Geert Berx Department of Biomedical Molecular Biology Ghent University Biography Publications Institution JoVE Articles Geert Berx has not added a biography. If you are Geert Berx and would like to personalize this page please email our Author Liaison for assistance. Publications EV-TRACK: Transparent Reporting and Centralizing Knowledge in Extracellular Vesicle Research Nature Methods. Feb, 2017 | Pubmed ID: 28245209 Oncogenic ZEB2 Activation Drives Sensitivity Toward KDM1A Inhibition in T-cell Acute Lymphoblastic Leukemia Blood. Feb, 2017 | Pubmed ID: 28069602 Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells Stem Cells (Dayton, Ohio). Mar, 2017 | Pubmed ID: 27739137 Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation The Journal of Investigative Dermatology. Feb, 2017 | Pubmed ID: 27725202 P120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification PLoS Genetics. Aug, 2016 | Pubmed ID: 27556156 Tissue Factor Induced by Epithelial-Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells Cancer Research. Jul, 2016 | Pubmed ID: 27221703 The Transcription Factor Zeb2 Regulates Development of Conventional and Plasmacytoid DCs by Repressing Id2 The Journal of Experimental Medicine. May, 2016 | Pubmed ID: 27185854 Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity Cell Reports. Apr, 2016 | Pubmed ID: 27050509 LIN28B is Over-expressed in Specific Subtypes of Pediatric Leukemia and Regulates LncRNA H19 Haematologica. Jun, 2016 | Pubmed ID: 26969084 Development and Characterization of a New Human Hepatic Cell Line EXCLI Journal. 2015 | Pubmed ID: 26869867 Terminal NK Cell Maturation is Controlled by Concerted Actions of T-bet and Zeb2 and is Essential for Melanoma Rejection The Journal of Experimental Medicine. Nov, 2015 | Pubmed ID: 26503444 NBPF1, a Tumor Suppressor Candidate in Neuroblastoma, Exerts Growth Inhibitory Effects by Inducing a G1 Cell Cycle Arrest BMC Cancer. May, 2015 | Pubmed ID: 25958384 Tumor-environment Biomimetics Delay Peritoneal Metastasis Formation by Deceiving and Redirecting Disseminated Cancer Cells Biomaterials. Jun, 2015 | Pubmed ID: 25907048 Snai1 Regulates Cell Lineage Allocation and Stem Cell Maintenance in the Mouse Intestinal Epithelium The EMBO Journal. May, 2015 | Pubmed ID: 25759216 ZEB2 Drives Immature T-cell Lymphoblastic Leukaemia Development Via Enhanced Tumour-initiating Potential and IL-7 Receptor Signalling Nature Communications. Jan, 2015 | Pubmed ID: 25565005 Melanoma Cells Revive an Embryonic Transcriptional Network to Dictate Phenotypic Heterogeneity Frontiers in Oncology. 2014 | Pubmed ID: 25538895 Deregulation of the Replisome Factor MCMBP Prompts Oncogenesis in Colorectal Carcinomas Through Chromosomal Instability Neoplasia (New York, N.Y.). Sep, 2014 | Pubmed ID: 25246271 Strategies for Immortalization of Primary Hepatocytes Journal of Hepatology. Oct, 2014 | Pubmed ID: 24911463 ZEB2-transgene Expression in the Epidermis Compromises the Integrity of the Epidermal Barrier Through the Repression of Different Tight Junction Proteins Cellular and Molecular Life Sciences : CMLS. Sep, 2014 | Pubmed ID: 24573695 Cadherins and Epithelial-to-mesenchymal Transition Progress in Molecular Biology and Translational Science. 2013 | Pubmed ID: 23481201 Interplay Between KLF4 and ZEB2/SIP1 in the Regulation of E-cadherin Expression Biochemical and Biophysical Research Communications. Feb, 2013 | Pubmed ID: 23376074 Regulatory Networks Defining EMT During Cancer Initiation and Progression Nature Reviews. Cancer. Feb, 2013 | Pubmed ID: 23344542 Directed Migration of Cortical Interneurons Depends on the Cell-autonomous Action of Sip1 Neuron. Jan, 2013 | Pubmed ID: 23312517 Gene Expression Profiling to Dissect the Complexity of Cancer Biology: Pitfalls and Promise Seminars in Cancer Biology. Jun, 2012 | Pubmed ID: 22459768 Concepts of Metastasis in Flux: the Stromal Progression Model Seminars in Cancer Biology. Jun, 2012 | Pubmed ID: 22374376 Evolutionary Functional Analysis and Molecular Regulation of the ZEB Transcription Factors Cellular and Molecular Life Sciences : CMLS. Aug, 2012 | Pubmed ID: 22349261 Identification of Putative Cancer Genes Through Data Integration and Comparative Genomics Between Plants and Humans Cellular and Molecular Life Sciences : CMLS. Jun, 2012 | Pubmed ID: 22218400 The EMT Regulator Zeb2/Sip1 is Essential for Murine Embryonic Hematopoietic Stem/progenitor Cell Differentiation and Mobilization Blood. May, 2011 | Pubmed ID: 21355089 Key Signalling Nodes in Mammary Gland Development and Cancer. The Snail1-Twist1 Conspiracy in Malignant Breast Cancer Progression Breast Cancer Research : BCR. 2010 | Pubmed ID: 20594364 Module Network Inference from a Cancer Gene Expression Data Set Identifies MicroRNA Regulated Modules PloS One. Apr, 2010 | Pubmed ID: 20418949 Regulation of P63 Isoforms by Snail and Slug Transcription Factors in Human Squamous Cell Carcinoma The American Journal of Pathology. Apr, 2010 | Pubmed ID: 20150431 The MCM-binding Protein ETG1 Aids Sister Chromatid Cohesion Required for Postreplicative Homologous Recombination Repair PLoS Genetics. Jan, 2010 | Pubmed ID: 20090939 Involvement of Members of the Cadherin Superfamily in Cancer Cold Spring Harbor Perspectives in Biology. Dec, 2009 | Pubmed ID: 20457567 Alternatively Activated Macrophages Engage in Homotypic and Heterotypic Interactions Through IL-4 and Polyamine-induced E-cadherin/catenin Complexes Blood. Nov, 2009 | Pubmed ID: 19726720 Transforming Growth Factor-beta and Mutant P53 Conspire to Induce Metastasis by Antagonizing P63: a (ternary) Complex Affair Breast Cancer Research : BCR. 2009 | Pubmed ID: 19664188 Efficient Mouse Transgenesis Using Gateway-compatible ROSA26 Locus Targeting Vectors and F1 Hybrid ES Cells Nucleic Acids Research. Apr, 2009 | Pubmed ID: 19279185 Molecular and Pathological Signatures of Epithelial-mesenchymal Transitions at the Cancer Invasion Front Histochemistry and Cell Biology. Sep, 2008 | Pubmed ID: 18648847 A Constitutional Translocation T(1;17)(p36.2;q11.2) in a Neuroblastoma Patient Disrupts the Human NBPF1 and ACCN1 Genes PloS One. May, 2008 | Pubmed ID: 18493581 Transforming Growth Factor-beta1-mediated Slug and Snail Transcription Factor Up-regulation Reduces the Density of Langerhans Cells in Epithelial Metaplasia by Affecting E-cadherin Expression The American Journal of Pathology. May, 2008 | Pubmed ID: 18385519 Pre-EMTing Metastasis? Recapitulation of Morphogenetic Processes in Cancer Clinical & Experimental Metastasis. 2007 | Pubmed ID: 17978854 Direct Repression of Cyclin D1 by SIP1 Attenuates Cell Cycle Progression in Cells Undergoing an Epithelial Mesenchymal Transition Molecular Biology of the Cell. Nov, 2007 | Pubmed ID: 17855508 VHL Promotes E2 Box-dependent E-cadherin Transcription by HIF-mediated Regulation of SIP1 and Snail Molecular and Cellular Biology. Jan, 2007 | Pubmed ID: 17060462 E-cadherin Regulates Human Nanos1, Which Interacts with P120ctn and Induces Tumor Cell Migration and Invasion Cancer Research. Oct, 2006 | Pubmed ID: 17047063 A Transient, EMT-linked Loss of Basement Membranes Indicates Metastasis and Poor Survival in Colorectal Cancer Gastroenterology. Sep, 2006 | Pubmed ID: 16952552 Snail in the Frame of Malignant Tumor Recurrence Breast Cancer Research : BCR. 2006 | Pubmed ID: 16834762 SIP1/ZEB2 Induces EMT by Repressing Genes of Different Epithelial Cell-cell Junctions Nucleic Acids Research. 2005 | Pubmed ID: 16314317 The Transcription Factor Snail Induces Tumor Cell Invasion Through Modulation of the Epithelial Cell Differentiation Program Cancer Research. Jul, 2005 | Pubmed ID: 16024625 Unraveling Signalling Cascades for the Snail Family of Transcription Factors Cellular Signalling. May, 2005 | Pubmed ID: 15683729 DeltaEF1 is a Transcriptional Repressor of E-cadherin and Regulates Epithelial Plasticity in Breast Cancer Cells Oncogene. Mar, 2005 | Pubmed ID: 15674322 GATA-4 and MEF2C Transcription Factors Control the Tissue-specific Expression of the AlphaT-catenin Gene CTNNA3 Nucleic Acids Research. 2004 | Pubmed ID: 15302915 Combined Subtractive CDNA Cloning and Array CGH: an Efficient Approach for Identification of Overexpressed Genes in DNA Amplicons BMC Genomics. Feb, 2004 | Pubmed ID: 15018647 Functional and Molecular Characterization of the Epithelioid to Round Transition in Human Colorectal Cancer LoVo Cells Oncogene. Oct, 2003 | Pubmed ID: 14562048 Identification of Excretory-secretory Products of Larval and Adult Ostertagia Ostertagi by Immunoscreening of CDNA Libraries Molecular and Biochemical Parasitology. Feb, 2003 | Pubmed ID: 12615319 Localization of the 17q Breakpoint of a Constitutional 1;17 Translocation in a Patient with Neuroblastoma Within a 25-kb Segment Located Between the ACCN1 and TLK2 Genes and Near the Distal Breakpoints of Two Microdeletions in Neurofibromatosis Type 1 Patients Genes, Chromosomes & Cancer. Oct, 2002 | Pubmed ID: 12203774 Smad4 Induces the Tumor Suppressor E-cadherin and P-cadherin in Colon Carcinoma Cells Oncogene. Sep, 2002 | Pubmed ID: 12203117 Структурно-функциональные исследования в мышиных эмбриональных стволовых клеток Использование Рекомбиназа-опосредованного кассетный Обмен Tim Pieters1,2,3,4, Lieven Haenebalcke1,2, Kenneth Bruneel1,2,4, Niels Vandamme1,2,4, Tino Hochepied1,2, Jolanda van Hengel5, Dagmar Wirth6, Geert Berx1,2,4, Jody J. Haigh7, Frans van Roy1,2,4, Steven Goossens1,2,3,4 1Department of Biomedical Molecular Biology, Ghent University, 2Inflammation Research Center, VIB, 3Center for Medical Genetics, Ghent University Hospital, 4Cancer Research Institute Ghent (CRIG), 5Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, 6Helmholtz Center for Infection Research, 7Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred Health Alfred Centre JoVE 55575 발생학
Структурно-функциональные исследования в мышиных эмбриональных стволовых клеток Использование Рекомбиназа-опосредованного кассетный Обмен Tim Pieters1,2,3,4, Lieven Haenebalcke1,2, Kenneth Bruneel1,2,4, Niels Vandamme1,2,4, Tino Hochepied1,2, Jolanda van Hengel5, Dagmar Wirth6, Geert Berx1,2,4, Jody J. Haigh7, Frans van Roy1,2,4, Steven Goossens1,2,3,4 1Department of Biomedical Molecular Biology, Ghent University, 2Inflammation Research Center, VIB, 3Center for Medical Genetics, Ghent University Hospital, 4Cancer Research Institute Ghent (CRIG), 5Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, 6Helmholtz Center for Infection Research, 7Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred Health Alfred Centre JoVE 55575 발생학