Joshua Tam Wellman Center for Photomedicine Massachusetts General Hospital Biography Publications Institution JoVE Articles Joshua Tam Joshua Tam is an Instructor in Dermatology at the Wellman Center for Photomedicine, Massachusetts General Hospital. He received his PhD in Biomedical Engineering from the Harvard-MIT division of Health Sciences and Technology, then joined Rox Anderson’s lab at the Wellman Center as a post-doctoral fellow, where he was the lead scientist in developing a new technology to harvest autologous, full-thickness skin in the form of “microcolumns”. These microcolumns can be directly applied into wound beds to accelerate wound healing, similar to conventional autologous minced skin grafts, but with the key advantage that each donor wound is small enough to close spontaneously within days, and without any long-term donor site morbidity or scarring. He was awarded the 2016 Wound Healing Foundation 3M Fellowship for his work. This technology has led to an FDA-cleared device that is now in clinical use. Publications Laser-assisted Delivery of Synergistic Combination Chemotherapy in in Vivo Skin Journal of Controlled Release : Official Journal of the Controlled Release Society. Apr, 2018 | Pubmed ID: 29454062 Reconstitution of Full-thickness Skin by Microcolumn Grafting Journal of Tissue Engineering and Regenerative Medicine. Oct, 2017 | Pubmed ID: 27296503 PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 06, 2016 | Pubmed ID: 26861455 Micro-fractional, Directional Skin Tightening: A Porcine Model Lasers in Surgery and Medicine. Mar, 2016 | Pubmed ID: 26627306 Selective Cryolysis of Sebaceous Glands The Journal of Investigative Dermatology. Sep, 2015 | Pubmed ID: 25860384 Longitudinal, 3D in Vivo Imaging of Sebaceous Glands by Coherent Anti-stokes Raman Scattering Microscopy: Normal Function and Response to Cryotherapy The Journal of Investigative Dermatology. Jan, 2015 | Pubmed ID: 25026458 Chimeric Autologous/allogeneic Constructs for Skin Regeneration Military Medicine. Aug, 2014 | Pubmed ID: 25102552 Pretreatment with Ablative Fractional Laser Changes Kinetics and Biodistribution of Topical 5-aminolevulinic Acid (ALA) and Methyl Aminolevulinate (MAL) Lasers in Surgery and Medicine. Aug, 2014 | Pubmed ID: 24842112 Fractional Skin Harvesting: Autologous Skin Grafting Without Donor-site Morbidity Plastic and Reconstructive Surgery. Global Open. Sep, 2013 | Pubmed ID: 25289241 Paradoxical Effects of PDGF-BB Overexpression in Endothelial Cells on Engineered Blood Vessels in Vivo The American Journal of Pathology. Jul, 2009 | Pubmed ID: 19477947 Blockade of VEGFR2 and Not VEGFR1 Can Limit Diet-induced Fat Tissue Expansion: Role of Local Versus Bone Marrow-derived Endothelial Cells PloS One. Month, 2009 | Pubmed ID: 19333381 Lack of Lymphatic Vessel Phenotype in LYVE-1/CD44 Double Knockout Mice Journal of Cellular Physiology. May, 2009 | Pubmed ID: 19170073 A Mathematical Model of Murine Metabolic Regulation by Leptin: Energy Balance and Defense of a Stable Body Weight Cell Metabolism. Jan, 2009 | Pubmed ID: 19117546 Bone Marrow-derived Mesenchymal Stem Cells Facilitate Engineering of Long-lasting Functional Vasculature Blood. May, 2008 | Pubmed ID: 18256324 Paracrine Regulation of Angiogenesis and Adipocyte Differentiation During in Vivo Adipogenesis Circulation Research. Oct, 2003 | Pubmed ID: 14525808 Apparatus for Harvesting Tissue Microcolumns Joshua Tam1,2, William Farinelli1, Walfre Franco1,2, R. Rox Anderson1,2 1Wellman Center for Photomedicine, Massachusetts General Hospital, 2Department of Dermatology, Harvard Medical School JoVE 58289 생체공학
Apparatus for Harvesting Tissue Microcolumns Joshua Tam1,2, William Farinelli1, Walfre Franco1,2, R. Rox Anderson1,2 1Wellman Center for Photomedicine, Massachusetts General Hospital, 2Department of Dermatology, Harvard Medical School JoVE 58289 생체공학