Jean-Marc Taymans Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences KU Leuven and Leuven Institute for Neuroscience and Disease (LIND) Biography Publications Institution JoVE Articles Jean-Marc Taymans has not added a biography. If you are Jean-Marc Taymans and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Protein Phosphatase 1 As a Regulator of the LRRK2 Phosphorylation Cycle The Biochemical Journal. Aug, 2013 | Pubmed ID: 23937259 MicroRNA-205 Regulates the Expression of Parkinson's Disease-related Leucine-rich Repeat Kinase 2 Protein Human Molecular Genetics. Feb, 2013 | Pubmed ID: 23125283 Phosphorylation of LRRK2: from Kinase to Substrate Biochemical Society Transactions. Oct, 2012 | Pubmed ID: 22988873 The GTPase Function of LRRK2 Biochemical Society Transactions. Oct, 2012 | Pubmed ID: 22988866 Biochemical Characterization of Highly Purified Leucine-rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers PloS One. 2012 | Pubmed ID: 22952686 Expression, Purification and Preliminary Biochemical and Structural Characterization of the Leucine Rich Repeat Namesake Domain of Leucine Rich Repeat Kinase 2 Biochimica Et Biophysica Acta. Mar, 2012 | Pubmed ID: 22251894 LRRK2 Kinase Activity is Dependent on LRRK2 GTP Binding Capacity but Independent of LRRK2 GTP Binding PloS One. 2011 | Pubmed ID: 21858031 Kinases As Targets for Parkinson's Disease: from Genetics to Therapy CNS & Neurological Disorders Drug Targets. Sep, 2011 | Pubmed ID: 21838679 Insight into the Mode of Action of the LRRK2 Y1699C Pathogenic Mutant Journal of Neurochemistry. Jan, 2011 | Pubmed ID: 21073465 Automated Quantitative Gait Analysis in Animal Models of Movement Disorders BMC Neuroscience. 2010 | Pubmed ID: 20691122 Immunohistochemical Detection of Transgene Expression in the Brain Using Small Epitope Tags BMC Biotechnology. 2010 | Pubmed ID: 20167102 Inhibition of FK506 Binding Proteins Reduces Alpha-synuclein Aggregation and Parkinson's Disease-like Pathology The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2010 | Pubmed ID: 20164329 Mechanisms in Dominant Parkinsonism: The Toxic Triangle of LRRK2, Alpha-synuclein, and Tau BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Mar, 2010 | Pubmed ID: 20127702 The Parkinson's Disease Associated LRRK2 Exhibits Weaker in Vitro Phosphorylation of 4E-BP Compared to Autophosphorylation PloS One. 2010 | Pubmed ID: 20090955 Phosphorylation of Ezrin/radixin/moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2009 | Pubmed ID: 19890007 The Parkinson's Disease Kinase LRRK2 Autophosphorylates Its GTPase Domain at Multiple Sites Biochemical and Biophysical Research Communications. Nov, 2009 | Pubmed ID: 19733152 The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) is a Dimer That Undergoes Intramolecular Autophosphorylation The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18397888 Comparative Analysis of Adeno-associated Viral Vector Serotypes 1, 2, 5, 7, and 8 in Mouse Brain Human Gene Therapy. Mar, 2007 | Pubmed ID: 17343566 Distribution of PINK1 and LRRK2 in Rat and Mouse Brain Journal of Neurochemistry. Aug, 2006 | Pubmed ID: 16771836 Neuroscience Letters. Jan, 2006 | Pubmed ID: 16154268 Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive Phosphate Jean-Marc Taymans1, Fangye Gao1, Veerle Baekelandt1 1Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven and Leuven Institute for Neuroscience and Disease (LIND) JoVE 50523 생물학
Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive Phosphate Jean-Marc Taymans1, Fangye Gao1, Veerle Baekelandt1 1Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven and Leuven Institute for Neuroscience and Disease (LIND) JoVE 50523 생물학