Jürgen Hescheler Institute of Neurophysiology, Faculty of Medicine University of Cologne Biography Publications Institution JoVE Articles Jürgen Hescheler has not added a biography. If you are Jürgen Hescheler and would like to personalize this page please email our Author Liaison for assistance. Publications In Vitro Grown Micro-Tissues for Cardiac Cell Replacement Therapy in Vivo Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2019 | Pubmed ID: 31050280 Ca3.2 T-Type Calcium Channels Are Physiologically Mandatory for the Auditory System Neuroscience. Apr, 2019 | Pubmed ID: 31029730 Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes Cells. Apr, 2019 | Pubmed ID: 31013958 Docosahexaenoic Acid Alters Gsα Localization in Lipid Raft and Potentiates Adenylate Cyclase Nutrition (Burbank, Los Angeles County, Calif.). Jul-Aug, 2015 | Pubmed ID: 26059378 Calcium Imaging in Pluripotent Stem Cell-Derived Cardiac Myocytes Methods in Molecular Biology (Clifton, N.J.). May, 2015 | Pubmed ID: 26025623 Ascorbic Acid-Induced Cardiac Differentiation of Murine Pluripotent Stem Cells: Transcriptional Profiling and Effect of a Small Molecule Synergist of Wnt/β-Catenin Signaling Pathway Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2015 | Pubmed ID: 26021268 Effects of Synthetic Neural Adhesion Molecule Mimetic Peptides and Related Proteins on the Cardiomyogenic Differentiation of Mouse Embryonic Stem Cells Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2015 | Pubmed ID: 25967873 Chromosome Tracking in Fused Cells by Single Nucleotide Polymorphisms Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25947658 Excitation-contraction Coupling in Zebrafish Ventricular Myocardium is Regulated by Trans-sarcolemmal Ca2+ Influx and Sarcoplasmic Reticulum Ca2+ Release PloS One. 2015 | Pubmed ID: 25938412 Susceptibility of Murine Induced Pluripotent Stem Cell-derived Cardiomyocytes to Hypoxia and Nutrient Deprivation Stem Cell Research & Therapy. 2015 | Pubmed ID: 25900017 Traditional Chinese Medicine Baicalin Suppresses MESCs Proliferation Through Inhibition of MiR-294 Expression Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2015 | Pubmed ID: 25871338 Voltage-gated Calcium Channels: Determinants of Channel Function and Modulation by Inorganic Cations Progress in Neurobiology. Jun, 2015 | Pubmed ID: 25817891 Regionally Diverse Mitochondrial Calcium Signaling Regulates Spontaneous Pacing in Developing Cardiomyocytes Cell Calcium. May, 2015 | Pubmed ID: 25746147 Stem Cells and Differentiation - a Synoptic Review of Patents Granted Since 2009 Expert Opinion on Therapeutic Patents. Jun, 2015 | Pubmed ID: 25732569 In Vitro Chronotropic Effects of Erythrina Senegalensis DC (Fabaceae) Aqueous Extract on Mouse Heart Slice and Pluripotent Stem Cell-derived Cardiomyocytes Journal of Ethnopharmacology. May, 2015 | Pubmed ID: 25680843 Stem Cell-derived Systems in Toxicology Assessment Stem Cells and Development. Jun, 2015 | Pubmed ID: 25675366 Signaling Molecules, Transcription Growth Factors and Other Regulators Revealed from In-vivo and In-vitro Models for the Regulation of Cardiac Development International Journal of Cardiology. Mar, 2015 | Pubmed ID: 25662074 Diethyldithiocarbamate-mediated Zinc Ion Chelation Reveals Role of Cav2.3 Channels in Glucagon Secretion Biochimica Et Biophysica Acta. May, 2015 | Pubmed ID: 25603538 Electrophysiological Characteristics of Embryonic Stem Cell-derived Cardiomyocytes Are Cell Line-dependent Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2015 | Pubmed ID: 25591772 DiXa: a Data Infrastructure for Chemical Safety Assessment Bioinformatics (Oxford, England). May, 2015 | Pubmed ID: 25505093 Preconditioning of Skeletal Myoblast-based Engineered Tissue Constructs Enables Functional Coupling to Myocardium In vivo The Journal of Thoracic and Cardiovascular Surgery. Jan, 2015 | Pubmed ID: 25439779 The SEURAT-1 Approach Towards Animal Free Human Safety Assessment ALTEX. 2015 | Pubmed ID: 25372315 Electrophysiological and Morphological Maturation of Murine Fetal Cardiomyocytes During Electrical Stimulation in Vitro Journal of Cardiovascular Pharmacology and Therapeutics. Jan, 2015 | Pubmed ID: 24917562 Optimized Generation of Functional Neutrophils and Macrophages from Patient-Specific Induced Pluripotent Stem Cells: Ex Vivo Models of X(0)-Linked, AR22(0)- and AR47(0)- Chronic Granulomatous Diseases BioResearch Open Access. Dec, 2014 | Pubmed ID: 25469316 Toxicogenomics Directory of Chemically Exposed Human Hepatocytes Archives of Toxicology. Dec, 2014 | Pubmed ID: 25399406 Cardiac Functions of Voltage-gated Ca(2+) Channels: Role of the Pharmacoresistant Type (E-/R-Type) in Cardiac Modulation and Putative Implication in Sudden Unexpected Death in Epilepsy (SUDEP) Reviews of Physiology, Biochemistry and Pharmacology. 2014 | Pubmed ID: 25280639 Functional Expression and Regulation of Hyperpolarization-activated Cyclic Nucleotide-gated Channels (HCN) in Mouse IPS Cell-derived Cardiomyocytes After UTF1 -neo Selection Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2014 | Pubmed ID: 25277677 Impurity of Stem Cell Graft by Murine Embryonic Fibroblasts - Implications for Cell-based Therapy of the Central Nervous System Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 25249934 Bioluminescent Imaging of Genetically Selected Induced Pluripotent Stem Cell-derived Cardiomyocytes After Transplantation into Infarcted Heart of Syngeneic Recipients PloS One. 2014 | Pubmed ID: 25226590 A Comparative Transcriptomic Study on the Effects of Valproic Acid on Two Different HESCs Lines in a Neural Teratogenicity Test System Toxicology Letters. Nov, 2014 | Pubmed ID: 25192806 The Proliferative and Chronotropic Effects of Brillantaisia Nitens Lindau (Acanthaceae) Extracts on Pluripotent Stem Cells and Their Cardiomyocytes Derivatives Journal of Ethnopharmacology. Oct, 2014 | Pubmed ID: 25086409 Puerarin Facilitates T-tubule Development of Murine Embryonic Stem Cell-derived Cardiomyocytes Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2014 | Pubmed ID: 25059232 Combining Hypoxia and Bioreactor Hydrodynamics Boosts Induced Pluripotent Stem Cell Differentiation Towards Cardiomyocytes Stem Cell Reviews. Dec, 2014 | Pubmed ID: 25022569 ESNATS Conference - the Use of Human Embryonic Stem Cells for Novel Toxicity Testing Approaches Alternatives to Laboratory Animals : ATLA. May, 2014 | Pubmed ID: 24901904 The Influence of Physiological Matrix Conditions on Permanent Culture of Induced Pluripotent Stem Cell-derived Cardiomyocytes Biomaterials. Aug, 2014 | Pubmed ID: 24889032 Unique Metabolic Features of Stem Cells, Cardiomyocytes, and Their Progenitors Circulation Research. Apr, 2014 | Pubmed ID: 24723659 Cardiac Phenomena During Kainic-acid Induced Epilepsy and Lamotrigine Antiepileptic Therapy Epilepsy Research. May, 2014 | Pubmed ID: 24642265 Gadolinium Enhancement in Newly Diagnosed Patients with Lumbar Disc Herniations Are Associated with Inflammatory Peridiscal Tissue Reactions--evidence of Fragment Degradation? Clinical Neurology and Neurosurgery. Apr, 2014 | Pubmed ID: 24635921 Modulation of L-type Calcium Current by Intracellular Magnesium in Differentiating Cardiomyocytes Derived from Induced Pluripotent Stem Cells Stem Cells and Development. Jun, 2014 | Pubmed ID: 24527794 Cell Persistence and Electrical Integration of Transplanted Fetal Cardiomyocytes from Different Developmental Stages International Journal of Cardiology. Feb, 2014 | Pubmed ID: 24439862 Design Principles of Concentration-dependent Transcriptome Deviations in Drug-exposed Differentiating Stem Cells Chemical Research in Toxicology. Mar, 2014 | Pubmed ID: 24383497 Evidence for Self-maintaining Pluripotent Murine Stem Cells in Embryoid Bodies Stem Cell Reviews. Feb, 2014 | Pubmed ID: 24022811 The Disease-specific Phenotype in Cardiomyocytes Derived from Induced Pluripotent Stem Cells of Two Long QT Syndrome Type 3 Patients PloS One. 2013 | Pubmed ID: 24349418 How "Pharmacoresistant" is Cav2.3, the Major Component of Voltage-Gated R-type Ca2+ Channels? Pharmaceuticals (Basel, Switzerland). 2013 | Pubmed ID: 24276260 Test Systems of Developmental Toxicity: State-of-the Art and Future Perspectives Archives of Toxicology. Dec, 2013 | Pubmed ID: 24190503 Effects of Puerarin on Cardiac Differentiation and Ventricular Specialization of Murine Embryonic Stem Cells Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. Sep, 2013 | Pubmed ID: 24080853 Electrophysiological Integration and Action Potential Properties of Transplanted Cardiomyocytes Derived from Induced Pluripotent Stem Cells Cardiovascular Research. Dec, 2013 | Pubmed ID: 24042016 Evidence for a Critical Role of Catecholamines for Cardiomyocyte Lineage Commitment in Murine Embryonic Stem Cells PloS One. 2013 | Pubmed ID: 23936474 Coculture of Embryonic Ventricular Myocytes and Mouse Embryonic Stem Cell Enhance Intercellular Signaling by Upregulation of Connexin43 Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2013 | Pubmed ID: 23867886 A New Model to Perform Electrophysiological Studies in the Early Embryonic Mouse Heart Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2013 | Pubmed ID: 23867719 Baicalin Maintains Late-stage Functional Cardiomyocytes in Embryoid Bodies Derived from Murine Embryonic Stem Cells Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2013 | Pubmed ID: 23839251 Cav 2.3 (R-type) Calcium Channels Are Critical for Mediating Anticonvulsive and Neuroprotective Properties of Lamotrigine in Vivo Epilepsia. Sep, 2013 | Pubmed ID: 23772876 Intracerebral Administration of Heat-inactivated Staphylococcus Epidermidis Enhances Oncolysis and Prolongs Survival in a 9L Orthotopic Gliosarcoma Model Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2013 | Pubmed ID: 23652608 Reconsidering Pluripotency Tests: Do We Still Need Teratoma Assays? Stem Cell Research. Jul, 2013 | Pubmed ID: 23611953 Pitfalls and Fallacies Interfering with Correct Identification of Embryonic Stem Cells Implanted into the Brain After Experimental Traumatic Injury Journal of Neuroscience Methods. Apr, 2013 | Pubmed ID: 23454685 The L-type Ca2+ Channels Blocker Nifedipine Represses Mesodermal Fate Determination in Murine Embryonic Stem Cells PloS One. 2013 | Pubmed ID: 23320083 All-trans Retinoic Acid and Basic Fibroblast Growth Factor Synergistically Direct Pluripotent Human Embryonic Stem Cells to Extraembryonic Lineages Stem Cell Research. Mar, 2013 | Pubmed ID: 23314291 Effect of High-intensity Irradiation from Dental Photopolymerization on the Isolated and Superfused Vertebrate Retina Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Mar, 2013 | Pubmed ID: 23263622 Impacto De Autoanticuerpos Humanos Sobre La Conformación De Los Receptores Adrenérgicos β1, Actividad E Internalización Cardiovascular Research. Mar, 2013 | Pubmed ID: 23208588 Human Embryonic Stem Cell-derived Test Systems for Developmental Neurotoxicity: a Transcriptomics Approach Archives of Toxicology. Jan, 2013 | Pubmed ID: 23179753 Pharmacoresistant Cav 2·3 (E-type/R-type) Voltage-gated Calcium Channels Influence Heart Rate Dynamics and May Contribute to Cardiac Impulse Conduction Cell Biochemistry and Function. Jul, 2013 | Pubmed ID: 23086800 Induced Pluripotent Mesenchymal Stromal Cell Clones Retain Donor-derived Differences in DNA Methylation Profiles Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2013 | Pubmed ID: 23032973 First Steps Towards the Successful Surface-based Cultivation of Human Embryonic Stem Cells in Hanging Drop Systems Engineering in Life Sciences. Nov, 2012 | Pubmed ID: 23486530 Human Pluripotent Stem Cell-derived Cardiomyocytes: Response to TTX and Lidocain Reveals Strong Cell to Cell Variability PloS One. 2012 | Pubmed ID: 23029342 Differentiation and Selection of Hepatocyte Precursors in Suspension Spheroid Culture of Transgenic Murine Embryonic Stem Cells PloS One. 2012 | Pubmed ID: 23028675 Identification of Thalidomide-specific Transcriptomics and Proteomics Signatures During Differentiation of Human Embryonic Stem Cells PloS One. 2012 | Pubmed ID: 22952932 Epigenetic Changes and Disturbed Neural Development in a Human Embryonic Stem Cell-based Model Relating to the Fetal Valproate Syndrome Human Molecular Genetics. Sep, 2012 | Pubmed ID: 22723015 The C-terminus of Human Ca(v)2.3 Voltage-gated Calcium Channel Interacts with Alternatively Spliced Calmodulin-2 Expressed in Two Human Cell Lines Biochimica Et Biophysica Acta. Sep, 2012 | Pubmed ID: 22633975 Spironolactone Prevents Aldosterone Induced Increased Duration of Atrial Fibrillation in Rat Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2012 | Pubmed ID: 22613983 In Vitro Model for Assessing Arrhythmogenic Properties of Drugs Based on High-resolution Impedance Measurements Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2012 | Pubmed ID: 22613982 Cellular Response on Auger- and Beta-emitting Nuclides: Human Embryonic Stem Cells (hESC) Vs. Keratinocytes International Journal of Radiation Biology. Dec, 2012 | Pubmed ID: 22494164 Firmas De Expresión Génica Definir Procesos Biológicos Fundamentales En Pluripotentes, Temprana Y Tardía Distinguen Las Células Madre Embrionarias Stem Cells and Development. Sep, 2012 | Pubmed ID: 22420508 Properties and Functions of KATP During Mouse Perinatal Development Biochemical and Biophysical Research Communications. Feb, 2012 | Pubmed ID: 22252295 Organotypic Slice Culture from Human Adult Ventricular Myocardium Cardiovascular Research. Jan, 2012 | Pubmed ID: 21972180 Functional Characterization and Gene Expression Profiling of α-smooth Muscle Actin Expressing Cardiomyocytes Derived from Murine Induced Pluripotent Stem Cells Stem Cell Reviews. Mar, 2012 | Pubmed ID: 21567216 Firmas De Gen Específico Y Vías En Células Mesodérmicas Y Sus Derivados Derivan De Células Madre Embrionarias Stem Cell Reviews. Mar, 2012 | Pubmed ID: 21519850 APLP1 and Rab5A Interact with the II-III Loop of the Voltage-gated Ca-channel Ca(v)2.3 and Modulate Its Internalization Differently Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2011 | Pubmed ID: 22178872 Development of a Neural Teratogenicity Test Based on Human Embryonic Stem Cells: Response to Retinoic Acid Exposure Toxicological Sciences : an Official Journal of the Society of Toxicology. Dec, 2011 | Pubmed ID: 21934132 Two Separate Ni(2+) -sensitive Voltage-gated Ca(2+) Channels Modulate Transretinal Signalling in the Isolated Murine Retina Acta Ophthalmologica. Nov, 2011 | Pubmed ID: 21883984 Integration Properties of Wharton's Jelly-derived Novel Mesenchymal Stem Cells into Ventricular Slices of Murine Hearts Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2011 | Pubmed ID: 21865849 Adenylyl Cyclase/cAMP-PKA-mediated Phosphorylation of Basal L-type Ca(2+) Channels in Mouse Embryonic Ventricular Myocytes Cell Calcium. Nov, 2011 | Pubmed ID: 21824653 Molecular and Functional Changes in Voltage-gated Na⁺ Channels in Cardiomyocytes During Mouse Embryogenesis Circulation Journal : Official Journal of the Japanese Circulation Society. 2011 | Pubmed ID: 21712609 Ca(v)2.3 Ca2+ Channel Interacts with the G1-subunit of V-ATPase Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2011 | Pubmed ID: 21691059 Imaging Herpes Simplex Virus Type 1 Amplicon Vector-mediated Gene Expression in Human Glioma Spheroids Molecular Imaging. Jun, 2011 | Pubmed ID: 21443839 Concise Review: Induced Pluripotent Stem Cells and Lineage Reprogramming: Prospects for Bone Regeneration Stem Cells (Dayton, Ohio). Apr, 2011 | Pubmed ID: 21308867 Effects of Cryopreservation on the Transcriptome of Human Embryonic Stem Cells After Thawing and Culturing Stem Cell Reviews. Sep, 2011 | Pubmed ID: 21279480 Biological and Physicochemical Characterization of a Serum- and Xeno-free Chemically Defined Cryopreservation Procedure for Adult Human Progenitor Cells Cell Transplantation. 2011 | Pubmed ID: 21176408 Direct Differentiation of Atrial and Ventricular Myocytes from Human Embryonic Stem Cells by Alternating Retinoid Signals Cell Research. Apr, 2011 | Pubmed ID: 21102549 Direct Contact of Umbilical Cord Blood Endothelial Progenitors with Living Cardiac Tissue is a Requirement for Vascular Tube-like Structures Formation Journal of Cellular and Molecular Medicine. Sep, 2011 | Pubmed ID: 21029374 Extract Derived from Rat Brains in the Acute Phase Following Traumatic Brain Injury Impairs Survival of Undifferentiated Stem Cells and Induces Rapid Differentiation of Surviving Cells Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2010 | Pubmed ID: 21220913 Hyposmotic Challenge Modulates Function of L-type Calcium Channel in Rat Ventricular Myocytes Through Protein Kinase C Acta Pharmacologica Sinica. Nov, 2010 | Pubmed ID: 20953210 Global Transcriptional Profiles of Beating Clusters Derived from Human Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Highly Similar BMC Developmental Biology. 2010 | Pubmed ID: 20843318 Functional Characterization of Inward Rectifier Potassium Ion Channel in Murine Fetal Ventricular Cardiomyocytes Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2010 | Pubmed ID: 20798526 Induced Pluripotent Stem Cells: a New Approach for Physiological Research Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2010 | Pubmed ID: 20798495 Analyzing Murine Electrocardiogram with PhysioToolkit Journal of Electrocardiology. Nov-Dec, 2010 | Pubmed ID: 20638669 Aislamiento Y Caracterización Funcional De La Actina Del Músculo Liso-alfa Expresando Cardiomiocitos De Células Madre Embrionarias Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2010 | Pubmed ID: 20511704 Electrophysiological Basis of the First Heart Beats Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2010 | Pubmed ID: 20511701 From Dolly to HiPS: New Insights into Reprogramming Cell Cycle (Georgetown, Tex.). Apr, 2010 | Pubmed ID: 20404531 WITHDRAWN: Capsaicin Inhibits Beta-adrenergically-activated Na(+) Current Through Endogenous Calcineurin in Cardiac Myocytes Biochemical and Biophysical Research Communications. Apr, 2010 | Pubmed ID: 20398627 Markers of Murine Embryonic and Neural Stem Cells, Neurons and Astrocytes: Reference Points for Developmental Neurotoxicity Testing ALTEX. 2010 | Pubmed ID: 20390237 Comparison of Contractile Behavior of Native Murine Ventricular Tissue and Cardiomyocytes Derived from Embryonic or Induced Pluripotent Stem Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2010 | Pubmed ID: 20371616 A Cre-based Double Fluorescence Indicator System for Monitoring Cell Fusion Events and Selection of Fused Cells BioTechniques. Feb, 2010 | Pubmed ID: 20359294 Human and Murine Embryonic Stem Cell-derived Cardiomyocytes Serve Together As a Valuable Model for Drug Safety Screening Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2010 | Pubmed ID: 20332627 Initial Colony Morphology-based Selection for IPS Cells Derived from Adult Fibroblasts is Substantially Improved by Temporary UTF1-based Selection PloS One. 2010 | Pubmed ID: 20221450 Análisis Transcriptómico Global De Células Murinas Brachyury Derivadas De Células Madre Embrionarias (T) Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Feb, 2010 | Pubmed ID: 20184659 Fibroblasts Facilitate the Engraftment of Embryonic Stem Cell-derived Cardiomyocytes on Three-dimensional Collagen Matrices and Aggregation in Hanging Drops Stem Cells and Development. Oct, 2010 | Pubmed ID: 20175666 Heat Shock Proteins and Ion Channels. Functional Interactions and Therapeutic Consequences Current Pharmaceutical Biotechnology. Feb, 2010 | Pubmed ID: 20166964 Atrial Natriuretic Peptide Regulates Ca Channel in Early Developmental Cardiomyocytes PloS One. 2010 | Pubmed ID: 20107504 Chemically Induced Cardiomyogenesis of Mouse Embryonic Stem Cells Chembiochem : a European Journal of Chemical Biology. Jan, 2010 | Pubmed ID: 20039251 Antagonists of Ionotropic Gamma-aminobutyric Acid Receptors Impair the NiCl2-mediated Stimulation of the Electroretinogram B-wave Amplitude from the Isolated Superfused Vertebrate Retina Acta Ophthalmologica. Nov, 2009 | Pubmed ID: 20002018 El FunGenES Base De Datos: Un Recurso De Genómica Para La Diferenciación De Embriones De Ratón Con Células Madre PloS One. 2009 | Pubmed ID: 19727443 Functional Coupling Between MGluR1 and Cav3.1 T-type Calcium Channels Contributes to Parallel Fiber-induced Fast Calcium Signaling Within Purkinje Cell Dendritic Spines The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2009 | Pubmed ID: 19657020 Developmental Potential of the Murine Embryonic Stem Cells Transplanted into the Healthy Rat Brain--novel Insights into Tumorigenesis Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2009 | Pubmed ID: 19590196 ¿La Proteína Del Grupo De Alta Movilidad HMGA2: Un Co-regulator De La Estructura De La Cromatina Y La Pluripotencia De Células Madre? Stem Cell Reviews. Sep, 2009 | Pubmed ID: 19551524 Somitovasculin, a Novel Endothelial-specific Transcript Involved in the Vasculature Development Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2009 | Pubmed ID: 19542019 Influence of Cell Treatment with PDGF-BB and Reperfusion on Cardiac Persistence of Mononuclear and Mesenchymal Bone Marrow Cells After Transplantation into Acute Myocardial Infarction in Rats Cell Transplantation. 2009 | Pubmed ID: 19520046 Chemoprotective Mechanism of the Natural Compounds, Epigallocatechin-3-O-gallate, Quercetin and Curcumin Against Cancer and Cardiovascular Diseases Current Medicinal Chemistry. 2009 | Pubmed ID: 19355899 Tres LIF Dependientes De Firmas Y Grupos De Genes Con Perfiles De Expresión Atípicos, Identificados Por Estudios De Transcriptoma En Células Madre Embrionarias De Ratón Y Derivados Primeros BMC Genomics. 2009 | Pubmed ID: 19203379 Transcriptional Profiling of CD31(+) Cells Isolated from Murine Embryonic Stem Cells Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Feb, 2009 | Pubmed ID: 19170770 Zonisamide Block of Cloned Human T-type Voltage-gated Calcium Channels Epilepsy Research. Feb, 2009 | Pubmed ID: 19124225 Análisis Funcional De La Caracterización Y El Transcriptoma De Células Musculares Lisas Contráctil Derivadas De Células Madre Embrionarias Hypertension. Feb, 2009 | Pubmed ID: 19064816 Role of Natural-killer Group 2 Member D Ligands and Intercellular Adhesion Molecule 1 in Natural Killer Cell-mediated Lysis of Murine Embryonic Stem Cells and Embryonic Stem Cell-derived Cardiomyocytes Stem Cells (Dayton, Ohio). Feb, 2009 | Pubmed ID: 18988711 Modulation of L-type Ca(2+) Channel Current Density and Inactivation by Beta-adrenergic Stimulation During Murine Cardiac Embryogenesis Basic Research in Cardiology. May, 2009 | Pubmed ID: 18953481 ES Humanos Cardiomiocitos Derivados Para La Terapia De Reemplazo De La Célula De La Célula: Una Actualización Actual The Chinese Journal of Physiology. Aug, 2008 | Pubmed ID: 19112880 Atrapamiento De Cardiomiocitos Derivadas De Células Madre Embrionarios En Microesferas Biodegradables Macroporoso: Preparación Y Caracterización Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2008 | Pubmed ID: 19088448 "The Good into the Pot, the Bad into the Crop!"--a New Technology to Free Stem Cells from Feeder Cells PloS One. 2008 | Pubmed ID: 19023443 Generation of Pluripotent Stem Cells from Adult Human Testis Nature. Nov, 2008 | Pubmed ID: 18849962 Altered Thalamocortical Rhythmicity in Ca(v)2.3-deficient Mice Molecular and Cellular Neurosciences. Dec, 2008 | Pubmed ID: 18834942 Generación De Un Vector De Indicador Fluorescente Doble Doble-seleccionable Cre/loxP Para Supervisión De Eventos De Recombinación Intracelular Nature Protocols. 2008 | Pubmed ID: 18772879 The Dihydropyridine Isradipine Inhibits the Murine but Not the Bovine A-wave Response of the Electroretinogram Acta Ophthalmologica. Sep, 2008 | Pubmed ID: 18752519 Perlecan is Critical for Heart Stability Cardiovascular Research. Dec, 2008 | Pubmed ID: 18694874 The WNT Receptor FZD7 Contributes to Self-renewal Signaling of Human Embryonic Stem Cells Biological Chemistry. Jul, 2008 | Pubmed ID: 18681827 Scalable Selection of Hepatocyte- and Hepatocyte Precursor-like Cells from Culture of Differentiating Transgenically Modified Murine Embryonic Stem Cells Stem Cells (Dayton, Ohio). Sep, 2008 | Pubmed ID: 18556507 Immunological Barriers to Embryonic Stem Cell-derived Therapies Cells, Tissues, Organs. 2008 | Pubmed ID: 18303241 A Chemical Genetics Approach for Specific Differentiation of Stem Cells to Somatic Cells: a New Promising Therapeutical Approach Combinatorial Chemistry & High Throughput Screening. Jan, 2008 | Pubmed ID: 18220544 Phosphatidylinositol 3-kinase-dependent Membrane Recruitment of Rac-1 and P47phox is Critical for Alpha-platelet-derived Growth Factor Receptor-induced Production of Reactive Oxygen Species The Journal of Biological Chemistry. Mar, 2008 | Pubmed ID: 18070887 Direct Current Electrical Fields Induce Apoptosis in Oral Mucosa Cancer Cells by NADPH Oxidase-derived Reactive Oxygen Species Bioelectromagnetics. Jan, 2008 | Pubmed ID: 17786977 [Decrease of Extracellular PH Modulates the Whole Cell Voltage-gated Potassium Currents in Rat Pulmonary Artery Smooth Muscle Cells] Zhongguo Ying Yong Sheng Li Xue Za Zhi = Zhongguo Yingyong Shenglixue Zazhi = Chinese Journal of Applied Physiology. May, 2007 | Pubmed ID: 21179759 Fusion and Regenerative Therapies: is Immortality Really Recessive? Rejuvenation Research. Dec, 2007 | Pubmed ID: 18072882 Epigallocatechin-3-O-gallate Inhibits the Angiotensin II-induced Adhesion Molecule Expression in Human Umbilical Vein Endothelial Cell Via Inhibition of MAPK Pathways Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2007 | Pubmed ID: 17982268 Transcriptómico Y Análisis Fenotípico De Murino Células Madre Embrionarias Derivan De Células De Linaje De BMP2 +: Una Visión De Patrones Mesodérmico Genome Biology. 2007 | Pubmed ID: 17784959 In Vitro Differentiation of Murine Embryonic Stem Cells into Keratinocyte-like Cells European Journal of Cell Biology. Dec, 2007 | Pubmed ID: 17716780 Effect of Cardioactive Drugs on Action Potential Generation and Propagation in Embryonic Stem Cell-derived Cardiomyocytes Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2007 | Pubmed ID: 17495462 Regulation of the Na+/Ca2+ Exchanger (NCX) in the Murine Embryonic Heart Cardiovascular Research. Jul, 2007 | Pubmed ID: 17462611 Regulation of Na+/Ca2+ Exchange Current in the Normal and Failing Heart Annals of the New York Academy of Sciences. Mar, 2007 | Pubmed ID: 17446476 NCX Current in the Murine Embryonic Heart: Development-dependent Regulation by Na+ Annals of the New York Academy of Sciences. Mar, 2007 | Pubmed ID: 17446455 Trauma-associated Inflammatory Response Impairs Embryonic Stem Cell Survival and Integration After Implantation into Injured Rat Brain Journal of Neurotrauma. Apr, 2007 | Pubmed ID: 17439346 Análisis De Transcriptoma Global De Cardiomiocitos Murinos De Derivados De Células Madre Embrionarios Genome Biology. 2007 | Pubmed ID: 17428332 Hippocampal Seizure Resistance and Reduced Neuronal Excitotoxicity in Mice Lacking the Cav2.3 E/R-type Voltage-gated Calcium Channel Journal of Neurophysiology. May, 2007 | Pubmed ID: 17376845 Serpin-6 Expression Protects Embryonic Stem Cells from Lysis by Antigen-specific CTL Journal of Immunology (Baltimore, Md. : 1950). Mar, 2007 | Pubmed ID: 17339433 Embryonic Stem Cells Produce Neurotrophins in Response to Cerebral Tissue Extract: Cell Line-dependent Differences Journal of Neuroscience Research. Apr, 2007 | Pubmed ID: 17335079 Embryonic Stem Cell Transplantation After Experimental Traumatic Brain Injury Dramatically Improves Neurological Outcome, but May Cause Tumors Journal of Neurotrauma. Jan, 2007 | Pubmed ID: 17263685 Identification of Differentially Expressed Genes Involved in the Formation of Multicellular Tumor Spheroids by HT-29 Colon Carcinoma Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2007 | Pubmed ID: 17164780 Functional Expression of the Na+/Ca2+ Exchanger in the Embryonic Mouse Heart Journal of Molecular and Cellular Cardiology. Jan, 2007 | Pubmed ID: 17157311 Force Measurements of Human Embryonic Stem Cell-derived Cardiomyocytes in an in Vitro Transplantation Model Stem Cells (Dayton, Ohio). Jan, 2007 | Pubmed ID: 16973834 Identification of Small Signalling Molecules Promoting Cardiac-specific Differentiation of Mouse Embryonic Stem Cells Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2006 | Pubmed ID: 17170517 Cardiovascular Genomics: a Current Overview of in Vivo and in Vitro Studies Stem Cell Reviews. 2006 | Pubmed ID: 17142888 The FunGenES Consortium: Functional Genomics in Engineered Embryonic Stem Cells Stem Cell Reviews. 2006 | Pubmed ID: 17142879 Effective Engraftment but Poor Mid-term Persistence of Mononuclear and Mesenchymal Bone Marrow Cells in Acute and Chronic Rat Myocardial Infarction Journal of Molecular and Cellular Cardiology. Nov, 2006 | Pubmed ID: 16973174 The Ca(v)2.3 Voltage-gated Calcium Channel in Epileptogenesis--shedding New Light on an Enigmatic Channel Neuroscience and Biobehavioral Reviews. 2006 | Pubmed ID: 16963121 Ventricular Slices of Adult Mouse Hearts--a New Multicellular in Vitro Model for Electrophysiological Studies Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2006 | Pubmed ID: 16914885 Confrontation Cultures of Embryonic Stem Cells with Multicellular Tumor Spheroids to Study Tumor-induced Angiogenesis Methods in Molecular Biology (Clifton, N.J.). 2006 | Pubmed ID: 16881524 Generation and Characterization of Cardiomyocytes Under Serum-free Conditions Methods in Molecular Biology (Clifton, N.J.). 2006 | Pubmed ID: 16846026 Dietary Small Molecules and Large-scale Gene Expression Studies: an Experimental Approach for Understanding Their Beneficial Effects on the Development of Malignant and Non-malignant Proliferative Diseases Current Medicinal Chemistry. 2006 | Pubmed ID: 16787199 Altered Seizure Susceptibility in Mice Lacking the Ca(v)2.3 E-type Ca2+ Channel Epilepsia. May, 2006 | Pubmed ID: 16686648 Endostatin Influences Endothelial Morphology Via the Activated ERK1/2-kinase Endothelial Morphology and Signal Transduction Microvascular Research. May, 2006 | Pubmed ID: 16650878 Stem Cells and Their Potential Relevance to Paediatric Cardiology Cardiology in the Young. Apr, 2006 | Pubmed ID: 16553971 The Molecular Chaperone Hsp70 Interacts with the Cytosolic II-III Loop of the Cav2.3 E-type Voltage-gated Ca2+ Channel Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2006 | Pubmed ID: 16543726 Generation and Characterization of Functional Cardiomyocytes from Rhesus Monkey Embryonic Stem Cells Stem Cells (Dayton, Ohio). Jun, 2006 | Pubmed ID: 16543489 Effect of Hypoxia on Hyperpolarization-activated Current in Mouse Dorsal Root Ganglion Neurons Brain Research. Mar, 2006 | Pubmed ID: 16494853 [Investigation on Spontaneous Electrical Activity of Murine Embryonic Heart Using Microelectrode Arrays] Sheng Li Xue Bao : [Acta Physiologica Sinica]. Feb, 2006 | Pubmed ID: 16489406 Action of Beta-amyloid Peptide₁₋₄₀ on I(HVA) and Its Modulation by Ginkgolide B Sheng Li Xue Bao : [Acta Physiologica Sinica]. Feb, 2006 | Pubmed ID: 16489398 The Isolated Perfused Bovine Retina--a Sensitive Tool for Pharmacological Research on Retinal Function Brain Research. Brain Research Protocols. Dec, 2005 | Pubmed ID: 16275053 An Optimized Embryonic Stem Cell Model for Consistent Gene Expression and Developmental Studies: a Fundamental Study Thrombosis and Haemostasis. Oct, 2005 | Pubmed ID: 16270623 S100A1 Enhances the L-type Ca2+ Current in Embryonic Mouse and Neonatal Rat Ventricular Cardiomyocytes The Journal of Biological Chemistry. Oct, 2005 | Pubmed ID: 16129693 Effects of Phosphodiesterase Type 5 Inhibitor Sildenafil on Retinal Function in Isolated Superfused Retina Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Aug, 2005 | Pubmed ID: 16117694 Reactive Oxygen Species-linked Regulation of the Multidrug Resistance Transporter P-glycoprotein in Nox-1 Overexpressing Prostate Tumor Spheroids FEBS Letters. Aug, 2005 | Pubmed ID: 16083877 Embryonic Stem Cells for Basic Research and Potential Clinical Applications in Cardiology Biochimica Et Biophysica Acta. May, 2005 | Pubmed ID: 15949691 Trapping of Growth Factors by Catechins: a Possible Therapeutical Target for Prevention of Proliferative Diseases The Journal of Nutritional Biochemistry. May, 2005 | Pubmed ID: 15866224 A Ni(2+)-sensitive Component of the ERG B-wave from the Isolated Bovine Retina is Related to E-type Voltage-gated Ca(2+) Channels Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Sep, 2005 | Pubmed ID: 15838665 [Extracellular Calcium Modulates the Whole Cell Potassium Currents in Deiters Cells Isolated from Guinea Pig Cochlea] Sheng Li Xue Bao : [Acta Physiologica Sinica]. Apr, 2005 | Pubmed ID: 15830108 Electrocorticographic and Deep Intracerebral EEG Recording in Mice Using a Telemetry System Brain Research. Brain Research Protocols. Apr, 2005 | Pubmed ID: 15795169 The Ablation of the Ca(v)2.3/E-type Voltage-gated Ca2+ Channel Causes a Mild Phenotype Despite an Altered Glucose Induced Glucagon Response in Isolated Islets of Langerhans European Journal of Pharmacology. Mar, 2005 | Pubmed ID: 15777780 Redox Control of Angiogenic Factors and CD31-positive Vessel-like Structures in Mouse Embryonic Stem Cells After Direct Current Electrical Field Stimulation Experimental Cell Research. Apr, 2005 | Pubmed ID: 15748885 Different Signal Molecules Involved in the Muscarinic Modulation of Pacemaker Current I(f) on the Heart of Mouse Embryo in Different Developmental Stages Sheng Li Xue Bao : [Acta Physiologica Sinica]. Feb, 2005 | Pubmed ID: 15719133 Ablation of Ca(v)2.3 / E-type Voltage-gated Calcium Channel Results in Cardiac Arrhythmia and Altered Autonomic Control Within the Murine Cardiovascular System Basic Research in Cardiology. Jan, 2005 | Pubmed ID: 15490203 Regulation of the Multidrug Resistance Transporter P-glycoprotein in Multicellular Prostate Tumor Spheroids by Hyperthermia and Reactive Oxygen Species International Journal of Cancer. Journal International Du Cancer. Jan, 2005 | Pubmed ID: 15389514 Embryonic Stem Cells: a Promising Tool for Cell Replacement Therapy Journal of Cellular and Molecular Medicine. Oct-Dec, 2004 | Pubmed ID: 15601575 [Chronic Intermittent Hypoxia Decreases Acute Hypoxic Inhibition of Voltage-gated Potassium Channel in Rat Pulmonary Arterial Smooth Muscle Cells] Sheng Li Xue Bao : [Acta Physiologica Sinica]. Oct, 2004 | Pubmed ID: 15497045 Transcriptional Responses to Epigallocatechin-3 Gallate in HT 29 Colon Carcinoma Spheroids Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Jul, 2004 | Pubmed ID: 15265009 Searching for Reputability: First Randomised Study on Bone-marrow Transplantation in the Heart Lancet. Jul 10-16, 2004 | Pubmed ID: 15246712 Influence of Endostatin on Embryonic Vasculo- and Angiogenesis Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jul, 2004 | Pubmed ID: 15188432 Activity of Complex III of the Mitochondrial Electron Transport Chain is Essential for Early Heart Muscle Cell Differentiation FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2004 | Pubmed ID: 15180963 The Cytosolic II-III Loop of Cav2.3 Provides an Essential Determinant for the Phorbol Ester-mediated Stimulation of E-type Ca2+ Channel Activity The European Journal of Neuroscience. May, 2004 | Pubmed ID: 15147300 Nitric Oxide, a Key Signaling Molecule in the Murine Early Embryonic Heart FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2004 | Pubmed ID: 15132985 Bone Marrow-derived Hematopoietic Cells Generate Cardiomyocytes at a Low Frequency Through Cell Fusion, but Not Transdifferentiation Nature Medicine. May, 2004 | Pubmed ID: 15107841 Regulation of Mitogen-activated Protein Kinase Cascades by Low Density Lipoprotein and Lysophosphatidic Acid Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2004 | Pubmed ID: 15107593 Involvement of Reactive Oxygen Species in Cardiotrophin-1-induced Proliferation of Cardiomyocytes Differentiated from Murine Embryonic Stem Cells Experimental Cell Research. Apr, 2004 | Pubmed ID: 15023522 Arrhythmia in Isolated Prenatal Hearts After Ablation of the Cav2.3 (alpha1E) Subunit of Voltage-gated Ca2+ Channels Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2004 | Pubmed ID: 14976402 Mechanisms of the Inhibitory Effects of Epigallocatechin-3 Gallate on Platelet-derived Growth Factor-BB-induced Cell Signaling and Mitogenesis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2004 | Pubmed ID: 14630705 Effect of Different Vitrification Protocols for Human Ovarian Tissue on Reactive Oxygen Species and Apoptosis Reproduction, Fertility, and Development. 2003 | Pubmed ID: 14975232 [Effect of Linopirdine on Potassium Currents in Isolated Outer Hair Cells and Deiters' Cells of the Cochlea from Guinea Pig] Zhonghua Er Bi Yan Hou Ke Za Zhi. Aug, 2003 | Pubmed ID: 14743634 Identification of Plateled-derived Growth Factor-BB As Cardiogenesis-inducing Factor in Mouse Embryonic Stem Cells Under Serum-free Conditions Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2003 | Pubmed ID: 14631149 Adquisición y análisis de datos en Brainstem Evocada Audiometría de Respuesta en Ratones Andreas Lundt1,2, Julien Soos1, Christina Henseler1, Muhammad Imran Arshaad1, Ralf Müller3, Dan Ehninger4, Jürgen Hescheler5, Agapios Sachinidis5, Karl Broich6, Carola Wormuth1,7, Anna Papazoglou1, Marco Weiergräber1 1Experimental Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices, 2KBRwyle GmbH, 3Cognitive Neurophysiology, Department of Psychiatry and Psychotherapy, Faculty of Medicine, University of Cologne, 4Molecular and Cellular Cognition, German Center for Neurodegenerative Diseases (DZNE), 5Institute of Neurophysiology, Faculty of Medicine, University of Cologne, 6Federal Institute for Drugs and Medical Devices (BfArM), 7Thescon GmbH JoVE 59200 신경과학 Humano madre pluripotentes células Basado Toxicidad para el desarrollo de ensayos de la seguridad química Detección y biología de sistemas de generación de datos Vaibhav Shinde*1, Stefanie Klima*2, Perumal Srinivasan Sureshkumar1, Kesavan Meganathan1, Smita Jagtap1, Eugen Rempel3, Jörg Rahnenführer3, Jan Georg Hengstler4, Tanja Waldmann2, Jürgen Hescheler1, Marcel Leist*2, Agapios Sachinidis*1 1Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne, 2Department of Biology, University of Konstanz, 3Department of Statistics, Technical University of Dortmund, 4Leibniz Research Centre for Working Environment and Human Factors, Technical University of Dortmund JoVE 52333 발생학
Adquisición y análisis de datos en Brainstem Evocada Audiometría de Respuesta en Ratones Andreas Lundt1,2, Julien Soos1, Christina Henseler1, Muhammad Imran Arshaad1, Ralf Müller3, Dan Ehninger4, Jürgen Hescheler5, Agapios Sachinidis5, Karl Broich6, Carola Wormuth1,7, Anna Papazoglou1, Marco Weiergräber1 1Experimental Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices, 2KBRwyle GmbH, 3Cognitive Neurophysiology, Department of Psychiatry and Psychotherapy, Faculty of Medicine, University of Cologne, 4Molecular and Cellular Cognition, German Center for Neurodegenerative Diseases (DZNE), 5Institute of Neurophysiology, Faculty of Medicine, University of Cologne, 6Federal Institute for Drugs and Medical Devices (BfArM), 7Thescon GmbH JoVE 59200 신경과학
Humano madre pluripotentes células Basado Toxicidad para el desarrollo de ensayos de la seguridad química Detección y biología de sistemas de generación de datos Vaibhav Shinde*1, Stefanie Klima*2, Perumal Srinivasan Sureshkumar1, Kesavan Meganathan1, Smita Jagtap1, Eugen Rempel3, Jörg Rahnenführer3, Jan Georg Hengstler4, Tanja Waldmann2, Jürgen Hescheler1, Marcel Leist*2, Agapios Sachinidis*1 1Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne, 2Department of Biology, University of Konstanz, 3Department of Statistics, Technical University of Dortmund, 4Leibniz Research Centre for Working Environment and Human Factors, Technical University of Dortmund JoVE 52333 발생학