Heather E. Fleming Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology Biography Publications Institution JoVE Articles Heather E. Fleming has not added a biography. If you are Heather E. Fleming and would like to personalize this page please email our Author Liaison for assistance. Publications CRISPR-Cas-amplified Urinary Biomarkers for Multiplexed and Portable Cancer Diagnostics Nature Nanotechnology. Jul, 2023 | Pubmed ID: 37095220 Conditional Antimicrobial Peptide Therapeutics ACS Nano. Oct, 2022 | Pubmed ID: 35980829 A Vascularized Model of the Human Liver Mimics Regenerative Responses Proceedings of the National Academy of Sciences of the United States of America. Jul, 2022 | Pubmed ID: 35763565 A Single-cell Liver Atlas of Plasmodium Vivax Infection Cell Host & Microbe. Jul, 2022 | Pubmed ID: 35443155 Virtual Undergraduate Research Experiences: More Than a Pandemic Stopgap Med (New York, N.Y.). Feb, 2021 | Pubmed ID: 35187514 Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection ACS Synthetic Biology. Sep, 2021 | Pubmed ID: 34464083 Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function ACS Chemical Biology. Sep, 2021 | Pubmed ID: 34427427 Microenvironment-triggered Multimodal Precision Diagnostics Nature Materials. Oct, 2021 | Pubmed ID: 34267368 Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers Advanced Functional Materials. Nov, 2020 | Pubmed ID: 33776613 Urinary Detection of Lung Cancer in Mice Via Noninvasive Pulmonary Protease Profiling Science Translational Medicine. Apr, 2020 | Pubmed ID: 32238573 Non-viral Delivery of CRISPR/Cas9 Complex Using CRISPR-GPS Nanocomplexes Nanoscale. Nov, 2019 | Pubmed ID: 31670340 Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers Cell Metabolism. Mar, 2019 | Pubmed ID: 30840913 Protease Activity Sensors Noninvasively Classify Bacterial Infections and Antibiotic Responses EBioMedicine. Dec, 2018 | Pubmed ID: 30503861 In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites Cell Host & Microbe. Mar, 2018 | Pubmed ID: 29478773 In Situ Expansion of Engineered Human Liver Tissue in a Mouse Model of Chronic Liver Disease Science Translational Medicine. Jul, 2017 | Pubmed ID: 28724577 Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors Angewandte Chemie (International Ed. in English). Sep, 2016 | Pubmed ID: 27554600 Micropatterned Coculture of Primary Human Hepatocytes and Supportive Cells for the Study of Hepatotropic Pathogens Nature Protocols. Dec, 2015 | Pubmed ID: 26584444 Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging Audrey E. Van Heest1, Feiyang Deng1, Renee T. Zhao2, Nour Saida Harzallah2,3, Heather E. Fleming3,4, Sangeeta N. Bhatia2,3,4,5,6,7,8, Liangliang Hao1,2,3 1Department of Biomedical Engineering, Boston University, 2Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 3Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 4Howard Hughes Medical Institute, 5Broad Institute of Massachusetts Institute of Technology and Harvard, 6Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 7Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 8Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School JoVE 66189 생체공학
Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging Audrey E. Van Heest1, Feiyang Deng1, Renee T. Zhao2, Nour Saida Harzallah2,3, Heather E. Fleming3,4, Sangeeta N. Bhatia2,3,4,5,6,7,8, Liangliang Hao1,2,3 1Department of Biomedical Engineering, Boston University, 2Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 3Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 4Howard Hughes Medical Institute, 5Broad Institute of Massachusetts Institute of Technology and Harvard, 6Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 7Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 8Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School JoVE 66189 생체공학