Daniel Irimia BioMEMS Resource Center, Department of Surgery Massachusetts General Hospital–Harvard Medical School–Shriners Burns Hospital Biography Publications Institution JoVE Articles Daniel Irimia has not added a biography. If you are Daniel Irimia and would like to personalize this page please email our Author Liaison for assistance. Publications Technical Advance: Changes in Neutrophil Migration Patterns Upon Contact with Platelets in a Microfluidic Assay Journal of Leukocyte Biology. Mar, 2017 | Pubmed ID: 27630219 Microfluidic Platform to Evaluate Migration of Cells from Patients with DYT1 Dystonia Journal of Neuroscience Methods. May, 2014 | Pubmed ID: 24880044 A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration As an Anti-inflammatory Mechanism Science Translational Medicine. Feb, 2014 | Pubmed ID: 24574340 Cell Migration in Confined Environments Methods in Cell Biology. 2014 | Pubmed ID: 24560508 Migration of Neutrophils Targeting Amyloid Plaques in Alzheimer's Disease Mouse Model Neurobiology of Aging. Jun, 2014 | Pubmed ID: 24485508 On-demand, Competing Gradient Arrays for Neutrophil Chemotaxis Lab on a Chip. Mar, 2014 | Pubmed ID: 24430002 Retrotaxis of Human Neutrophils During Mechanical Confinement Inside Microfluidic Channels Integrative Biology : Quantitative Biosciences from Nano to Macro. Feb, 2014 | Pubmed ID: 24419464 Measuring Neutrophil Speed and Directionality During Chemotaxis, Directly from a Droplet of Whole Blood Technology. Oct, 2013 | Pubmed ID: 24809064 Biased Migration of Confined Neutrophil-like Cells in Asymmetric Hydraulic Environments Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013 | Pubmed ID: 24324148 Malaria-infected Erythrocyte-derived Microvesicles Mediate Cellular Communication Within the Parasite Population and with the Host Immune System Cell Host & Microbe. May, 2013 | Pubmed ID: 23684304 Microfluidic Chemotaxis Platform for Differentiating the Roles of Soluble and Bound Amyloid-β on Microglial Accumulation Scientific Reports. 2013 | Pubmed ID: 23665843 Mitochondrial Localization and the Persistent Migration of Epithelial Cancer Cells Biophysical Journal. May, 2013 | Pubmed ID: 23663851 Resolvin D2 Restores Neutrophil Directionality and Improves Survival After Burns FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2013 | Pubmed ID: 23430978 Resolvin D2 Prevents Secondary Thrombosis and Necrosis in a Mouse Burn Wound Model Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Jan-Feb, 2013 | Pubmed ID: 23110665 MICROFLUIDIC DEVICE FOR EXAMINING DIRECTIONAL SENSING IN DENDRITIC CELL CHEMOTAXIS Nano LIFE. Jun, 2012 | Pubmed ID: 24073020 Microfluidic Chambers for Monitoring Leukocyte Trafficking and Humanized Nano-proresolving Medicines Interactions Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23185003 Critical Role for Lysyl Oxidase in Mesenchymal Stem Cell-driven Breast Cancer Malignancy Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012 | Pubmed ID: 23033492 A Portable Chemotaxis Platform for Short and Long Term Analysis PloS One. 2012 | Pubmed ID: 23028729 Multiple Phenotypes in Huntington Disease Mouse Neural Stem Cells Molecular and Cellular Neurosciences. May, 2012 | Pubmed ID: 22508027 Resolvin E2 Formation and Impact in Inflammation Resolution Journal of Immunology (Baltimore, Md. : 1950). May, 2012 | Pubmed ID: 22450811 Epithelial Cell Guidance by Self-generated EGF Gradients Integrative Biology : Quantitative Biosciences from Nano to Macro. Feb, 2012 | Pubmed ID: 22314635 Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility Science (New York, N.Y.). Jan, 2012 | Pubmed ID: 22174129 Photoelectron Photoion Coincidence Imaging of Ultrafast Control in Multichannel Molecular Dynamics Faraday Discussions. 2011 | Pubmed ID: 22452081 On a Chip IEEE Pulse. Nov, 2011 | Pubmed ID: 22147065 Controlled Loading of Cryoprotectants (CPAs) to Oocyte with Linear and Complex CPA Profiles on a Microfluidic Platform Lab on a Chip. Oct, 2011 | Pubmed ID: 21887438 Decoding Functional Metabolomics with Docosahexaenoyl Ethanolamide (DHEA) Identifies Novel Bioactive Signals The Journal of Biological Chemistry. Sep, 2011 | Pubmed ID: 21757729 The Reaction Microscope: Imaging and Pulse Shaping Control in Photodynamics Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. May, 2011 | Pubmed ID: 21557438 Subsets of Human CD4(+) Regulatory T Cells Express the Peripheral Homing Receptor CXCR3 European Journal of Immunology. Aug, 2011 | Pubmed ID: 21538345 The Reaction Microscope: Imaging and Pulse Shaping Control in Photodynamics Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Jun, 2011 | Pubmed ID: 21506237 Microfluidics for T- Lymphocyte Cell Separation and Inflammation Monitoring in Burn Patients Clinical and Translational Science. Feb, 2011 | Pubmed ID: 21348958 Ultrasensitive Detection of Low-abundance Surface-marker Protein Using Isothermal Rolling Circle Amplification in a Microfluidic Nanoliter Platform Small (Weinheim an Der Bergstrasse, Germany). Feb, 2011 | Pubmed ID: 21294269 Microfluidic Proportional Flow Controller Journal of Micromechanics and Microengineering : Structures, Devices, and Systems. Oct, 2010 | Pubmed ID: 21874096 A Genome-wide RNAi Screen Identifies Multiple RSK-dependent Regulators of Cell Migration Genes & Development. Dec, 2010 | Pubmed ID: 21062900 Isolation of Circulating Tumor Cells Using a Microvortex-generating Herringbone-chip Proceedings of the National Academy of Sciences of the United States of America. Oct, 2010 | Pubmed ID: 20930119 Clinical Microfluidics for Neutrophil Genomics and Proteomics Nature Medicine. Sep, 2010 | Pubmed ID: 20802500 Burn Injury Reduces Neutrophil Directional Migration Speed in Microfluidic Devices PloS One. 2010 | Pubmed ID: 20689600 Directional Decisions During Neutrophil Chemotaxis Inside Bifurcating Channels Integrative Biology : Quantitative Biosciences from Nano to Macro. Nov, 2010 | Pubmed ID: 20676444 Controlled Induction of Distributed Microdeformation in Wounded Tissue Via a Microchamber Array Dressing Journal of Biomedical Materials Research. Part A. Nov, 2010 | Pubmed ID: 20607869 Toward Elucidating the Mechanism of Femtosecond Pulse Shaping Control in Photodynamics of Molecules by Velocity Map Photoelectron and Ion Imaging The Journal of Chemical Physics. Jun, 2010 | Pubmed ID: 20572700 Microfluidic Technologies for Temporal Perturbations of Chemotaxis Annual Review of Biomedical Engineering. Aug, 2010 | Pubmed ID: 20450351 MYC Regulation of a "poor-prognosis" Metastatic Cancer Cell State Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133671 Microfluidic Isolation and Transcriptome Analysis of Serum Microvesicles Lab on a Chip. Feb, 2010 | Pubmed ID: 20126692 Coherent Oscillatory Femtosecond Dynamics in Multichannel Photodynamics of NO2 Studied by Spatially Masked Electron Imaging The Journal of Physical Chemistry. A. Mar, 2010 | Pubmed ID: 19928822 Genome-wide Transcriptome Analysis of 150 Cell Samples Integrative Biology : Quantitative Biosciences from Nano to Macro. Jan, 2009 | Pubmed ID: 20023796 Spontaneous Migration of Cancer Cells Under Conditions of Mechanical Confinement Integrative Biology : Quantitative Biosciences from Nano to Macro. Sep, 2009 | Pubmed ID: 20023765 A Short Pulse (7 Micros FWHM) and High Repetition Rate (dc-5 KHz) Cantilever Piezovalve for Pulsed Atomic and Molecular Beams The Review of Scientific Instruments. Nov, 2009 | Pubmed ID: 19947724 Cutting Edge: Electronic Counting of White Blood Cells Lab on a Chip. Oct, 2009 | Pubmed ID: 19789737 Differential Effect of Three-repeat and Four-repeat Tau on Mitochondrial Axonal Transport Journal of Neurochemistry. Oct, 2009 | Pubmed ID: 19686388 Chemical Gradient-mediated Melting Curve Analysis for Genotyping of SNPs Electrophoresis. Jul, 2009 | Pubmed ID: 19593749 Nucleation and Solidification in Static Arrays of Monodisperse Drops Lab on a Chip. Jul, 2009 | Pubmed ID: 19532960 Adaptive-control Model for Neutrophil Orientation in the Direction of Chemical Gradients Biophysical Journal. May, 2009 | Pubmed ID: 19450463 In Situ Characterization of a Cold and Short Pulsed Molecular Beam by Femtosecond Ion Imaging Physical Chemistry Chemical Physics : PCCP. May, 2009 | Pubmed ID: 19440625 Rapid Appearance of Resolvin Precursors in Inflammatory Exudates: Novel Mechanisms in Resolution Journal of Immunology (Baltimore, Md. : 1950). Dec, 2008 | Pubmed ID: 19050288 Microvortex for Focusing, Guiding and Sorting of Particles Lab on a Chip. Dec, 2008 | Pubmed ID: 19023476 Neutrophil Migration Assay from a Drop of Blood Lab on a Chip. Dec, 2008 | Pubmed ID: 19023468 TorsinA Binds the KASH Domain of Nesprins and Participates in Linkage Between Nuclear Envelope and Cytoskeleton Journal of Cell Science. Oct, 2008 | Pubmed ID: 18827015 Controlled Encapsulation of Single-cells into Monodisperse Picolitre Drops Lab on a Chip. Aug, 2008 | Pubmed ID: 18651066 Detection of Mutations in EGFR in Circulating Lung-cancer Cells The New England Journal of Medicine. Jul, 2008 | Pubmed ID: 18596266 'Living Cantilever Arrays' for Characterization of Mass of Single Live Cells in Fluids Lab on a Chip. Jul, 2008 | Pubmed ID: 18584076 Cell-cell Interaction Modulates Neuroectodermal Specification of Embryonic Stem Cells Neuroscience Letters. Jun, 2008 | Pubmed ID: 18467031 Elastomeric Microchip Electrospray Emitter for Stable Cone-jet Mode Operation in the Nanoflow Regime Analytical Chemistry. May, 2008 | Pubmed ID: 18419138 Microfluidic Leukocyte Isolation for Gene Expression Analysis in Critically Ill Hospitalized Patients Clinical Chemistry. May, 2008 | Pubmed ID: 18375483 Synthetic Microvascular Networks for Quantitative Analysis of Particle Adhesion Biomedical Microdevices. Aug, 2008 | Pubmed ID: 18327641 Equilibrium Separation and Filtration of Particles Using Differential Inertial Focusing Analytical Chemistry. Mar, 2008 | Pubmed ID: 18275222 A Microfluidic Bioreactor for Increased Active Retrovirus Output Lab on a Chip. Jan, 2008 | Pubmed ID: 18094764 Isolation of Rare Circulating Tumour Cells in Cancer Patients by Microchip Technology Nature. Dec, 2007 | Pubmed ID: 18097410 Polar Stimulation and Constrained Cell Migration in Microfluidic Channels Lab on a Chip. Dec, 2007 | Pubmed ID: 18030401 Continuous Inertial Focusing, Ordering, and Separation of Particles in Microchannels Proceedings of the National Academy of Sciences of the United States of America. Nov, 2007 | Pubmed ID: 18025477 Cell Detection and Counting Through Cell Lysate Impedance Spectroscopy in Microfluidic Devices Lab on a Chip. Jun, 2007 | Pubmed ID: 17538717 A Microchip Approach for Practical Label-free CD4+ T-cell Counting of HIV-infected Subjects in Resource-poor Settings Journal of Acquired Immune Deficiency Syndromes (1999). Jul, 2007 | Pubmed ID: 17414933 A Microfluidic Device for Practical Label-free CD4(+) T Cell Counting of HIV-infected Subjects Lab on a Chip. Feb, 2007 | Pubmed ID: 17268618 A High-throughput Microfluidic Real-time Gene Expression Living Cell Array Lab on a Chip. Jan, 2007 | Pubmed ID: 17180208 Desiccation Kinetics of Biopreservation Solutions in Microchannels Journal of Applied Physics. 2006 | Pubmed ID: 24155501 Universal Microfluidic Gradient Generator Analytical Chemistry. May, 2006 | Pubmed ID: 16689552 Cell Handling Using Microstructured Membranes Lab on a Chip. Mar, 2006 | Pubmed ID: 16511616 Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-derived Factor-1/CXCL12 Induce Tumor-specific T Cell Chemorepulsion and Escape from Immune Control Journal of Immunology (Baltimore, Md. : 1950). Mar, 2006 | Pubmed ID: 16493048 Microfluidic System for Measuring Neutrophil Migratory Responses to Fast Switches of Chemical Gradients Lab on a Chip. Feb, 2006 | Pubmed ID: 16450027 Blood-on-a-chip Annual Review of Biomedical Engineering. 2005 | Pubmed ID: 16004567 Kinetics of Intracellular Ice Formation in One-dimensional Arrays of Interacting Biological Cells Biophysical Journal. Jan, 2005 | Pubmed ID: 15475590 Single-cell Chemical Lysis in Picoliter-scale Closed Volumes Using a Microfabricated Device Analytical Chemistry. Oct, 2004 | Pubmed ID: 15481964 Parametric Analysis of Intercellular Ice Propagation During Cryosurgery, Simulated Using Monte Carlo Techniques Technology in Cancer Research & Treatment. Apr, 2004 | Pubmed ID: 15059017 Kinetics and Mechanism of Intercellular Ice Propagation in a Micropatterned Tissue Construct Biophysical Journal. Apr, 2002 | Pubmed ID: 11916845 Microstructured Devices for Optimized Microinjection and Imaging of Zebrafish Larvae Felix Ellett1, Daniel Irimia1 1BioMEMS Resource Center, Department of Surgery, Massachusetts General Hospital–Harvard Medical School–Shriners Burns Hospital JoVE 56498 발생학 Microfluidic Platform for Measuring Neutrophil Chemotaxis from Unprocessed Whole Blood Caroline N. Jones*1,2,3, Anh N. Hoang*1,2,3, Laurie Dimisko1, Bashar Hamza1, Joseph Martel1,4, Daniel Irimia1,2,3 1The BioMEMS Resource Center, Department of Surgery, Massachusetts General Hospital, 2Harvard Medical School, 3Shriners Burns Hospital, 4Harvard University School of Engineering and Applied Sciences JoVE 51215 생체공학
Microstructured Devices for Optimized Microinjection and Imaging of Zebrafish Larvae Felix Ellett1, Daniel Irimia1 1BioMEMS Resource Center, Department of Surgery, Massachusetts General Hospital–Harvard Medical School–Shriners Burns Hospital JoVE 56498 발생학
Microfluidic Platform for Measuring Neutrophil Chemotaxis from Unprocessed Whole Blood Caroline N. Jones*1,2,3, Anh N. Hoang*1,2,3, Laurie Dimisko1, Bashar Hamza1, Joseph Martel1,4, Daniel Irimia1,2,3 1The BioMEMS Resource Center, Department of Surgery, Massachusetts General Hospital, 2Harvard Medical School, 3Shriners Burns Hospital, 4Harvard University School of Engineering and Applied Sciences JoVE 51215 생체공학