John Koo Psoriasis and Skin Treatment Center Dermatology University of California, San Francisco Biography Publications Institution JoVE Articles John Koo has not added a biography. If you are John Koo and would like to personalize this page please email our Author Liaison for assistance. Publications Delusional Infestations: Clinical Presentation, Diagnosis and Treatment International Journal of Dermatology. Jul, 2013 | Pubmed ID: 23789596 A Randomized Study to Evaluate the Efficacy and Safety of Adding Topical Therapy to Etanercept in Patients with Moderate to Severe Plaque Psoriasis Journal of the American Academy of Dermatology. May, 2013 | Pubmed ID: 23643256 The Impact of Emollients on Phototherapy: a Review Journal of the American Academy of Dermatology. May, 2013 | Pubmed ID: 23399460 Progressive Multifocal Leukoencephalopathy and Reversible Progressive Leukoencephalopathy Syndrome in Dermatologic Therapy Journal of Drugs in Dermatology : JDD. Feb, 2013 | Pubmed ID: 23377400 Delusions of Parasitosis Indian Journal of Dermatology. Jan, 2013 | Pubmed ID: 23372213 Primary Psychiatric Conditions: Dermatitis Artefacta, Trichotillomania and Neurotic Excoriations Indian Journal of Dermatology. Jan, 2013 | Pubmed ID: 23372212 Use of Psychotropic Drugs in Dermatology: Unique Perspectives of a Dermatologist and a Psychiatrist Clinics in Dermatology. Jan-Feb, 2013 | Pubmed ID: 23245980 Update on the Role of Systemic Vitamin D in Atopic Dermatitis Pediatric Dermatology. May-Jun, 2013 | Pubmed ID: 22957498 Goeckerman Therapy: a Very Effective, Yet Often Forgotten Treatment for Severe Generalized Psoriasis The Journal of Dermatological Treatment. Feb, 2013 | Pubmed ID: 22329632 Oral Vitamin D, Still a Viable Treatment Option for Psoriasis The Journal of Dermatological Treatment. Aug, 2013 | Pubmed ID: 22103655 The Role of Tumor Necrosis Factor-alpha and Other Cytokines in Depression: What Dermatologists Should Know The Journal of Dermatological Treatment. Apr, 2013 | Pubmed ID: 21888569 Instant Barrier Repair: A Pilot Study Investigating Occlusion with a New Hydrogel Patch for the Treatment of Atopic Dermatitis The Journal of Dermatological Treatment. Apr, 2013 | Pubmed ID: 21801112 Goeckerman Therapy for the Treatment of Eczema: a Practical Guide and Review of Efficacy The Journal of Dermatological Treatment. Feb, 2013 | Pubmed ID: 21797807 A Prospective, Interventional Assessment of Psoriasis Quality of Life Using a Nonskin-specific Validated Instrument That Allows Comparison with Other Major Medical Conditions Journal of the American Academy of Dermatology. Nov, 2012 | Pubmed ID: 23207011 Treatment of Psoriasis and Long-term Maintenance Using 308 Nm Excimer Laser, Clobetasol Spray, and Calcitriol Ointment: a Case Series Journal of Drugs in Dermatology : JDD. Aug, 2012 | Pubmed ID: 22859247 Trends in Older Adult Psoriasis Outpatient Health Care Practices in the United States Journal of Drugs in Dermatology : JDD. Aug, 2012 | Pubmed ID: 22859241 The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: a Review Dermatology Research and Practice. 2012 | Pubmed ID: 22685455 Excimer Laser Therapy for Hairline Psoriasis: a Useful Addition to the Scalp Psoriasis Treatment Algorithm Skin Therapy Letter. May, 2012 | Pubmed ID: 22622280 Intralesional Injections of Alefacept May Predict Systemic Response to Intramuscular Alefacept: Results from a Pilot Study The Journal of Dermatological Treatment. Jun, 2012 | Pubmed ID: 22506829 Effective Treatment of Etanercept and Phototherapy-resistant Psoriasis Using the Excimer Laser Dermatology Online Journal. Mar, 2012 | Pubmed ID: 22483513 Long-term Etanercept Use for Severe Generalized Psoriasis in an HIV-infected Individual: a Case Study Journal of Drugs in Dermatology : JDD. Mar, 2012 | Pubmed ID: 22395596 Dermatogeriatrics: a Case for Developing a New Dermatology Subspecialty The Journal of Dermatological Treatment. Apr, 2012 | Pubmed ID: 22385040 Quality-of-life Instruments: Evaluation of the Impact of Psoriasis on Patients Dermatologic Clinics. Apr, 2012 | Pubmed ID: 22284142 Long-term Prognosis of Vitiligo Patients on Narrowband UVB Phototherapy Journal of the American Academy of Dermatology. Feb, 2012 | Pubmed ID: 22243727 Open-label, Pilot Study Examining Sequential Therapy with Oral Tacrolimus and Topical Tacrolimus for Severe Atopic Dermatitis Journal of the American Academy of Dermatology. Oct, 2012 | Pubmed ID: 22221776 An Evidence-based Review of Skin Cancer Rates on Biologic Therapies The Journal of Dermatological Treatment. Aug, 2012 | Pubmed ID: 22188512 Psychoneuroimmunology of Psychological Stress and Atopic Dermatitis: Pathophysiologic and Therapeutic Updates Acta Dermato-venereologica. Jan, 2012 | Pubmed ID: 22101513 Cyclosporine and Skin Cancer: an International Dermatologic Perspective over 25 Years of Experience. A Comprehensive Review and Pursuit to Define Safe Use of Cyclosporine in Dermatology The Journal of Dermatological Treatment. Aug, 2012 | Pubmed ID: 21936704 Psoriasis Responds to Intralesional Injections of Alefacept and May Predict Systemic Response to Intramuscular Alefacept: Interim Results of a Single-arm, Open-label Study The Journal of Dermatological Treatment. Apr, 2012 | Pubmed ID: 21254875 Efficacy of Clobetasol Spray: Factors Beyond Patient Compliance The Journal of Dermatological Treatment. Feb, 2012 | Pubmed ID: 21254848 A Review of the Chemopreventative Effects of Oral Retinoids for Internal Neoplasms Journal of Drugs in Dermatology : JDD. Nov, 2011 | Pubmed ID: 22052311 Evaluating the Efficacy and Safety of Calcipotriene/betamethasone Ointment Occluded with a Hydrogel Patch: a 6-week Bilaterally Controlled, Investigator-blinded Trial Cutis; Cutaneous Medicine for the Practitioner. Sep, 2011 | Pubmed ID: 22017069 Practice Gaps. Time and Effort to Establish Therapeutic Rapport with Delusional Patients: Comment on "Delusional Infestation, Including Delusions of Parasitosis" Archives of Dermatology. Sep, 2011 | Pubmed ID: 21931042 Yin-yang Strategy: Proposing a New, Effective, Repeatable, Sequential Therapy for Psoriasis Journal of Drugs in Dermatology : JDD. Aug, 2011 | Pubmed ID: 21818503 Why Are There Significant Differences in Published Narrowband Ultraviolet B Dosimetry Recommendations? The Need for National Standardization of Phototherapy Treatment Journal of the American Academy of Dermatology. Aug, 2011 | Pubmed ID: 21763563 Is Tuberculin Skin Testing Reliable During Anti-tumor Necrosis Factor-alfa Therapy? A Case Report and Review of the Literature Journal of the American Academy of Dermatology. Jul, 2011 | Pubmed ID: 21507516 Introducing the Delayed Retinoid Burn: a Case Report and Discussion of This Potential Risk of Retinoid-phototherapy Combination Management Journal of the American Academy of Dermatology. May, 2011 | Pubmed ID: 21496720 Depression and Acitretin: a True Association or a Class Labeling? Journal of Drugs in Dermatology : JDD. Apr, 2011 | Pubmed ID: 21455552 Guidelines of Care for the Management of Psoriasis and Psoriatic Arthritis: Section 6. Guidelines of Care for the Treatment of Psoriasis and Psoriatic Arthritis: Case-based Presentations and Evidence-based Conclusions Journal of the American Academy of Dermatology. Jul, 2011 | Pubmed ID: 21306785 Paradoxical Worsening of Psoriasis when Switching from Etanercept to Adalimumab: a Case Series The Journal of Dermatological Treatment. Apr, 2011 | Pubmed ID: 20524874 Aripiprazole As a Viable Alternative for Treating Delusions of Parasitosis Journal of Drugs in Dermatology : JDD. Dec, 2010 | Pubmed ID: 21120263 Optimizing Topical Therapies for Treating Psoriasis: a Consensus Conference Cutis; Cutaneous Medicine for the Practitioner. Sep, 2010 | Pubmed ID: 21049712 A Rare Case of Non-Hodgkins B-cell Lymphoma in a Psoriatic Patient: a Case Report and Literature Review Journal of Drugs in Dermatology : JDD. Oct, 2010 | Pubmed ID: 20941955 Phototherapy in Pediatric Patients: Choosing the Appropriate Treatment Option Seminars in Cutaneous Medicine and Surgery. Jun, 2010 | Pubmed ID: 20579600 Psoriasis: Depression, Anxiety, Smoking, and Drinking Habits Dermatologic Therapy. Mar-Apr, 2010 | Pubmed ID: 20415825 Narrowband Ultraviolet B Phototherapy Influences Serum Folate Levels in Patients with Vitiligo Journal of the American Academy of Dermatology. Apr, 2010 | Pubmed ID: 20227588 Broadband UVB Revisited: is the Narrowband UVB Fad Limiting Our Therapeutic Options? The Journal of Dermatological Treatment. Nov, 2010 | Pubmed ID: 19895327 Guidelines of Care for the Management of Psoriasis and Psoriatic Arthritis: Section 5. Guidelines of Care for the Treatment of Psoriasis with Phototherapy and Photochemotherapy Journal of the American Academy of Dermatology. Jan, 2010 | Pubmed ID: 19811850 Pilot Evaluation of Supra-erythemogenic Phototherapy with Excimer Laser in the Treatment of Patients with Moderate to Severe Plaque Psoriasis The Journal of Dermatological Treatment. Jan, 2010 | Pubmed ID: 19711219 Occlusive Therapy in Atopic Dermatitis: Overview The Journal of Dermatological Treatment. Mar, 2010 | Pubmed ID: 19444691 Etanercept in the Treatment of Plaque Psoriasis Clinical, Cosmetic and Investigational Dermatology. 2009 | Pubmed ID: 21436970 Clobetasol Propionate Spray 0.05% Add-on Therapy to a Stable Regimen of Biologic Treatment in Patients with Moderate to Very Severe Plaque Psoriasis Cutis; Cutaneous Medicine for the Practitioner. Oct, 2009 | Pubmed ID: 19916299 Randomized, Double-blind, Placebo-controlled Evaluation of the Efficacy of Oral Psoralen Plus Ultraviolet A for the Treatment of Plaque-type Psoriasis Using the Psoriasis Area Severity Index Score (improvement of 75% or Greater) at 12 Weeks Journal of the American Academy of Dermatology. Nov, 2009 | Pubmed ID: 19766350 Practice of Phototherapy in the Treatment of Moderate-to-severe Psoriasis Current Problems in Dermatology. 2009 | Pubmed ID: 19710550 The Efficacy of Three Class I Topical Synthetic Corticosteroids, Fluocinonide 0.1% Cream, Clobetasol 0.05% Cream and Halobetasol 0.05% Cream: a Scholtz-Dumas Bioassay Comparison Journal of Drugs in Dermatology : JDD. Aug, 2009 | Pubmed ID: 19663113 Guidelines of Care for the Management of Psoriasis and Psoriatic Arthritis: Section 4. Guidelines of Care for the Management and Treatment of Psoriasis with Traditional Systemic Agents Journal of the American Academy of Dermatology. Sep, 2009 | Pubmed ID: 19493586 Efalizumab Discontinuation: a Practical Strategy The Journal of Dermatological Treatment. 2009 | Pubmed ID: 19459081 Guidelines of Care for the Management of Psoriasis and Psoriatic Arthritis. Section 3. Guidelines of Care for the Management and Treatment of Psoriasis with Topical Therapies Journal of the American Academy of Dermatology. Apr, 2009 | Pubmed ID: 19217694 Cooperative Robot Assistant for Retinal Microsurgery Medical Image Computing and Computer-assisted Intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. 2008 | Pubmed ID: 18982647 A Practical Review and Update on the Management of Pruritus Sine Materia Cutis; Cutaneous Medicine for the Practitioner. Sep, 2008 | Pubmed ID: 18856158 Long-term Safety of Mycophenolate Mofetil and Cyclosporine: a Review Journal of Drugs in Dermatology : JDD. Aug, 2008 | Pubmed ID: 18720690 An Updated Review of Acitretin--a Systemic Retinoid for the Treatment of Psoriasis Expert Opinion on Drug Metabolism & Toxicology. Jul, 2008 | Pubmed ID: 18624682 Guidelines of Care for the Management of Psoriasis and Psoriatic Arthritis: Section 2. Psoriatic Arthritis: Overview and Guidelines of Care for Treatment with an Emphasis on the Biologics Journal of the American Academy of Dermatology. May, 2008 | Pubmed ID: 18423261 Guidelines of Care for the Management of Psoriasis and Psoriatic Arthritis: Section 1. Overview of Psoriasis and Guidelines of Care for the Treatment of Psoriasis with Biologics Journal of the American Academy of Dermatology. May, 2008 | Pubmed ID: 18423260 Utilization of Narrow-band Ultraviolet Light B Therapy and Etanercept for the Treatment of Psoriasis (UNITE): Efficacy, Safety, and Patient-reported Outcomes Journal of Drugs in Dermatology : JDD. Mar, 2008 | Pubmed ID: 18380206 Psychopharmacology in Dermatology Dermatologic Therapy. Jan-Feb, 2008 | Pubmed ID: 18318888 The Psychosocial and Occupational Impact of Chronic Skin Disease Dermatologic Therapy. Jan-Feb, 2008 | Pubmed ID: 18318886 Understanding the Psychology of the Cosmetic Patients Dermatologic Therapy. Jan-Feb, 2008 | Pubmed ID: 18318885 Trichotillomania Dermatologic Therapy. Jan-Feb, 2008 | Pubmed ID: 18318881 Morgellons Disease? Dermatologic Therapy. Jan-Feb, 2008 | Pubmed ID: 18318880 Treatment of Psychocutaneous Diseases Dermatologic Therapy. Jan-Feb, 2008 | Pubmed ID: 18318878 Relevance of the COBRA Trial in Current Psoriasis Practice Cutis; Cutaneous Medicine for the Practitioner. Nov, 2007 | Pubmed ID: 18154218 Rebound of Psoriasis After Efalizumab Discontinuation, Despite Being on High-dose Cyclosporine Journal of Drugs in Dermatology : JDD. Sep, 2007 | Pubmed ID: 17941368 Excimer Laser for Psoriasis: a Review of Theories Regarding Enhanced Efficacy over Traditional UVB Phototherapy Journal of Drugs in Dermatology : JDD. Aug, 2007 | Pubmed ID: 17763609 "Unknown Risks" of Non-steroid Topical Medications for Atopic Dermatitis International Journal of Dermatology. Jun, 2007 | Pubmed ID: 17550573 Unraveling the Paradoxes of HIV-associated Psoriasis: a Review of T-cell Subsets and Cytokine Profiles Dermatology Online Journal. 2007 | Pubmed ID: 17498423 An Attempt to Formulate an Evidence-based Strategy in the Management of Moderate-to-severe Psoriasis: a Review of the Efficacy and Safety of Biologics and Prebiologic Options Expert Opinion on Pharmacotherapy. Apr, 2007 | Pubmed ID: 17376017 Using Topical Multimodal Strategies for Patients with Psoriasis Cutis; Cutaneous Medicine for the Practitioner. Jan, 2007 | Pubmed ID: 17367041 Desoximetasone 0.25% and Tacrolimus 0.1% Ointments Versus Tacrolimus Alone in the Treatment of Atopic Dermatitis Cutis; Cutaneous Medicine for the Practitioner. Nov, 2006 | Pubmed ID: 17186796 Predictive Value of Phenotypic Variables for Skin Cancer: Risk Assessment Beyond Skin Typing International Journal of Dermatology. Nov, 2006 | Pubmed ID: 17076706 Morgellons Disease: a Rapport-enhancing Term for Delusions of Parasitosis Journal of the American Academy of Dermatology. Nov, 2006 | Pubmed ID: 17052509 A Randomized, Multicenter Study of Calcipotriene Ointment and Clobetasol Propionate Foam in the Sequential Treatment of Localized Plaque-type Psoriasis: Short- and Long-term Outcomes Journal of the American Academy of Dermatology. Oct, 2006 | Pubmed ID: 17010744 Alefacept in Combination with Ultraviolet B Phototherapy for the Treatment of Chronic Plaque Psoriasis: Results from an Open-label, Multicenter Study Journal of Drugs in Dermatology : JDD. Jul-Aug, 2006 | Pubmed ID: 16865867 Use of Etanercept in Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) Patients International Journal of Dermatology. Jun, 2006 | Pubmed ID: 16796629 The Mechanism of Lithium and Beta-blocking Agents in Inducing and Exacerbating Psoriasis Journal of Drugs in Dermatology : JDD. May, 2006 | Pubmed ID: 16703778 Safety Update on Commonly Used Psychotropic Medications in Dermatology Journal of Drugs in Dermatology : JDD. Feb, 2006 | Pubmed ID: 16485878 Rebound of Psoriasis During Treatment with Efalizumab Journal of Drugs in Dermatology : JDD. Jan, 2006 | Pubmed ID: 16468294 Effect of Ethnicity on the Risk of Developing Nonmelanoma Skin Cancer Following Long-term PUVA Therapy International Journal of Dermatology. Dec, 2005 | Pubmed ID: 16409267 Evidence Based or Theoretical Concern? Pseudotumor Cerebri and Depression As Acitretin Side Effects Journal of Drugs in Dermatology : JDD. Nov-Dec, 2005 | Pubmed ID: 16302554 Psyche, Opioids, and Itch: Therapeutic Consequences Dermatologic Therapy. Jul-Aug, 2005 | Pubmed ID: 16297003 TNF-alpha Inhibitors and Congestive Heart Failure Skinmed. Nov-Dec, 2005 | Pubmed ID: 16276152 Alcohol As a Risk Factor for Plaque-type Psoriasis Cutis; Cutaneous Medicine for the Practitioner. Sep, 2005 | Pubmed ID: 16268261 Psychopharmacologic Therapies in Dermatology: an Update Dermatologic Clinics. Oct, 2005 | Pubmed ID: 16112451 A Review of Acitretin, a Systemic Retinoid for the Treatment of Psoriasis Expert Opinion on Pharmacotherapy. Aug, 2005 | Pubmed ID: 16086658 Tacrolimus Ointment is Safe and Effective in the Treatment of Atopic Dermatitis: Results in 8000 Patients Journal of the American Academy of Dermatology. Aug, 2005 | Pubmed ID: 16021175 A Review of the Chemopreventive and Chemotherapeutic Effects of Topical and Oral Retinoids for Both Cutaneous and Internal Neoplasms Journal of Drugs in Dermatology : JDD. Jul-Aug, 2005 | Pubmed ID: 16004016 Involving the Patient: Impact of Inflammatory Skin Disease and Patient-focused Care Journal of the American Academy of Dermatology. Jul, 2005 | Pubmed ID: 15968267 Decision Points for the Initiation of Systemic Treatment for Psoriasis Journal of the American Academy of Dermatology. Jul, 2005 | Pubmed ID: 15965429 Rosacea, Light, and Phototherapy Journal of Drugs in Dermatology : JDD. May-Jun, 2005 | Pubmed ID: 15898288 Smoking and Psoriasis Skinmed. May-Jun, 2005 | Pubmed ID: 15891254 UVB Phototherapy and Skin Cancer Risk: a Review of the Literature International Journal of Dermatology. May, 2005 | Pubmed ID: 15869531 Update on the Mechanisms and Efficacy of Biological Therapies for Psoriasis Journal of Dermatological Science. May, 2005 | Pubmed ID: 15862940 Review of Cyclosporine Immunosuppressive Safety Data in Dermatology Patients After Two Decades of Use Journal of Drugs in Dermatology : JDD. Mar-Apr, 2005 | Pubmed ID: 15776776 Definitions of Measures of Effect Duration for Psoriasis Treatments Archives of Dermatology. Jan, 2005 | Pubmed ID: 15655149 Pimozide in Dermatologic Practice: a Comprehensive Review American Journal of Clinical Dermatology. 2004 | Pubmed ID: 15554735 Quality-of-life Issues in Psoriasis Dermatologic Clinics. Oct, 2004 | Pubmed ID: 15450335 Narrow-band Ultraviolet B Radiation: a Review of the Current Literature International Journal of Dermatology. Aug, 2004 | Pubmed ID: 15304175 Non-psychotic Uses for Anti-psychotics Journal of Drugs in Dermatology : JDD. Mar-Apr, 2004 | Pubmed ID: 15098971 Psoriasis Journal of the American Academy of Dermatology. Apr, 2004 | Pubmed ID: 15034513 Combination Therapy to Treat Moderate to Severe Psoriasis Journal of the American Academy of Dermatology. Mar, 2004 | Pubmed ID: 14988684 How Do You Foster Medication Adherence for Better Acne Vulgaris Management? Skinmed. Jul-Aug, 2003 | Pubmed ID: 14673276 Psychocutaneous Drug Therapy Seminars in Cutaneous Medicine and Surgery. Sep, 2003 | Pubmed ID: 14649589 The Efficacy of Topical Tazarotene Monotherapy and Combination Therapies in Psoriasis Expert Opinion on Pharmacotherapy. Dec, 2003 | Pubmed ID: 14640932 Validity and Reliability of Patient Reported Outcomes Used in Psoriasis: Results from Two Randomized Clinical Trials Health and Quality of Life Outcomes. 2003 | Pubmed ID: 14613569 Case Studies in Severe Psoriasis: A Clinical Strategy The Journal of Dermatological Treatment. 2003 | Pubmed ID: 14578096 Traditional Chinese Medicine in Dermatology Dermatologic Therapy. 2003 | Pubmed ID: 12919111 Quality of Life Issues in Psoriasis Journal of the American Academy of Dermatology. Aug, 2003 | Pubmed ID: 12894127 Tazarotene Cream in the Treatment of Psoriasis: Two Multicenter, Double-blind, Randomized, Vehicle-controlled Studies of the Safety and Efficacy of Tazarotene Creams 0.05% and 0.1% Applied Once Daily for 12 Weeks Journal of the American Academy of Dermatology. May, 2003 | Pubmed ID: 12734506 Vitamin D and Scalp Psoriasis Cutis; Cutaneous Medicine for the Practitioner. Nov, 2002 | Pubmed ID: 12467336 Psychotropic and Neurotropic Agents in Dermatology: Unapproved Uses, Dosages, or Indications Clinics in Dermatology. Sep-Oct, 2002 | Pubmed ID: 12435529 A Randomized, Double-blind, Placebo-controlled Study of Clobetasol Propionate 0.05% Foam in the Treatment of Nonscalp Psoriasis International Journal of Dermatology. May, 2002 | Pubmed ID: 12100701 Psoriasiform Mycosis Fungoides with Fatal Outcome After Treatment with Cyclosporine Journal of the American Academy of Dermatology. Jul, 2002 | Pubmed ID: 12077599 Combination of Calcipotriene (Dovonex) Ointment and Tazarotene (Tazorac) Gel Versus Clobetasol Ointment in the Treatment of Plaque Psoriasis: a Pilot Study Journal of the American Academy of Dermatology. Jun, 2002 | Pubmed ID: 12063489 Goeckerman方案用于治疗中度至重度牛皮癣 Rishu Gupta1,2, Maya Debbaneh2,3, Daniel Butler2,4, Monica Huynh2,5, Ethan Levin2, Argentina Leon2, John Koo2, Wilson Liao2 1Keck School of Medicine, University of Southern California, 2Psoriasis and Skin Treatment Center Dermatology, University of California, San Francisco, 3University of California Irvine School of Medicine, 4University of Arizona College of Medicine, 5Chicago College of Osteopathic Medicine JoVE 50509 의학
Goeckerman方案用于治疗中度至重度牛皮癣 Rishu Gupta1,2, Maya Debbaneh2,3, Daniel Butler2,4, Monica Huynh2,5, Ethan Levin2, Argentina Leon2, John Koo2, Wilson Liao2 1Keck School of Medicine, University of Southern California, 2Psoriasis and Skin Treatment Center Dermatology, University of California, San Francisco, 3University of California Irvine School of Medicine, 4University of Arizona College of Medicine, 5Chicago College of Osteopathic Medicine JoVE 50509 의학