Francesca Granucci Department of Biotechnology and Biosciences University of Milano-Bicocca Biography Publications Institution JoVE Articles Francesca Granucci has not added a biography. If you are Francesca Granucci and would like to personalize this page please email our Author Liaison for assistance. Publications Toll-like Receptor 4 Modulation Influences Human Neural Stem Cell Proliferation and Differentiation Cell Death & Disease. Feb, 2018 | Pubmed ID: 29449625 The Family of LPS Signal Transducers Increases: the Arrival of Chanzymes Immunity. Jan, 2018 | Pubmed ID: 29343439 Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs Frontiers in Immunology. 2017 | Pubmed ID: 29234323 Nanoparticles: "magic Bullets" for Targeting the Immune System Seminars in Immunology. Dec, 2017 | Pubmed ID: 29173493 Skin Infections Are Eliminated by Cooperation of the Fibrinolytic and Innate Immune Systems Science Immunology. Sep, 2017 | Pubmed ID: 28939652 Drug Nanocarriers to Treat Autoimmunity and Chronic Inflammatory Diseases Seminars in Immunology. Dec, 2017 | Pubmed ID: 28855088 IFN-λ Suppresses Intestinal Inflammation by Non-translational Regulation of Neutrophil Function Nature Immunology. Oct, 2017 | Pubmed ID: 28846084 Inflammatory Role of Dendritic Cells in Amyotrophic Lateral Sclerosis Revealed by an Analysis of Patients' Peripheral Blood Scientific Reports. Aug, 2017 | Pubmed ID: 28798369 Blood to Skin Recirculation of CD4 Memory T Cells Associates with Cutaneous and Systemic Manifestations of Psoriatic Disease Clinical Immunology (Orlando, Fla.). 07, 2017 | Pubmed ID: 28392462 Prolonged Contact with Dendritic Cells Turns Lymph Node-resident NK Cells into Anti-tumor Effectors EMBO Molecular Medicine. 09, 2016 | Pubmed ID: 27406819 A Role for CCR5(+)CD4 T Cells in Cutaneous Psoriasis and for CD103(+) CCR4(+) CD8 Teff Cells in the Associated Systemic Inflammation Journal of Autoimmunity. Apr, 2016 | Pubmed ID: 27068801 Cream Formulation Impact on Topical Administration of Engineered Colloidal Nanoparticles PloS One. 2015 | Pubmed ID: 25962161 "Endotoxin, TLR4 Signaling and Beyond" Molecular Immunology. Feb, 2015 | Pubmed ID: 25218433 Microbe- and Danger-induced Inflammation Molecular Immunology. Feb, 2015 | Pubmed ID: 25037632 Murein Lytic Enzyme TgaA of Bifidobacterium Bifidum MIMBb75 Modulates Dendritic Cell Maturation Through Its Cysteine- and Histidine-dependent Amidohydrolase/peptidase (CHAP) Amidase Domain Applied and Environmental Microbiology. Sep, 2014 | Pubmed ID: 24814791 RBet V 1 Immunotherapy of Sensitized Mice with Streptococcus Thermophilus As Vehicle and Adjuvant Human Vaccines & Immunotherapeutics. 2014 | Pubmed ID: 24603094 The Nature of Activatory and Tolerogenic Dendritic Cell-derived Signal 2 Frontiers in Immunology. 2014 | Pubmed ID: 24567734 Modulation of CD14 and TLR4·MD-2 Activities by a Synthetic Lipid A Mimetic Chembiochem : a European Journal of Chemical Biology. Jan, 2014 | Pubmed ID: 24339336 Wiskott-Aldrich Syndrome Protein Deficiency in Natural Killer and Dendritic Cells Affects Antitumor Immunity European Journal of Immunology. Apr, 2014 | Pubmed ID: 24338698 Modeling Leukocyte-leukocyte Non-contact Interactions in a Lymph Node PloS One. 2013 | Pubmed ID: 24204669 IL-15 Cis Presentation is Required for Optimal NK Cell Activation in Lipopolysaccharide-mediated Inflammatory Conditions Cell Reports. Sep, 2013 | Pubmed ID: 24055061 Systemically Administered DNA and Fowlpox Recombinants Expressing Four Vaccinia Virus Genes Although Immunogenic Do Not Protect Mice Against the Highly Pathogenic IHD-J Vaccinia Strain Virus Research. Dec, 2013 | Pubmed ID: 24050999 Role of CD14 in Host Protection Against Infections and in Metabolism Regulation Frontiers in Cellular and Infection Microbiology. 2013 | Pubmed ID: 23898465 Migratory Conventional Dendritic Cells in the Induction of Peripheral T Cell Tolerance Journal of Leukocyte Biology. Nov, 2013 | Pubmed ID: 23898045 The Nature of Activatory and Tolerogenic Dendritic Cell-derived Signal 2 Frontiers in Immunology. 2013 | Pubmed ID: 23882267 EFIS-EJI Ita Askonas Award. Q&A with Francesca Granucci, Winner of the EFIS-EJI Ita Askonas Award 2012 European Journal of Immunology. Nov, 2012 | Pubmed ID: 23108931 The Timing of IFNβ Production Affects Early Innate Responses to Listeria Monocytogenes and Determines the Overall Outcome of Lethal Infection PloS One. 2012 | Pubmed ID: 22912878 Migratory, and Not Lymphoid-resident, Dendritic Cells Maintain Peripheral Self-tolerance and Prevent Autoimmunity Via Induction of ITreg Cells Blood. Aug, 2012 | Pubmed ID: 22760781 Regulation and Dysregulation of Innate Immunity by NFAT Signaling Downstream of Pattern Recognition Receptors (PRRs) European Journal of Immunology. Aug, 2012 | Pubmed ID: 22706795 CD14 and NFAT Mediate Lipopolysaccharide-induced Skin Edema Formation in Mice The Journal of Clinical Investigation. May, 2012 | Pubmed ID: 22466648 Similarities and Differences of Innate Immune Responses Elicited by Smooth and Rough LPS Immunology Letters. Feb, 2012 | Pubmed ID: 22207037 CD14 Controls the LPS-induced Endocytosis of Toll-like Receptor 4 Cell. Nov, 2011 | Pubmed ID: 22078883 Vaccination with Filamentous Bacteriophages Targeting DEC-205 Induces DC Maturation and Potent Anti-tumor T-cell Responses in the Absence of Adjuvants European Journal of Immunology. Sep, 2011 | Pubmed ID: 21688262 Uniform Lipopolysaccharide (LPS)-loaded Magnetic Nanoparticles for the Investigation of LPS-TLR4 Signaling Angewandte Chemie (International Ed. in English). Jan, 2011 | Pubmed ID: 21226138 The Regulatory Role of Dendritic Cells in the Induction and Maintenance of T-cell Tolerance Autoimmunity. Feb, 2011 | Pubmed ID: 20670116 DC-ATLAS: a Systems Biology Resource to Dissect Receptor Specific Signal Transduction in Dendritic Cells Immunome Research. 2010 | Pubmed ID: 21092113 Accumulative Difference Image Protocol for Particle Tracking in Fluorescence Microscopy Tested in Mouse Lymphonodes PloS One. 2010 | Pubmed ID: 20808918 A Dairy Bacterium Displays in Vitro Probiotic Properties for the Pharyngeal Mucosa by Antagonizing Group A Streptococci and Modulating the Immune Response Infection and Immunity. Nov, 2010 | Pubmed ID: 20732995 Deciphering the Complexity of Toll-like Receptor Signaling Cellular and Molecular Life Sciences : CMLS. Dec, 2010 | Pubmed ID: 20680392 Differences in Lipopolysaccharide-induced Signaling Between Conventional Dendritic Cells and Macrophages Immunobiology. Sep-Oct, 2010 | Pubmed ID: 20579765 Regulation of Antigen Uptake, Migration, and Lifespan of Dendritic Cell by Toll-like Receptors Journal of Molecular Medicine (Berlin, Germany). Sep, 2010 | Pubmed ID: 20556351 Gene Expression Profiles Identify Inflammatory Signatures in Dendritic Cells PloS One. 2010 | Pubmed ID: 20195376 Straightforward Synthesis of Novel Akt Inhibitors Based on a Glucose Scaffold Carbohydrate Research. Jul, 2010 | Pubmed ID: 20044079 The Dendritic Cell Life Cycle Cell Cycle (Georgetown, Tex.). Dec, 2009 | Pubmed ID: 19887908 CD14 Regulates the Dendritic Cell Life Cycle After LPS Exposure Through NFAT Activation Nature. Jul, 2009 | Pubmed ID: 19525933 Generation of Murine Growth Factor-dependent Long-term Dendritic Cell Lines to Investigate Host-parasite Interactions Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19347308 Glial TLR4 Receptor As New Target to Treat Neuropathic Pain: Efficacy of a New Receptor Antagonist in a Model of Peripheral Nerve Injury in Mice Glia. Sep, 2008 | Pubmed ID: 18615568 Role of Toll Like Receptor-activated Dendritic Cells in the Development of Autoimmunity Frontiers in Bioscience : a Journal and Virtual Library. 2008 | Pubmed ID: 18508547 Image Filtering for Two-photon Deep Imaging of Lymphonodes European Biophysics Journal : EBJ. Jul, 2008 | Pubmed ID: 18389230 Central Role of Dendritic Cells in the Regulation and Deregulation of Immune Responses Cellular and Molecular Life Sciences : CMLS. Jun, 2008 | Pubmed ID: 18327662 Gene Expression Profiling of Dendritic Cells by Microarray Methods in Molecular Biology (Clifton, N.J.). 2007 | Pubmed ID: 17876096 Self-tolerance, Dendritic Cell (DC)-mediated Activation and Tissue Distribution of Natural Killer (NK) Cells Immunology Letters. May, 2007 | Pubmed ID: 17451813 Inhibition of Lipid a Stimulated Activation of Human Dendritic Cells and Macrophages by Amino and Hydroxylamino Monosaccharides Angewandte Chemie (International Ed. in English). 2007 | Pubmed ID: 17387663 Natural Killer (NK) Cell Functions Can Be Strongly Boosted by Activated Dendritic Cells (DC) European Journal of Immunology. Oct, 2006 | Pubmed ID: 17013979 Effects of Dexamethazone on LPS-induced Activationand Migration of Mouse Dendritic Cells Revealed by a Genome-wide Transcriptional Analysis European Journal of Immunology. Jun, 2006 | Pubmed ID: 16708398 Dendritic Cells in Pathogen Recognition and Induction of Immune Responses: a Functional Genomics Approach Journal of Leukocyte Biology. May, 2006 | Pubmed ID: 16641136 Induction of Peripheral T Cell Tolerance by Antigen-presenting B Cells. II. Chronic Antigen Presentation Overrules Antigen-presenting B Cell Activation Journal of Immunology (Baltimore, Md. : 1950). Apr, 2006 | Pubmed ID: 16547237 Induction of Peripheral T Cell Tolerance by Antigen-presenting B Cells. I. Relevance of Antigen Presentation Persistence Journal of Immunology (Baltimore, Md. : 1950). Apr, 2006 | Pubmed ID: 16547236 Synthesis and Biological Evaluation of Novel Lipid A Antagonists Bioorganic & Medicinal Chemistry. Jan, 2006 | Pubmed ID: 16203155 Dendritic Cell Biology Advances in Immunology. 2005 | Pubmed ID: 16227091 TLR-dependent Activation Stimuli Associated with Th1 Responses Confer NK Cell Stimulatory Capacity to Mouse Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Jul, 2005 | Pubmed ID: 15972660 Differential Expression Regulation of the Alpha and Beta Subunits of the PA28 Proteasome Activator in Mature Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Jun, 2005 | Pubmed ID: 15944286 A Critical Role for Lipophosphoglycan in Proinflammatory Responses of Dendritic Cells to Leishmania Mexicana European Journal of Immunology. Feb, 2005 | Pubmed ID: 15657947 Dendritic Cell-derived IL-2 Production is Regulated by IL-15 in Humans and in Mice Blood. Jan, 2005 | Pubmed ID: 15353479 A Power Law Global Error Model for the Identification of Differentially Expressed Genes in Microarray Data BMC Bioinformatics. 2004 | Pubmed ID: 15606915 A Central Role for Tissue-resident Dendritic Cells in Innate Responses Trends in Immunology. Dec, 2004 | Pubmed ID: 15530834 The European Dimension for the Mouse Genome Mutagenesis Program Nature Genetics. Sep, 2004 | Pubmed ID: 15340424 A Contribution of Mouse Dendritic Cell-derived IL-2 for NK Cell Activation The Journal of Experimental Medicine. Aug, 2004 | Pubmed ID: 15289500 The Regulatory Role of Dendritic Cells in the Immune Response International Archives of Allergy and Immunology. Jul, 2004 | Pubmed ID: 15178886 A Type I IFN-dependent Pathway Induced by Schistosoma Mansoni Eggs in Mouse Myeloid Dendritic Cells Generates an Inflammatory Signature Journal of Immunology (Baltimore, Md. : 1950). Mar, 2004 | Pubmed ID: 14978105 The Scavenger Receptor MARCO Mediates Cytoskeleton Rearrangements in Dendritic Cells and Microglia Blood. Oct, 2003 | Pubmed ID: 12842997 The Immune Response is Initiated by Dendritic Cells Via Interaction with Microorganisms and Interleukin-2 Production The Journal of Infectious Diseases. Jun, 2003 | Pubmed ID: 12792850 Dendritic Cell Regulation of Immune Responses: a New Role for Interleukin 2 at the Intersection of Innate and Adaptive Immunity The EMBO Journal. Jun, 2003 | Pubmed ID: 12773371 Early IL-2 Production by Mouse Dendritic Cells is the Result of Microbial-induced Priming Journal of Immunology (Baltimore, Md. : 1950). May, 2003 | Pubmed ID: 12734352 Interactions of Bacterial Pathogens with Dendritic Cells During Invasion of Mucosal Surfaces Current Opinion in Microbiology. Feb, 2003 | Pubmed ID: 12615223 Opinion: Interpretation of the Complexity of Innate Immune Responses by Functional Genomics Nature Reviews. Immunology. Nov, 2002 | Pubmed ID: 12415311 Toll-like Receptor 4 is Not Required for the Full Maturation of Dendritic Cells or for the Degradation of Gram-negative Bacteria European Journal of Immunology. Oct, 2002 | Pubmed ID: 12355432 Granulocyte-macrophage Colony-stimulating Factor Induces an Expression Program in Neonatal Microglia That Primes Them for Antigen Presentation Journal of Immunology (Baltimore, Md. : 1950). Sep, 2002 | Pubmed ID: 12193691 IL-2 Mediates Adjuvant Effect of Dendritic Cells Trends in Immunology. Apr, 2002 | Pubmed ID: 11923103 Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses William Santus1, Francesca Mingozzi1, Marina Vai1, Francesca Granucci*1, Ivan Zanoni*1,2 1Department of Biotechnology and Biosciences, University of Milano-Bicocca, 2Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital JoVE 57574 면역학 및 감염병학 Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions Achille Broggi1,2, Clara Cigni1, Ivan Zanoni1,2,3, Francesca Granucci1,3 1Department of Biotechnology and Biosciences, University of Milano-Bicocca, 2Boston Children's Hospital, Division of Gastroenterology, Harvard Medical School, 3Humanitas Clinical and Research Center JoVE 52589 면역학 및 감염병학
Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses William Santus1, Francesca Mingozzi1, Marina Vai1, Francesca Granucci*1, Ivan Zanoni*1,2 1Department of Biotechnology and Biosciences, University of Milano-Bicocca, 2Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital JoVE 57574 면역학 및 감염병학
Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions Achille Broggi1,2, Clara Cigni1, Ivan Zanoni1,2,3, Francesca Granucci1,3 1Department of Biotechnology and Biosciences, University of Milano-Bicocca, 2Boston Children's Hospital, Division of Gastroenterology, Harvard Medical School, 3Humanitas Clinical and Research Center JoVE 52589 면역학 및 감염병학