mouse Forepaw Lumbrical Muscles Are Resistant to Age-related Declines in Force Production Experimental Gerontology. May, 2015 | Pubmed ID: 25762422 Changes in Skeletal Muscle and Tendon Structure and Function Following Genetic Inactivation of Myostatin in Rats The Journal of Physiology. Apr, 2015 | Pubmed ID: 25640143 TGF-β Superfamily Signaling in Muscle and Tendon Adaptation to Resistance Exercise Exercise and Sport Sciences Reviews. Apr, 2015 | Pubmed ID: 25607281 Inducible Depletion of Satellite Cells in Adult, Sedentary Mice Impairs Muscle Regenerative Capacity Without Affecting Sarcopenia Nature Medicine. Jan, 2015 | Pubmed ID: 25501907 Simvastatin Reduces Fibrosis and Protects Against Muscle Weakness After Massive Rotator Cuff Tear Journal of Shoulder and Elbow Surgery / American Shoulder and Elbow Surgeons ... [et Al.]. Feb, 2015 | Pubmed ID: 25213828 Reduced Muscle Fiber Force Production and Disrupted Myofibril Architecture in Patients with Chronic Rotator Cuff Tears Journal of Shoulder and Elbow Surgery / American Shoulder and Elbow Surgeons ... [et Al.]. Jan, 2015 | Pubmed ID: 25193488 Muscle Fibers Are Injured at the Time of Acute and Chronic Rotator Cuff Repair Clinical Orthopaedics and Related Research. Jan, 2015 | Pubmed ID: 25113269 Synergist Ablation Induces Rapid Tendon Growth Through the Synthesis of a Neotendon Matrix Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2014 | Pubmed ID: 25277742 Inhibition of 5-LOX, COX-1, and COX-2 Increases Tendon Healing and Reduces Muscle Fibrosis and Lipid Accumulation After Rotator Cuff Repair The American Journal of Sports Medicine. Dec, 2014 | Pubmed ID: 25245131 Intrinsic Stiffness of Extracellular Matrix Increases with Age in Skeletal Muscles of Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2014 | Pubmed ID: 24994884 Changes in Macrophage Phenotype and Induction of Epithelial-to-mesenchymal Transition Genes Following Acute Achilles Tenotomy and Repair Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Jul, 2014 | Pubmed ID: 24700411 Elevation in Circulating Biomarkers of Cartilage Damage and Inflammation in Athletes with Femoroacetabular Impingement The American Journal of Sports Medicine. Nov, 2013 | Pubmed ID: 23959964 Aging-associated Exacerbation in Fatty Degeneration and Infiltration After Rotator Cuff Tear Journal of Shoulder and Elbow Surgery / American Shoulder and Elbow Surgeons ... [et Al.]. Jun, 2013 | Pubmed ID: 23790676 Targeted Inhibition of TGF-β Results in an Initial Improvement but Long Term Deficit in Force Production After Contraction-induced Skeletal Muscle Injury Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2013 | Pubmed ID: 23766498 Changes in Circulating Biomarkers of Muscle Atrophy, Inflammation, and Cartilage Turnover in Patients Undergoing Anterior Cruciate Ligament Reconstruction and Rehabilitation The American Journal of Sports Medicine. Aug, 2013 | Pubmed ID: 23739685 MMP Inhibition As a Potential Method to Augment the Healing of Skeletal Muscle and Tendon Extracellular Matrix Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2013 | Pubmed ID: 23640595 Atrogin-1, MuRF-1, and Sarcopenia Endocrine. Feb, 2013 | Pubmed ID: 22815045 TGF-β1 Enhances Contractility in Engineered Skeletal Muscle Journal of Tissue Engineering and Regenerative Medicine. Jul, 2013 | Pubmed ID: 22371337 Hyaluronic Acid, HAS1, and HAS2 Are Significantly Upregulated During Muscle Hypertrophy American Journal of Physiology. Cell Physiology. Sep, 2012 | Pubmed ID: 22785117 Rotator Cuff Tear Reduces Muscle Fiber Specific Force Production and Induces Macrophage Accumulation and Autophagy Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Dec, 2012 | Pubmed ID: 22696414 Mechanical Loading and TGF-β Change the Expression of Multiple MiRNAs in Tendon Fibroblasts Journal of Applied Physiology (Bethesda, Md. : 1985). Jul, 2012 | Pubmed ID: 22539168 Transforming Growth Factor-beta Induces Skeletal Muscle Atrophy and Fibrosis Through the Induction of Atrogin-1 and Scleraxis Muscle & Nerve. Jan, 2012 | Pubmed ID: 22190307 Physiological Loading of Tendons Induces Scleraxis Expression in Epitenon Fibroblasts Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Apr, 2012 | Pubmed ID: 21913219 Decreased Specific Force and Power Production of Muscle Fibers from Myostatin-deficient Mice Are Associated with a Suppression of Protein Degradation Journal of Applied Physiology (Bethesda, Md. : 1985). Jul, 2011 | Pubmed ID: 21565991 The Aging of Elite Male Athletes: Age-related Changes in Performance and Skeletal Muscle Structure and Function Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine. Nov, 2008 | Pubmed ID: 19001883 Tendons of Myostatin-deficient Mice Are Small, Brittle, and Hypocellular Proceedings of the National Academy of Sciences of the United States of America. Jan, 2008 | Pubmed ID: 18162552 Contractile Properties of EDL and Soleus Muscles of Myostatin-deficient Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2006 | Pubmed ID: 16709649 Role of Cyclooxygenase-1 and -2 in Satellite Cell Proliferation, Differentiation, and Fusion Muscle & Nerve. Oct, 2004 | Pubmed ID: 15372441 Measurement of Maximum Isometric Force Generated by Permeabilized Skeletal Muscle Fibers Stuart M. Roche1, Jonathan P. Gumucio1,2, Susan V. Brooks2,3, Christopher L. Mendias1,2, Dennis R. Claflin3,4 1Department of Orthopaedic Surgery, University of Michigan Medical School, 2Department of Molecular & Integrative Physiology, University of Michigan Medical School, 3Department of Biomedical Engineering, University of Michigan Medical School, 4Department of Surgery, Section of Plastic Surgery, University of Michigan Medical School JoVE 52695 생체공학
Measurement of Maximum Isometric Force Generated by Permeabilized Skeletal Muscle Fibers Stuart M. Roche1, Jonathan P. Gumucio1,2, Susan V. Brooks2,3, Christopher L. Mendias1,2, Dennis R. Claflin3,4 1Department of Orthopaedic Surgery, University of Michigan Medical School, 2Department of Molecular & Integrative Physiology, University of Michigan Medical School, 3Department of Biomedical Engineering, University of Michigan Medical School, 4Department of Surgery, Section of Plastic Surgery, University of Michigan Medical School JoVE 52695 생체공학