Gertjan J.L. Kaspers Academy & Outreach Princess Máxima Center for pediatric oncology Biography Publications Institution JoVE Articles Gertjan J.L. KaspersProfessor and Director Professor Gertjan Kaspers became pediatric oncologist in 2000, and has been Professor in Pediatric Oncology since 2006, at Amsterdam UMC. Since 2013 onwards, he is Director of the Academy & Outreach department of Princess Máxima Center, the Dutch center of excellence for children with cancer. He supervises research mainly on leukemias and on pediatric oncology in developing countries, as well as research on brain tumors, quality of life and late effects. He is promotor of 20 PhD students and trained 31 PhD students successfully. He is involved in several “outreach” projects, aiming at improved outcome for children with cancer in LMIC. He initiated and chairs the I-BFM-SG Task Force on Outreach and the Foundation World Child Cancer NL. Gertjan Kaspers is visiting Professor at UZ Gent (Belgium), MTRH in Eldoret (Kenya) and UGM in Yogyakarta (Indonesia). Publications Harnessing Gene Expression Profiles for the Identification of Ex Vivo Drug Response Genes in Pediatric Acute Myeloid Leukemia Cancers. May, 2020 | Pubmed ID: 32429253 Glucocorticoid Resistant Pediatric Acute Lymphoblastic Leukemia Samples Display Altered Splicing Profile and Vulnerability to Spliceosome Modulation Cancers. Mar, 2020 | Pubmed ID: 32204435 Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2020 | Pubmed ID: 32165429 Actigraphic Estimates of Sleep and the Sleep-wake Rhythm, and 6-sulfatoxymelatonin Levels in Healthy Dutch Children Chronobiology International. Mar, 2020 | Pubmed ID: 32126835 High Prevalence of Parent-reported Sleep Problems in Pediatric Patients with Acute Lymphoblastic Leukemia After Induction Therapy Pediatric Blood & Cancer. 04, 2020 | Pubmed ID: 31944548 Sleep-wake Rhythm Disruption is Associated with Cancer-related Fatigue in Pediatric Acute Lymphoblastic Leukemia Sleep. Jun, 2020 | Pubmed ID: 31889198 Causes of Early Death and Treatment-related Death in Newly Diagnosed Pediatric Acute Myeloid Leukemia: Recent Experiences of the Dutch Childhood Oncology Group Pediatric Blood & Cancer. 04, 2020 | Pubmed ID: 31872548 Determinants of Health-related Quality of Life Proxy Rating Disagreement Between Caregivers of Children with Cancer Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. Apr, 2020 | Pubmed ID: 31820207 MEK/MELK Inhibition and Blood-brain Barrier Deficiencies in Atypical Teratoid/rhabdoid Tumors Neuro-oncology. 01, 2020 | Pubmed ID: 31504799 Development of an Evidence-based Decision Aid on Complementary and Alternative Medicine (CAM) and Pain for Parents of Children with Cancer Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. May, 2020 | Pubmed ID: 31493135 Celastrol-induced Degradation of FANCD2 Sensitizes Pediatric High-grade Gliomas to the DNA-crosslinking Agent Carboplatin EBioMedicine. Dec, 2019 | Pubmed ID: 31735550 Concurrence of Sleep Problems and Distress: Prevalence and Determinants in Parents of Children with Cancer European Journal of Psychotraumatology. Month, 2019 | Pubmed ID: 31448065 Longitudinal Development of Cancer-related Fatigue and Physical Activity in Childhood Cancer Patients Pediatric Blood & Cancer. 12, 2019 | Pubmed ID: 31436372 Preclinical Therapeutic Targets in Diffuse Midline Glioma Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 05, 2019 | Pubmed ID: 31202081 Splicing Modulation As Novel Therapeutic Strategy Against Diffuse Malignant Peritoneal Mesothelioma EBioMedicine. Jan, 2019 | Pubmed ID: 30581150 An Efficient Method for the Transduction of Primary Pediatric Glioma Neurospheres MethodsX. Month, 2018 | Pubmed ID: 30622915 Effects of a Combined Physical and Psychosocial Training for Children with Cancer: a Randomized Controlled Trial BMC Cancer. Dec, 2018 | Pubmed ID: 30587148 MELK Inhibition in Diffuse Intrinsic Pontine Glioma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 11, 2018 | Pubmed ID: 30061363 Signaling Pathways and Mesenchymal Transition in Pediatric High-grade Glioma Cellular and Molecular Life Sciences : CMLS. Mar, 2018 | Pubmed ID: 29164272 Deceptive Morphologic and Epigenetic Heterogeneity in Diffuse Intrinsic Pontine Glioma Oncotarget. 09, 2017 | Pubmed ID: 28947983 Culture Methods of Diffuse Intrinsic Pontine Glioma Cells Determine Response to Targeted Therapies Experimental Cell Research. 11, 2017 | Pubmed ID: 28947132 Multiregional Tumor Drug-uptake Imaging by PET and Microvascular Morphology in End-stage Diffuse Intrinsic Pontine Glioma Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2017 | Pubmed ID: 28818988 A Chemical Screen for Medulloblastoma Identifies Quercetin As a Putative Radiosensitizer Oncotarget. Jun, 2016 | Pubmed ID: 26967057 Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis Molecular & Cellular Proteomics : MCP. Apr, 2016 | Pubmed ID: 26801919 Methotrexate Resistance in Relation to Treatment Outcome in Childhood Acute Lymphoblastic Leukemia Journal of Hematology & Oncology. May, 2015 | Pubmed ID: 26022503 Identification of Temozolomide Resistance Factors in Glioblastoma Via Integrative MiRNA/mRNA Regulatory Network Analysis Scientific Reports. Jun, 2014 | Pubmed ID: 24919120 EFEMP1 Induces γ-secretase/Notch-mediated Temozolomide Resistance in Glioblastoma Oncotarget. Jan, 2014 | Pubmed ID: 24495907 PARP Inhibition Sensitizes Childhood High Grade Glioma, Medulloblastoma and Ependymoma to Radiation Oncotarget. Dec, 2011 | Pubmed ID: 22184287 Attenuated AMPA Receptor Expression Allows Glioblastoma Cell Survival in Glutamate-rich Environment PloS One. Jun, 2009 | Pubmed ID: 19536293 Role of Tyrosine Phosphatase Inhibitors in Cancer Treatment with Emphasis on SH2 Domain-containing Tyrosine Phosphatases (SHPs) Anti-cancer Agents in Medicinal Chemistry. Feb, 2009 | Pubmed ID: 19199865 げっ歯類における血液脳関門開口のためのハイスループット画像誘導定型神経ナビゲーションと集中超音波システム Rianne Haumann*1,2, Elvin ’t Hart*2, Marc P. P. Derieppe2, Helena C. Besse3, Gertjan J. L. Kaspers1,2, Eelco Hoving2, Dannis G. van Vuurden1,2, Esther Hulleman1,2, Mario Ries3 1Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Oncology, Cancer Center Amsterdam, 2Princess Máxima Center for Pediatric Oncology, 3Imaging Division, Utrecht University JoVE 61269 신경과학
げっ歯類における血液脳関門開口のためのハイスループット画像誘導定型神経ナビゲーションと集中超音波システム Rianne Haumann*1,2, Elvin ’t Hart*2, Marc P. P. Derieppe2, Helena C. Besse3, Gertjan J. L. Kaspers1,2, Eelco Hoving2, Dannis G. van Vuurden1,2, Esther Hulleman1,2, Mario Ries3 1Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Oncology, Cancer Center Amsterdam, 2Princess Máxima Center for Pediatric Oncology, 3Imaging Division, Utrecht University JoVE 61269 신경과학