Huijuan Shi Shanghai-MOST Key Laboratory of Health and Disease Genomics, NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), School of Pharmacy Fudan University Biography Publications Institution JoVE Articles Huijuan Shi has not added a biography. If you are Huijuan Shi and would like to personalize this page please email our Author Liaison for assistance. Publications Targeted Proteomics-determined Multi-biomarker Profiles Developed Classifier for Prognosis and Immunotherapy Responses of Advanced Cervical Cancer Frontiers in Immunology. 2024 | Pubmed ID: 38835778 Divergent Composition and Transposon-silencing Activity of Small RNAs in Mammalian Oocytes Genome Biology. Mar, 2024 | Pubmed ID: 38532500 Loss of ACTL7A Causes Small Head Sperm by Defective Acrosome-acroplaxome-manchette Complex Reproductive Biology and Endocrinology : RB&E. Sep, 2023 | Pubmed ID: 37667331 Increased Serine Synthesis in Cumulus Cells of Young Infertile Women with Diminished Ovarian Reserve Human Reproduction (Oxford, England). Sep, 2023 | Pubmed ID: 37533289 Experimental and Molecular Support for Cfap70 As a Causative Gene of 'multiple Morphological Abnormalities of the Flagella' with Male Infertility† Biology of Reproduction. Oct, 2023 | Pubmed ID: 37458246 The PIWI-specific Insertion Module Helps Load Longer PiRNAs for Translational Activation Essential for Male Fertility Science China. Life Sciences. Jul, 2023 | Pubmed ID: 37335463 Relevance of PUFA-derived Metabolites in Seminal Plasma to Male Infertility Frontiers in Endocrinology. 2023 | Pubmed ID: 37284213 Escaping Behavior of Sperms on the Biomimetic Oviductal Surface Analytical Chemistry. Jan, 2023 | Pubmed ID: 36655581 Effect of Advanced Paternal Age on Reproductive Outcomes in IVF Cycles of Non-male-factor Infertility: a Retrospective Cohort Study Asian Journal of Andrology. 2023 | Pubmed ID: 35775508 Associations of Perfluoroalkyl and Polyfluoroalkyl Substances with Gestational Hypertension and Blood Pressure During Pregnancy: A Cohort Study Environmental Research. Dec, 2022 | Pubmed ID: 36088993 LLPS of FXR1 Drives Spermiogenesis by Activating Translation of Stored MRNAs Science (New York, N.Y.). Aug, 2022 | Pubmed ID: 35951695 Mitochondrial Dysfunction in Cumulus Cells is Related to Decreased Reproductive Capacity in Advanced-age Women Fertility and Sterility. Aug, 2022 | Pubmed ID: 35637023 Sperm-specific Protein ACTL7A As a Biomarker for Fertilization Outcomes of Assisted Reproductive Technology Asian Journal of Andrology. 2022 | Pubmed ID: 35532568 Complete Androgen Insensitivity Syndrome Caused by a Novel Mutation in the Androgen Receptor Gene and Its Mechanism Clinica Chimica Acta; International Journal of Clinical Chemistry. Jun, 2022 | Pubmed ID: 35351434 Cervix Chip Mimicking Cervical Microenvironment for Quantifying Sperm Locomotion Biosensors & Bioelectronics. May, 2022 | Pubmed ID: 35151944 Assessment of the Health Status of Middle-aged and Elderly Men with Head Scale, SF-36, IIEF5, AMS, and IPSS BMC Geriatrics. Nov, 2021 | Pubmed ID: 34772361 Body Mass Index Changes in Relation to Male Reproductive Hormones: Longitudinal Results From a Community-Based Cohort Study American Journal of Men's Health. 2021 | Pubmed ID: 34581214 Effects of Low Lead Exposure on Sperm Quality and Sperm DNA Methylation in Adult Men Cell & Bioscience. Jul, 2021 | Pubmed ID: 34344450 Regulation of the Mammalian Maternal-to-embryonic Transition by Eukaryotic Translation Initiation Factor 4E Development (Cambridge, England). Jun, 2021 | Pubmed ID: 34013332 Reply to Lack of Evidence for a Role of PIWIL1 Variants in Human Male Infertility Cell. Apr, 2021 | Pubmed ID: 33861958 Serum Sex Hormone-binding Globulin is Associated with Symptomatic Late-onset Hypogonadism in Aging Rural Males: a Community-based Study Sexual Health. May, 2021 | Pubmed ID: 33715769 Association of Hypogonadism Symptoms and Serum Hormones in Aging Males Andrologia. Jun, 2021 | Pubmed ID: 33599350 Disruption in Causes Acrosomal Ultrastructural Defects in Human and Mouse Sperm As a Novel Male Factor Inducing Early Embryonic Arrest Science Advances. Aug, 2020 | Pubmed ID: 32923619 A Diagnostic Model to Improve the Predictability of Natural Pregnancy Potential in Patients with Oligoasthenospermia Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. Sep, 2020 | Pubmed ID: 32890392 Prohibitin (PHB) Interacts with AKT in Mitochondria to Coordinately Modulate Sperm Motility Asian Journal of Andrology. 2020 | Pubmed ID: 32859869 PHB Regulates Meiotic Recombination Via JAK2-mediated Histone Modifications in Spermatogenesis Nucleic Acids Research. May, 2020 | Pubmed ID: 32232334 MicroRNA Expression Profile Analysis in Sperm Reveals Hsa-mir-191 As an Auspicious Omen of in Vitro Fertilization BMC Genomics. Feb, 2020 | Pubmed ID: 32066367 LARP7-Mediated U6 SnRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice Molecular Cell. Mar, 2020 | Pubmed ID: 32017896 Joint Utilization of Genetic Analysis and Semi-cloning Technology Reveals a Digenic Etiology of Müllerian Anomalies Cell Research. Jan, 2020 | Pubmed ID: 31628433 A Translation-Activating Function of MIWI/piRNA During Mouse Spermiogenesis Cell. Dec, 2019 | Pubmed ID: 31835033 Association of UHRF1 Gene Polymorphisms with Oligospermia in Chinese Males Journal of Assisted Reproduction and Genetics. Dec, 2019 | Pubmed ID: 31802345 Association of Sperm Methylation at , Four Candidate Genes, and Nicotine/Alcohol Exposure With the Risk of Infertility Frontiers in Genetics. 2019 | Pubmed ID: 31681430 Longitudinal Trends of AMS and IIEF-5 Scores in Randomly-Selected Community Men 40 to 80 Years Old: Preliminary Results The Journal of Sexual Medicine. Oct, 2019 | Pubmed ID: 31447383 Identification of Small Non-coding RNAs As Sperm Quality Biomarkers for in Vitro Fertilization Cell Discovery. 2019 | Pubmed ID: 30992999 Author Correction: CRISPR-Cas9-mediated Base-editing Screening in Mice Identifies DND1 Amino Acids That Are Critical for Primordial Germ Cell Development Nature Cell Biology. Mar, 2019 | Pubmed ID: 30718859 Exposure of Environmental Bisphenol A in Relation to Routine Sperm Parameters and Sperm Movement Characteristics Among Fertile Men Scientific Reports. Dec, 2018 | Pubmed ID: 30510208 CRISPR-Cas9-mediated Base-editing Screening in Mice Identifies DND1 Amino Acids That Are Critical for Primordial Germ Cell Development Nature Cell Biology. Nov, 2018 | Pubmed ID: 30275529 Association of the Peripheral Blood Levels of Circulating MicroRNAs with Both Recurrent Miscarriage and the Outcomes of Embryo Transfer in an in Vitro Fertilization Process Journal of Translational Medicine. Jul, 2018 | Pubmed ID: 29973278 Comparative Analysis of Human Sperm Glycocalyx from Different Freezability Ejaculates by Lectin Microarray and Identification of ABA As Sperm Freezability Biomarker Clinical Proteomics. 2018 | Pubmed ID: 29719495 EMC10 Governs Male Fertility Via Maintaining Sperm Ion Balance Journal of Molecular Cell Biology. Dec, 2018 | Pubmed ID: 29659949 Disruption of Ssp411 Causes Impaired Sperm Head Formation and Male Sterility in Mice Biochimica Et Biophysica Acta. General Subjects. Mar, 2018 | Pubmed ID: 29247744 Increased Expression of NDRG3 in Mouse Uterus During Embryo Implantation and in Mouse Endometrial Stromal Cells During In Vitro Decidualization Reproductive Sciences (Thousand Oaks, Calif.). Aug, 2018 | Pubmed ID: 29096585 Reproductive Effects of Cadmium on Sperm Function and Early Embryonic Development in Vitro PloS One. 2017 | Pubmed ID: 29095856 The Impact of Age, BMI and Sex Hormone on Aging Males' Symptoms and the International Index of Erectile Function Scores The Aging Male : the Official Journal of the International Society for the Study of the Aging Male. Dec, 2017 | Pubmed ID: 28780904 Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange During Spermiogenesis Cell. Jun, 2017 | Pubmed ID: 28552346 A Sequence of 28S RRNA-derived Small RNAs is Enriched in Mature Sperm and Various Somatic Tissues and Possibly Associates with Inflammation Journal of Molecular Cell Biology. Jun, 2017 | Pubmed ID: 28486659 The Association Between Exposure to Environmental Bisphenol A and Gonadotropic Hormone Levels Among Men PloS One. 2017 | Pubmed ID: 28085949 Prohibitin Involvement in the Generation of Mitochondrial Superoxide at Complex I in Human Sperm Journal of Cellular and Molecular Medicine. Jan, 2017 | Pubmed ID: 27558591 A Human Lectin Microarray for Sperm Surface Glycosylation Analysis Molecular & Cellular Proteomics : MCP. Sep, 2016 | Pubmed ID: 27364157 Uterine Expression of NDRG4 Is Induced by Estrogen and Up-Regulated During Embryo Implantation Process in Mice PloS One. 2016 | Pubmed ID: 27175791 The Association Between Calcium, Magnesium, and Ratio of Calcium/Magnesium in Seminal Plasma and Sperm Quality Biological Trace Element Research. Nov, 2016 | Pubmed ID: 27071612 Lectin Binding of Human Sperm Associates with DEFB126 Mutation and Serves As a Potential Biomarker for Subfertility Scientific Reports. Feb, 2016 | Pubmed ID: 26832966 Mutations in TUBB8 and Human Oocyte Meiotic Arrest The New England Journal of Medicine. Jan, 2016 | Pubmed ID: 26789871 The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes PloS One. 2015 | Pubmed ID: 26529315 Characterization of β-defensin 42 Expressed in Principal Cells at the Initial Segment of the Rat Epididymis Acta Biochimica Et Biophysica Sinica. Nov, 2015 | Pubmed ID: 26363282 Altered MicroRNAs Expression Profiling in Cumulus Cells from Patients with Polycystic Ovary Syndrome Journal of Translational Medicine. Jul, 2015 | Pubmed ID: 26198660 Alteration of Sperm Protein Profile Induced by Cigarette Smoking Acta Biochimica Et Biophysica Sinica. Jul, 2015 | Pubmed ID: 26063603 MiRNA-320 in the Human Follicular Fluid is Associated with Embryo Quality in Vivo and Affects Mouse Embryonic Development in Vitro Scientific Reports. Mar, 2015 | Pubmed ID: 25732513 Another Functional Frame-shift Polymorphism of DEFB126 (rs11467497) Associated with Male Infertility Journal of Cellular and Molecular Medicine. May, 2015 | Pubmed ID: 25721098 Acetylproteomic Analysis Reveals Functional Implications of Lysine Acetylation in Human Spermatozoa (sperm) Molecular & Cellular Proteomics : MCP. Apr, 2015 | Pubmed ID: 25680958 The Ser680Asn Polymorphism in the Follicle-stimulating Hormone Receptor Gene is Associated with the Ovarian Response in Controlled Ovarian Hyperstimulation Clinical Endocrinology. Apr, 2015 | Pubmed ID: 25132286 Meta-analyses of 4 CFTR Variants Associated with the Risk of the Congenital Bilateral Absence of the Vas Deferens Journal of Clinical Bioinformatics. 2014 | Pubmed ID: 25170420 CDNA Cloning and Localization of Sp3111 (also Called Ms4a14) in the Rat Testis Reproduction (Cambridge, England). Jul, 2014 | Pubmed ID: 24694585 Comprehensive Profiling of Accessible Surface Glycans of Mammalian Sperm Using a Lectin Microarray Clinical Proteomics. Mar, 2014 | Pubmed ID: 24629138 Reproductive Effects of Two Neonicotinoid Insecticides on Mouse Sperm Function and Early Embryonic Development in Vitro PloS One. 2013 | Pubmed ID: 23922925 The Effects of Di-(2-ethylhexyl)-phthalate Exposure on Fertilization and Embryonic Development in Vitro and Testicular Genomic Mutation in Vivo PloS One. 2012 | Pubmed ID: 23226291 Does Prohibitin Expression Regulate Sperm Mitochondrial Membrane Potential, Sperm Motility, and Male Fertility? Antioxidants & Redox Signaling. Aug, 2012 | Pubmed ID: 22324369 Does High Load of Oxidants in Human Semen Contribute to Male Factor Infertility? Antioxidants & Redox Signaling. Apr, 2012 | Pubmed ID: 22149455 A Sperm Viability Test Using SYBR-14/propidium Iodide Flow Cytometry As a Tool for Rapid Screening of Primary Ciliary Dyskinesia Patients and for Choosing Sperm Sources for Intracytoplasmic Sperm Injection Fertility and Sterility. Jan, 2011 | Pubmed ID: 20797703 [Impact of Cigarette Smoking on Human Sperm DNA Integrity] Zhonghua Nan Ke Xue = National Journal of Andrology. Apr, 2010 | Pubmed ID: 20626155 Generation of Sp3111 Transgenic RNAi Mice Via Permanent Integration of Small Hairpin RNAs in Repopulating Spermatogonial Cells in VivoGeneration of Sp3111 Transgenic RNAi Mice Via Permanent Integration of Small Hairpin RNAs in Repopulating Spermatogonial Cells in Vivo Acta Biochimica Et Biophysica Sinica. Feb, 2010 | Pubmed ID: 20119622 [Updated Reproductive Function of Human Sperm RNA] Zhonghua Nan Ke Xue = National Journal of Andrology. Mar, 2009 | Pubmed ID: 19452700 Effect of Traditional Chinese Herbs Combined with Low Dose Human Menopausal Gonadotropin Applied in Frozen-thawed Embryo Transfer Chinese Journal of Integrative Medicine. Dec, 2006 | Pubmed ID: 17361518 Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions Xuemei Wang1, Yisi Sun1, Huijuan Shi1,2, Aijie Xin1,2 1Shanghai-MOST Key Laboratory of Health and Disease Genomics, NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), School of Pharmacy, Fudan University, 2Affiliated Hospital of Youjiang Medical University for Nationalities JoVE 66873 생물학 Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring Jianan Tang1,2,3, Baoli Zhang1,2,3, Chunhua Tang4,5,6, Xuemei Wang1,2,3, Minmin Hua1,2,3, Yuchuan Zhou4,5,6, Huijuan Shi1,2,3, Tiancheng Zhang1,2,3 1Shanghai-MOST Key Laboratory of Health and Disease Genomics, 2NHC Key Lab of Reproduction Regulation, 3Shanghai Institute for Biomedical and Pharmaceutical Technologies, 4International Peace Maternity and Child Health Hospital, 5School of Medicine, Shanghai Jiao Tong University, 6Shanghai Key Laboratory of Embryo Original Diseases JoVE 66212 발생학
Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions Xuemei Wang1, Yisi Sun1, Huijuan Shi1,2, Aijie Xin1,2 1Shanghai-MOST Key Laboratory of Health and Disease Genomics, NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), School of Pharmacy, Fudan University, 2Affiliated Hospital of Youjiang Medical University for Nationalities JoVE 66873 생물학
Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring Jianan Tang1,2,3, Baoli Zhang1,2,3, Chunhua Tang4,5,6, Xuemei Wang1,2,3, Minmin Hua1,2,3, Yuchuan Zhou4,5,6, Huijuan Shi1,2,3, Tiancheng Zhang1,2,3 1Shanghai-MOST Key Laboratory of Health and Disease Genomics, 2NHC Key Lab of Reproduction Regulation, 3Shanghai Institute for Biomedical and Pharmaceutical Technologies, 4International Peace Maternity and Child Health Hospital, 5School of Medicine, Shanghai Jiao Tong University, 6Shanghai Key Laboratory of Embryo Original Diseases JoVE 66212 발생학