Irina V. Kovtun Center for Individualized Medicine Mayo Clinic Biography Publications Institution JoVE Articles Irina V. Kovtun has not added a biography. If you are Irina V. Kovtun and would like to personalize this page please email our Author Liaison for assistance. Publications Large Chromosomal Rearrangements Yield Biomarkers to Distinguish Low-Risk From Intermediate- and High-Risk Prostate Cancer Mayo Clinic Proceedings. 01, 2019 | Pubmed ID: 30611450 Targeting HER2 in Patient-derived Xenograft Ovarian Cancer Models Sensitizes Tumors to Chemotherapy Molecular Oncology. 02, 2019 | Pubmed ID: 30499260 Frequently Rearranged and Overexpressed δ-catenin is Responsible for Low Sensitivity of Prostate Cancer Cells to Androgen Receptor and β-catenin Antagonists Oncotarget. May, 2018 | Pubmed ID: 29849951 EGFR Mediates Activation of RET in Lung Adenocarcinoma with Neuroendocrine Differentiation Characterized by ASCL1 Expression Oncotarget. Apr, 2017 | Pubmed ID: 28460442 Quantification of Somatic Chromosomal Rearrangements in Circulating Cell-Free DNA from Ovarian Cancers Scientific Reports. 07, 2016 | Pubmed ID: 27436510 Topoisomerase 2 Alpha Cooperates with Androgen Receptor to Contribute to Prostate Cancer Progression PloS One. 2015 | Pubmed ID: 26560244 Chromosomal Catastrophe is a Frequent Event in Clinically Insignificant Prostate Cancer Oncotarget. Oct, 2015 | Pubmed ID: 26337081 Lineage Relationship of Gleason Patterns in Gleason Score 7 Prostate Cancer Cancer Research. Jun, 2013 | Pubmed ID: 23695551 Genome-wide Analysis Reveals Recurrent Structural Abnormalities of TP63 and Other P53-related Genes in Peripheral T-cell Lymphomas Blood. Sep, 2012 | Pubmed ID: 22855598 Cockayne Syndrome B Protein Antagonizes OGG1 in Modulating CAG Repeat Length in Vivo Aging. May, 2011 | Pubmed ID: 21566259 Increased Incidence of Endometrioid Tumors Caused by Aberrations in E-cadherin Promoter of Mismatch Repair-deficient Mice Carcinogenesis. Jul, 2011 | Pubmed ID: 21551128 A Survey of Patient Advocates Within the National Cancer Institute's Prostate Cancer SPORE Program: Who Are They? What Motivates Them? What Might They Tell Us? Journal of Cancer Education : the Official Journal of the American Association for Cancer Education. 2008 | Pubmed ID: 19058069 Gene Panel Model Predictive of Outcome in Men at High-risk of Systemic Progression and Death from Prostate Cancer After Radical Retropubic Prostatectomy Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2008 | Pubmed ID: 18711181 Features of Trinucleotide Repeat Instability in Vivo Cell Research. Jan, 2008 | Pubmed ID: 18166978 OGG1 Initiates Age-dependent CAG Trinucleotide Expansion in Somatic Cells Nature. May, 2007 | Pubmed ID: 17450122 Crosstalk of DNA Glycosylases with Pathways Other Than Base Excision Repair DNA Repair. Apr, 2007 | Pubmed ID: 17129768 Triplet Repeats and DNA Repair: Germ Cell and Somatic Cell Instability in Transgenic Mice Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 15201465 CAG Repeat Lengths in X- and Y-bearing Sperm Indicate That Gender Bias During Transmission of Huntington's Disease Gene is Determined in the Embryo The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14688268 Microtubule Destabilization and Nuclear Entry Are Sequential Steps Leading to Toxicity in Huntington's Disease Proceedings of the National Academy of Sciences of the United States of America. Oct, 2003 | Pubmed ID: 14527999 Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts Piyan Zhang1, Irina V. Kovtun1,2 1Center for Individualized Medicine, Mayo Clinic, 2Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic JoVE 60646 암 연구학
Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts Piyan Zhang1, Irina V. Kovtun1,2 1Center for Individualized Medicine, Mayo Clinic, 2Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic JoVE 60646 암 연구학